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Changes in biology of internal fat may be the leading cause of heart failure

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  • 2025-08-31 14:00 event
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Changes in biology of internal fat may be the leading cause of heart failure
Heart failure with preserved ejection fraction (HFpEF) appears to develop as a result of changes in the biology of a person's internal fat tissue, according to the Adipokine Hypothesis, a new way of understanding how fat may impact the heart.

1.287. Childhood Cancer Awareness Month 2025

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Distribution of gifts to cancer patients on International Childhood Cancer Day 2025. Photo: WHO 1 September 2025 – Globally, 400 000 children are diagnosed with cancer annually, which means 3 children are diagnosed with cancer every 4 minutes. Of these cases, 90% occur in low- and middle-income countries, where only a fifth of diagnosed children survive. In contrast, children born in high-income countries have a more than 80% chance of surviving childhood cancer. The difference in survival rates is one of the most significant inequalities across cancer types. Behind each statistic is a child’s story. To ensure these stories shape policies and inspire change, the voices of survivors must be heard. During the recent national childhood cancer stakeholder workshop held in Egypt, 4 cancer survivors explained how their journeys shaped their perceptions of the gift of life and spoke about the tremendous efforts by health care providers and their families to relieve their pain and uncertainty. They said the peer support they received and the social bonds they developed with other childhood cancer survivors brightened the most difficult days. The workshop was inaugurated by H.E. the Minister of Health and Population Dr Khaled Abdel-Ghaffar who listened attentively to the speakers. In 2018, Read more...

1.288. Metformin changes blood metal levels in humans, offering further insight into its mechanism of action

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The widely used diabetes drug metformin changes blood metal levels in humans. The Kobe University study is an important step in understanding the drug's many actions and designing better ones in the future.

1.289. Fall allergy symptoms are similar to spring and summer—and can hit as hard

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If you're wondering why your spring allergy symptoms never went away, it's possible you are suffering from spring… into summer… into fall allergies.

1.290. Can kids overdose on melatonin gummies? Yes, and an online store has suspended sales

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US-based online store iHerb has suspended sales of melatonin gummies to Australia. This comes after a rise in reports of non-fatal overdoses in Western Australia in children who took these popular supplements.

1.291. Tracking the UV? Ditching the SPF? Here's what a dermatologist says

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This summer, TikTok and Instagram feeds have been full of a new ritual: "checking the UV." Gen Z content creators are tracking the daily UV index—not to avoid the sun, but to head outside when it's strongest for what they see as the "optimal" tan. At the same time, some social media influencers are spreading claims that sunscreen is harmful or unnecessary, a trend that has dermatologists increasingly concerned.

1.292. Researchers train AI to diagnose heart failure in rural patients using low-tech electrocardiograms

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Concerned about the ability of artificial intelligence models trained on data from urban demographics to make the right medical diagnoses for rural populations, West Virginia University computer scientists have developed several AI models that can identify signs of heart failure in patients from Appalachia.

1.293. Gender-affirming surgeries may be added to Medicare—but the evidence is still being reviewed

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For the first time in Australia, an independent committee is considering whether Medicare should fund gender-affirming surgery for trans adults (those aged 18 and over).

1.294. People's brain structure linked to their genetic risk of major depression, stud finds

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Depression is among the most widespread psychiatric disorders, experienced by an estimated 3.8% of the global population. It is characterized by persistent low mood and a loss of interest in most activities, as well as possible disruptions in eating and sleeping habits.

1.295. People's brain structure linked to their genetic risk of major depression, study finds

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Depression is among the most widespread psychiatric disorders, experienced by an estimated 3.8% of the global population. It is characterized by persistent low mood and a loss of interest in most activities, as well as possible disruptions in eating and sleeping habits.

1.296. Changes in biology of internal fat may be the leading cause of heart failure

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Heart failure with preserved ejection fraction (HFpEF) appears to develop as a result of changes in the biology of a person's internal fat tissue, according to the Adipokine Hypothesis, a new way of understanding how fat may impact the heart.

1.297. Why endurance events like marathons should have weight divisions for heavier runners

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In sports such as wrestling, boxing, rowing, weight lifting and the martial arts, athletes are grouped by weight to make things fairer.

1.298. Labor Day mission: Build social ties through live events

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If your social life has been lived out in Zoom calls since the height of the pandemic, Labor Day weekend is prime time for a reboot.

1.299. FDA now providing daily updates on adverse events

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The U.S. Food and Drug Administration is now providing real-time, daily publication updates on adverse event data from its reporting system.

1.300. Childhood trauma linked to mental health problems and chronic pain in later life

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New research from the University of Aberdeen challenges the current view that trauma in childhood increases the risk of all health conditions. The study found instead that some conditions are more affected than others and women are more affected than men.

1.301. 'We need to look after our grand-friends': How childcare in aged care can help young and old

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An experimental aged-care model in South Australia, where purpose-built independent retirement living apartments are co-located with an early learning center, is seeking to foster connections between residents and children.

1.302. Can vitamin D supplements really slow aging, as a recent study suggests?

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Vitamin D supplements could help protect the caps on our chromosomes that slow aging, sparking hopes the sunshine vitamin might keep us healthier for longer, a recent study suggests.

1.303. One shot of RSV vaccine found effective against hospitalization in older adults for two seasons

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One shot of an RSV vaccine protects adults aged 60 or older from RSV-associated hospitalization and critical illness during two consecutive RSV seasons, according to a study published in JAMA by the IVY Network research group.

1.304. Beta blockers may offer no benefit for heart attack patients, and women can have worse outcomes

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Beta blockers—drugs commonly prescribed for a range of cardiac conditions, including heart attacks—provide no clinical benefit for patients who have had an uncomplicated myocardial infarction with preserved heart function. Beta blockers have been the standard treatment for these patients for 40 years.

1.305. Stubborn high blood pressure drops with an experimental drug that targets hormone imbalance

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A new treatment has been shown to significantly lower blood pressure in people whose levels stay dangerously high, despite taking several existing medicines, according to the results of a Phase III clinical trial led by a UCL Professor.

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