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Breathlessness increases long-term mortality risk, finds a study in Malawi

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  • 2025-09-11 06:00 event
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Breathlessness increases long-term mortality risk, finds a study in Malawi
Research led by Liverpool School of Tropical Medicine and the Malawi-Liverpool-Wellcome Program shows that over half of hospital patients with breathlessness had died within a year of admission (51%), as opposed to just 26% of those without the symptom.

540. FDA releases guidance to promote nonopioid alternatives for chronic pain

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The U.S. Food and Drug Administration released draft guidance to advance safe and effective nonopioid treatment options and reduce risks tied to prescription opioid misuse.

541. Bushfire smoke and COVID-19: Study reveals lessons from Canadian wildfires

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Australian public health authorities have been urged to prepare for a possible increase in severe COVID-19 cases during the local bushfire season, following a QUT-led study that suggests there was a strong link between wildfire smoke exposure and increased COVID-19 hospitalizations in New York State after the 2023 Quebec wildfires.

542. Distinct psilocybin-induced oscillations observed in rat medial prefrontal cortex, with effects lasting days

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Psychedelics, a class of psychoactive drugs that typically induce peculiar mental states and hallucinations, are still prohibited for recreational use in most countries worldwide. In recent years, some neuroscientists and medical researchers have been exploring the potential therapeutic effects of these drugs, focusing on the treatment of depression, anxiety and various substance use disorders.

543. Experts shape global roadmap to reduce anemia

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Duke-NUS Medical School, working with an international team of experts, has contributed to a new evidence-based plan to tackle anemia—a condition affecting nearly two billion people worldwide and a persistent obstacle to achieving global health goals.

544. Customized gene-editing technology shows potential to treat lethal pediatric disease

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Multisystemic smooth muscle dysfunction syndrome (MSMDS) is a rare condition associated with stroke, aortic dissection (tearing) and death in childhood. Currently, there is no effective treatment or cure for MSMDS.

545. Alzheimer's disease digital resources lacking for Latinos, Hispanics in Los Angeles years after COVID-19, study finds

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Although Latinos and Hispanics are at elevated risk for Alzheimer's disease and account for almost half of Los Angeles County's population, a recent UCLA Health study finds that accessible digital resources for these communities remain in short supply since the COVID-19 pandemic.

546. West Nile virus cases running higher than normal, prompting health warnings

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West Nile virus infections are intense so far this year, with case counts running 40% higher than normal, health officials say.

547. Drug-resistant fungus C. auris confirmed to be spreading rapidly in European hospitals

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The latest survey from the European Center for Disease Prevention and Control (ECDC), the fourth of its kind, confirms that Candidozyma auris (formerly Candida auris) continues to spread quickly across European hospitals, posing a serious threat to patients and health care systems.

548. Study sheds light on hurdles faced in transforming NHS health care with AI

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Implementing artificial intelligence (AI) into NHS hospitals is far harder than initially anticipated, with complications around governance, contracts, data collection, harmonization with old IT systems, finding the right AI tools and staff training, finds a major new UK study led by UCL researchers.

549. Breathlessness increases long-term mortality risk, finds a study in Malawi

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Research led by Liverpool School of Tropical Medicine and the Malawi-Liverpool-Wellcome Program shows that over half of hospital patients with breathlessness had died within a year of admission (51%), as opposed to just 26% of those without the symptom.

550. Inhibiting an astrocytic 'brake' that blocks spinal cord repair could pave path to neuronal regeneration

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Spinal cord injuries caused by external trauma, such as traffic accidents or falls, often lead to the permanent loss of motor and sensory functions. This is because the spinal cord—the central pathway connecting the brain and the rest of the body—harbors a "brake" mechanism that halts repair. For the first time, the molecular mechanism behind this braking system has been revealed.

551. Analysis suggests chronic disease deaths are declining globally, but progress is slowing

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Death rates from chronic diseases have fallen in four out of five countries around the world in the last decade—but progress has slowed, suggests an analysis led by researchers at Imperial College London and published in The Lancet.

552. Parent-focused programs fail to prevent obesity in toddlers, analysis finds

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Existing approaches to behavioral programs targeted at parents with children up to age 12 months and that aim to combat childhood obesity are insufficient to improve body mass index (BMI) at approximately two years of age, according to the largest study to date on the topic, published in The Lancet.

553. AI detects subtle movement changes in finger-tapping videos, revealing hidden Parkinson's signs

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Early detection of even the slightest motor function changes can be critical to slowing the progression of Parkinson's disease. Yet these subtle signs often go unnoticed. Now, UF researcher Diego L. Guarín, Ph.D., is harnessing AI to spot these subtle changes from video recordings before clinical symptoms become evident to the clinician's eyes.

554. Study finds decline in long-term benzodiazepine use among older adults, but risks remain

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Older adults are increasingly discontinuing benzodiazepines soon after hospital discharge, but a significant number continue use for months, putting them at risk for serious health problems, according to new research published in the Journal of the American Geriatrics Society.

555. AI model helps identify therapeutic antibodies to boost pandemic preparedness

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Scientists at Scripps Research have developed a novel method that uses artificial intelligence (AI) and advanced imaging techniques to more accurately and efficiently identify therapeutic antibodies to treat infectious diseases.

556. Antioxidant shield for T cell telomeres shows promise against tumor-induced exhaustion

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Tumors are stressful places for cancer-fighting immune cells. Low oxygen, high acid levels, and other stressors put strain on mitochondria, the cell's energy factories, leading to T cell exhaustion and poor cancer outcomes.

557. Green tea improves insulin sensitivity and glucose tolerance in obese mice

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Green tea is an ancient beverage recognized for its medicinal and antioxidant properties. It has been widely studied for its beneficial effects on metabolic diseases, such as obesity and type 2 diabetes. Recent studies have deepened our understanding of the mechanisms of action of this infusion and revealed that green tea treatment reduced weight and significantly improved glucose sensitivity and insulin resistance in obese mice. These results reinforce the potential relevance of the beverage as an adjunct in the treatment of obesity in humans.

558. Media visibility and costs of new medicines under examination—what does the media highlight?

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A study conducted by the University of Eastern Finland and Fimea found that the Finnish news media has given GLP-1 agonists used to treat obesity, such as semaglutide, a great deal of attention while many other new medicines have been ignored. Based on preliminary results, media visibility is not evenly divided between medicines intended for different indications, and the amount of visibility does not always correspond to such things as the user-specific costs of medicines or the prevalence of indications.

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