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Bacterial communication delays wound healing by disrupting skin cell repair

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  • 2025-10-15 23:40 event
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Bacterial communication delays wound healing by disrupting skin cell repair
Researchers at University of California San Diego School of Medicine have discovered a previously unrecognized mechanism by which Staphylococcus aureus—one of the most common causes of skin and soft tissue infections worldwide—delays wound healing. The new study reveals that quorum sensing—a process in which bacteria communicate and coordinate behavior with one another—is a key driver of delayed healing in wounds infected by S. aureus. The findings suggest that by using drugs to interfere with quorum sensing, it could be possible to enhance wound healing without relying on antibiotics, reducing the risk of resistance and improving healing outcomes for patients.

31. Immune cell subtype in multiple sclerosis patients may enable targeted treatment

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Multiple sclerosis, which affects around one in 500 people in Switzerland, is an autoimmune disease in which immune cells attack the central nervous system, causing irreversible damage. Current treatments involve blocking the immune system to prevent it from attacking the body. Although effective, these drugs can trigger potentially serious infections.

32. Locally transmitted malaria made US return in 2023

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After a 20-year absence, there were 10 cases of locally transmitted malaria in the United States in 2023, according to a study published online Oct. 6 in JAMA Network Open.

33. Study of 267,000 kids reveals the hidden burden of multiple developmental conditions

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Our new study highlights a crucial, but often hidden, aspect of child health—the mental health impact of living with two or more neurodevelopmental conditions.

34. Food processing level outweighs plant-based label for heart health benefits, study finds

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Previous studies have reported that a high consumption of ultra-processed foods is associated with an increased risk of developing cardiovascular diseases, while other studies have shown that a diet including a large proportion of plant-based products—when nutritionally balanced—may reduce the risk of developing these diseases.

35. Bioadhesive sponge inspired by mussels and extracellular matrix offers new way to stop internal bleeding

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Uncontrolled bleeding during surgery remains one of the deadliest medical emergencies. Injuries to internal organs such as the liver or spleen are especially dangerous because bleeding is difficult to control and often life-threatening.

36. Too much, too little sleep tied to overactive bladder risk

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The risk for overactive bladder (OAB) is associated with both short and long sleep duration, according to a study published online Sept. 17 in Frontiers in Medicine.

37. Vascular mechanism may explain persistence of COVID-19 symptoms and their greater impact, especially in women

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A research team led by IGTP, in collaboration with IR Sant Pau and ISGlobal, identifies a protein as a central element in long COVID and highlights differences according to sex and hormonal status.

38. Touching your face may reveal hidden stress

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Spontaneous facial self-touching may be an evolutionary, self-soothing behavior that helps regulate stress, according to researchers from the University of Houston and Virginia Tech.

39. FDA clears new blood test to help rule out Alzheimer's disease

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The U.S. Food and Drug Administration (FDA) has cleared another blood test that could help doctors identify whether a patient's memory problems are likely caused by Alzheimer's disease.

40. Bacterial communication delays wound healing by disrupting skin cell repair

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Researchers at University of California San Diego School of Medicine have discovered a previously unrecognized mechanism by which Staphylococcus aureus—one of the most common causes of skin and soft tissue infections worldwide—delays wound healing. The new study reveals that quorum sensing—a process in which bacteria communicate and coordinate behavior with one another—is a key driver of delayed healing in wounds infected by S. aureus. The findings suggest that by using drugs to interfere with quorum sensing, it could be possible to enhance wound healing without relying on antibiotics, reducing the risk of resistance and improving healing outcomes for patients.

41. California to require food allergen labels on menus by 2026

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Starting in 2026, restaurant chains in California will be required to list major food allergens on their menus in a first-of-its-kind law.

42. Arthritis pain rising: How state policies matter

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New research from The University of Texas at Arlington shows that differences in state welfare policies are linked to rising arthritis-related joint pain across much of the U.S.

43. Yes, ADHD diagnoses are rising, but that doesn't mean it's overdiagnosed

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Many news outlets have reported an increase—or surge—in attention-deficit/hyperactivity disorder, or ADHD, diagnoses in both children and adults. At the same time, health care providers, teachers and school systems have reported an uptick in requests for ADHD assessments.

44. How wildfires and other climate disasters put health systems under extreme pressure

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Wildfires are no longer rare disasters in Canada. They are now an annual reality, and 2025 has already been one of the worst on record, with 3,582 fires burning 6.2 million hectares as of July 30—quadruple the 10-year average.

45. Conversion of IgG antibodies to IgM broadens antibacterial activity

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Researchers at UMC Utrecht have discovered that converting monoclonal antibodies from the IgG to the IgM isotype can significantly broaden their ability to recognize and bind multiple human-relevant bacterial pathogens. The study is published in Cell Reports Medicine.

46. Focused sound energy holds promise for treating cancer, Alzheimer's and other diseases

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Sound waves at frequencies above the threshold for human hearing are routinely used in medical care. Also known as ultrasound, these sound waves can help clinicians diagnose and monitor disease, and can also provide first glimpses of your newest family members.

47. Absence of key protein scrambles sperm DNA, revealing potential cause of male infertility

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Researchers from the Universitat Autònoma de Barcelona (UAB) have published an analysis that reveals new functions of the RAD21L protein—a germline-specific cohesin—crucial for male fertility. The study, carried out in mice and in collaboration with the Spanish National Research Council (CSIC), the University of Salamanca, and the National Center for Genomic Analysis (CNAG) of Barcelona, is published in the journal Science Advances.

48. Researchers show benefit of ultra-deep RNA sequencing in Mendelian disorder diagnostics

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RNA sequencing (RNA-seq) is a powerful tool in diagnosing Mendelian disorders, but the optimized sequencing depth for this technology has not yet been determined. In a new study published in the American Journal of Human Genetics, researchers at Baylor College of Medicine's Medical Genetics Multiomics Laboratory (MGML) show the utility and benefit of ultra-deep RNA sequencing in clinical diagnostics.

49. Eye-tracking offers measure of change in pre-clinical Alzheimer's disease

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The effectiveness of eye-tracking technology in identifying people who have a genetic tendency to Alzheimer's disease, years before their symptoms show, has been highlighted in new research.

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