Caffeine may undermine blood transfusion effectiveness

Today, when an aging parent, relative, or friend starts to forget things, a firm diagnosis can be surprisingly elusive.

Input and expertise from radiologists can help develop better and more trustworthy artificial intelligence (AI) tools, new research shows. The study used radiologists' eye movements to help guide AI systems to focus on the most clinically relevant areas of medical images.

Intense light therapy after surgery can increase a critical protein that protects heart tissue while lowering levels of troponin, a protein indicating heart damage that's linked to higher mortality in patients undergoing non-cardiac surgery, according to a study by researchers at CU Anschutz.

As the effectiveness of antibiotics meant to fight the deadly superbug Clostridioides difficile, or C. diff, wanes, a research team at the University of Houston is seeing positive results of a new antibiotic on the scene—ibezapolstat—which is proving successful in fighting these infectious bacteria in clinical trials.

Mavacamten treatment at 48 weeks was not associated with significant improvements in patient-reported health status or peak oxygen consumption compared with placebo in patients with symptomatic nonobstructive hypertrophic cardiomyopathy, according to late-breaking research presented in a Hot Line session today at ESC Congress 2025 and simultaneously published in New England Journal of Medicine.

A team of researchers at Johns Hopkins Medicine say they have revealed a possible molecular connection between air pollution and an increased risk of developing Lewy body dementia.

Cells on the inner surface of the intestine are replaced every few days. But, how does this work? It was always assumed that cells leave the intestinal surface because excess cells are pushed out.

An increasing number of young Australians are autistic. About 4.4% of children aged to 10 to 14 years and 3.4% of older teens have an autism diagnosis.

Health authorities in the Democratic Republic of Congo have declared a new outbreak of the Ebola virus, which has killed 15 people since the end of August, the health minister said Thursday.

Vladimir Putin and Xi Jinping have been recorded on a hot mic discussing how organ transplants and other medical advances could let humans live past 150 years—or even become immortal.

A toxic protein forms dynamic pores in the membranes of brain cells—and that may be the key to understanding how Parkinson's disease develops. This is the conclusion of a new study from Aarhus University, where researchers have developed an advanced method to track molecular attacks in real time.

Playwright William Congreve wrote in the Restoration period that music "hath charms to soothe a savage breast." And, as it turns out, back pain in 21st-century patients as well.

Pain and sleep disturbances often go hand in hand—more than 30% of the U.S. population lives with pain, and a majority of those with pain also report sleep disorders—but the relationship between the two has remained largely unexplored.

Researchers from the University of Hong Kong have discovered that the Epstein-Barr virus (EBV), a common human virus closely linked to nasopharyngeal carcinoma (NPC), can change the 3D structure of the human genome inside cancer cells, much like assembling building blocks.

Neuroinflammation, a prolonged activation of the brain's immune system prompted by infections or other factors, has been linked to the disruption of normal mental functions. Past studies, for instance, have found that neuroinflammation plays a central role in neurodegenerative diseases, medical conditions characterized by the progressive degradation of cells in the spinal cord and brain.

A specific bacterial infection during pregnancy that can cause severe harm to the unborn brain has been identified for the first time, in a finding that could have huge implications for prenatal health.

A research group has revealed that transcription factors RUNX2 and BHLHE40 play crucial roles in inducing T cells involved in Crohn's disease. Crohn's disease is an intractable disorder characterized by chronic inflammation in the digestive tract. Tissue-resident memory T cells (TRM), which persist long-term in the intestinal mucosa, have been implicated in disease pathogenesis, but it has not been clear how these cells are induced.

Cancer cells have one relentless goal: to grow and divide. While most stick together within the original tumor, some rogue cells break away to traverse to distant organs. There, they can lie dormant—undetectable and not dividing—for years, like landmines waiting to go off.