A common heart failure treatment comes with high risk of stroke—new discovery could make it safer

City of Hope researchers have co-led the first study to demonstrate that characterizing genetic material near chromosomes forecasts how mutated, cancer-causing genes reengineer DNA and alter the tumor microenvironment. The brain cancer research provides foundational knowledge that could one day improve the practice of precision medicine and allow oncologists to deliver more personalized therapies to cancer patients.

Memorial Sloan Kettering Cancer Center researchers have identified a metabolic switch that determines whether intestinal stem cells become absorptive or secretory cells. Manipulating the enzyme OGDH either fuels cell expansion or redirects fate, with potential consequences for colitis recovery and regenerative therapy.

Stroke remains one of the leading causes of death, disability, increased economic burden and decreased quality of life around the world. Current stroke therapies are time-limited and largely focused on restoring blood flow, and there are few which address the secondary wave of inflammation that causes further injury in the hours and days after stroke.

The horrendous images of the Air India plane that crashed yesterday, killing at least 200 of the 242 people who were aboard, are likely to escalate anxiety among many who have an intense fear of flying, say mental health experts.

A new lab-grown material has revealed that some of the effects of aging in the heart may be slowed and even reversed. The discovery could open the door to therapies that rejuvenate the heart by changing its cellular environment, rather than focusing on the heart cells themselves.

The pharmaceutical industry is vital to human health, but it also has a significant environmental impact.

Chemotherapy is a vital treatment for people with all forms of cancer. It's a process that uses drugs designed to kill, damage or slow the spread of cancer cells, preventing them from growing and dividing.

The cerebral cortex, the outermost layer of the brain, is the central driver of various human capabilities, including decision-making, perception, language and memory. Understanding how the morphology (i.e., structure and shape) of people's cerebral cortex is related to their mental health is a long-standing goal for many neuroscientists, as it could help to predict the risk that people will develop specific neuropsychiatric conditions while also contributing to their diagnosis and potentially informing their treatment.

It was 2006 when Dr. Daniel Gibbs first noticed he was losing his sense of smell. But it wasn't what he didn't smell that tipped him off that something might be wrong.

The activity of the human brain is known to be closely connected to other physiological signals, such as heart rate and breathing. A study by researchers at the University of California Los Angeles (UCLA) and other institutes reveals that a global spatiotemporal pattern in the brain (i.e. a pattern in brain activity that repeats itself across the brain and over time) is a central component of these brain-body interactions.

On June 11, 2025, Health Secretary Robert F. Kennedy Jr. announced a slate of eight new members to serve on the Advisory Committee on Immunization Practices, which advises the Centers for Disease Control and Prevention on national vaccine policy.

SGLT2 inhibitors have become a major drug used to treat diabetes, heart failure, and chronic kidney disease. However, there have been questions as to whether it is safe to use these drugs in patients after a recent heart attack due to concerns about harming kidney function in potentially unstable patients.

Vaccinated patients hospitalized with COVID-19 who developed acute kidney injury had better outcomes than unvaccinated patients with the same condition, new research suggests. The study found vaccinated patients were less likely to stay on dialysis after discharge, and more likely to survive, than unvaccinated patients.

A newly published analysis reveals that individuals with severe depression who received electroconvulsive therapy (ECT) were 34% less likely to die by suicide compared to those treated with standard alternatives such as anti-depressant medication.

Children exposed before birth to synthetic compounds called "forever chemicals" had higher blood pressure during their teenage years, according to research published in the Journal of the American Heart Association. The study was also presented at the Society for Epidemiologic Research (SER) Conference in Boston.

Earned sick leave—short-term, paid time off for employees who are sick or injured or must care for sick or injured family members—has been found to reduce the spread of infectious diseases in the workplace and increase employee access to preventive care.

There are more than 100,000 people on organ transplant lists in the U.S., some of whom will wait years to receive one—and some may not survive the wait. Even with a good match, there is a chance that a person's body will reject the organ. To shorten waiting periods and reduce the possibility of rejection, researchers in regenerative medicine are developing methods to use a patient's own cells to fabricate personalized hearts, kidneys, livers, and other organs on demand.

A study conducted at the Botucatu School of Medicine at São Paulo State University (FMB-UNESP) in Brazil has shown that low-dose vitamin D supplementation can increase the effectiveness of chemotherapy treatment in women with breast cancer. The results suggest that the substance could be an alternative to hard-to-access drugs that also aim to increase the response to chemotherapy.