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Cholesterol buildup in liver fat droplets directly drives fibrosis in metabolic disease, study finds

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  • 2025-07-30 20:47 event
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Cholesterol buildup in liver fat droplets directly drives fibrosis in metabolic disease, study finds
Cholesterol plays a vital role in the body, providing structural support to cells and serving as a building block for hormone synthesis. However, when cholesterol accumulates or is improperly distributed, it can contribute to the development and progression of disease.

977. How the brain shapes what we feel in real time: A new mechanism for modulating sensory signals

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The cerebral cortex processes sensory information via a complex network of neural connections. How are these signals modulated to refine perception? A team from the University of Geneva (UNIGE) has identified a mechanism by which certain thalamic projections target neurons and modify their excitability.

978. Research reveals alarming decline in youth mental health in England

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A major new report, "Understanding drivers of recent trends in young people's mental health," reveals that worsening mental health among 14–24-year-olds in England is real, widespread, and driven by identifiable social and economic factors. The study, commissioned by the Youth Futures Foundation, is the first of its kind to explore the underlying reasons behind this troubling trend at the population level.

979. Early challenges to the immune system disrupt oral health

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Modupe O. Coker from the School of Dental Medicine and a collaborative team of researchers identified changes over time in the oral microbiome of children living with HIV, offering insights into how early immune challenges shape not only oral health but also systemic health.

980. 'Fairy rings' in yards signal presence of harmful white mushrooms

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Circles of white mushrooms, or "fairy rings," may add a whimsical touch to summer lawns. But beware—they're probably poisonous.

981. The US is not ready for its aging population—research explains why

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America is aging, and it's not ready, according to new research.

982. Smart wound monitor poised to improve chronic infection care

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Researchers from RMIT University have developed a wearable wound monitoring device with integrated sensors that could reduce infection risks by minimizing the need for frequent physical contact. Their study, "Multiplexed cutaneous wound monitor for point-of-care applications," was published in Advanced NanoBiomed Research.

983. How do our genes influence our sense of smell? Study finds sex-specific effects

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How we smell is not just a matter of taste—it's also influenced by our genes. An international team of researchers led by scientists from Leipzig University has conducted the largest genetic study to date on the human sense of smell. Researchers at the Institute for Medical Informatics, Statistics and Epidemiology (IMISE) identified seven new genetic regions associated with our ability to perceive odors.

984. Study finds no increased cardiovascular risk from cannabis in older heart patients

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A new study brings reassuring news for older adults using cannabis: smoking or consuming cannabis does not appear to raise the risk of heart attacks, strokes or cardiovascular death—at least among older veterans with pre-existing heart disease.

985. Study finds genetics and personality traits shape early teen drinking risk

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The risk for teenage alcohol use is shaped by more than just peer pressure or curiosity, according to a Rutgers-led study.

986. Cholesterol buildup in liver fat droplets directly drives fibrosis in metabolic disease, study finds

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Cholesterol plays a vital role in the body, providing structural support to cells and serving as a building block for hormone synthesis. However, when cholesterol accumulates or is improperly distributed, it can contribute to the development and progression of disease.

987. Many UK obstetricians and gynecologists suffer from burnout, survey suggests

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A national survey of obstetricians and gynecologists has revealed high levels of burnout in the sector since the COVID-19 pandemic.

988. Why some strep infections turn deadly: A genetic clue

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A group of researchers led by the University of Osaka have identified a novel genetic mutation in Streptococcus pyogenes, a common bacterium which causes strep throat, significantly associated with severe invasive infections.

989. Global experts want management of multiple sclerosis in older people overhauled

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Global experts, including several from Monash University, have developed guidelines to better manage multiple sclerosis (MS) in people over 50.

990. Study identifies new target for obesity-related breast cancer

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University of Kentucky Markey Cancer Center researchers have identified a protein that could be a promising treatment target for obesity-related breast cancer.

991. Young men with passive approach to news tend to believe medical misinformation

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True or false?

992. Treating hypertension with single pill combinations saves lives and money

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A new Australian study published in the latest issue of the Journal of Hypertension shows that treating hypertension with single pills combining two or more medications provides effective control and also delivers substantial cost savings to both consumers and payers, when compared with equivalent doses in multiple pills.

993. Wearable device uses ambient light for 24-hour health monitoring

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Miniaturization and weight reduction of medical wearable devices for continuous health monitoring such as heart rate, blood oxygen saturation, and sweat component analysis remain major challenges. In particular, optical sensors consume a significant amount of power for LED operation and wireless transmission, requiring heavy and bulky batteries.

994. How the common fungus Candida albicans colonizes the gut

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About 80% of people have the fungus Candida albicans in their gut. Although most of the time it persists unnoticed for years, causing no health problems, C. albicans can turn into a dangerous microbe that causes serious diseases in many organs, including the urinary tract, lungs and brain. Understanding how this fungus colonizes the gut is key to preventing it from becoming harmful.

995. A single artificially sweetened soft drink daily may increase diabetes risk by more than a third

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An Australian study has found that drinking just one can of artificially-sweetened soft drink a day may increase the risk of developing type 2 diabetes by 38%.

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