Click chemistry PET imaging tracks antisense drug distribution in the brain

Any high school reunion is a sharp reminder that some people age more gracefully than others. Some enter their older years still physically spry and mentally sharp. Others start feeling frail or forgetful much earlier in life than expected.

Epilepsy is among the most common neurological conditions, marked by unpredictable seizures, accidents and injuries, reduced quality of life, stigma and—in the worst case—premature death.

There is new evidence suggesting therapy may lead to higher recovery rates than medication in people over 60 who experience anxiety disorders, says Associate Professor Carly Johnco.

While glucose, or sugar, is a well-known fuel for the brain, Weill Cornell Medicine researchers have demonstrated that electrical activity in synapses—the junctions between neurons where communication occurs—can lead to the use of lipid or fat droplets as an energy source.

A new study by researchers at University College Cork (UCC), Ireland, found that 60% of pregnant women had suboptimal iodine status, highlighting a need for increased nutritional awareness to support maternal and child health.

Traditional histopathology, crucial for disease diagnosis, relies on chemically staining tissue samples to highlight cellular structures for microscopic examination by pathologists. This labor-intensive "histochemical staining" process is time-consuming, costly, requires chemical reagents, and is destructive to the tissue.

A new study has identified early-pregnancy gut microbiota signatures associated with the development of gestational diabetes mellitus, a metabolic disorder that carries substantial risks to both maternal and fetal health.

Experts have warned against simply throwing money and new equipment at disadvantaged communities to tackle the problem of inequitable health care.

Left main coronary artery (LMCA) disease can lead to what's known as a "widowmaker" heart attack, so-called because of the low odds of survival. But this can be avoided if someone is given a stent to open up the narrowed LMCA, or heart bypass surgery.

More than 14 million of the world's most vulnerable people, a third of them small children, could die by 2030 because of the Trump administration's dismantling of US foreign aid, research projected on Tuesday.

The U.S. Food and Drug Administration has approved GSK's autoinjector of Benlysta (belimumab) for subcutaneous injection in patients ≥5 years of age with active lupus nephritis who are receiving standard therapy.

Cookouts on the Fourth of July aren't just a tradition—they're expected as part of a day of outdoor games, fireworks and fun.

Research led by the Department of General and Visceral Surgery, Faculty of Medicine, University of Freiburg, Germany has found that bile acid diversion in Roux-en-Y gastric bypass (RYGB) reduces colorectal tumor growth and metastasis independent of weight loss, potentially reshaping future cancer treatment approaches.

New research has uncovered an imbalanced sex ratio at birth among Australia's migrant populations, with some migrant mothers seeming to prefer boys to girls.

Suriname has become the first Amazonian country to eliminate malaria after 70 years of fighting the mosquito-borne disease, the World Health Organization (WHO) announced Monday.

For the first time, scientists have systematically studied the genetic effects of chemotherapy on healthy tissues.

A new study challenges the belief in a universal "pet effect" on human well-being. Using data collected during COVID-19 lockdowns, researchers found no significant change in respondents' well-being when they acquired or lost a pet in their household.

A UCSF analysis has found that the newer generation of much more effective diabetes medications are reaching only a fraction of the patients who are recommended to take them based on new guidelines.