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Colonoscopy screening at age 45 yields neoplasia rates close to older adults: Study supports guideline change

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  • 2025-06-05 20:40 event
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Colonoscopy screening at age 45 yields neoplasia rates close to older adults: Study supports guideline change
Researchers from Kaiser Permanente Northern California reveal that adults aged 45 to 49 undergoing their first screening colonoscopy have neoplasia detection rates similar to those aged 50 to 54, supporting recent guideline changes to begin colorectal cancer screening earlier.

2.503. Increasing numbers of US adults don't know they have diabetes, high blood pressure or high cholesterol

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In a new report published in JAMA Cardiology, health policy experts at the Richard A. and Susan F. Smith Center for Outcomes Research at Beth Israel Deaconess Medical Center (BIDMC) have shown that many US adults are unaware they have high blood pressure, diabetes and high cholesterol—three major risk factors for cardiovascular disease and death.

2.504. Q&A: Worried about getting a CT scan? Here's what to ask your doctor

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Medical imaging scans that create detailed images of the body's internal structures are widely used in medicine. Doctors need them to detect and manage certain types of cancer, assess the extent of traumatic injuries, and diagnose and treat many other medical conditions.

2.505. Biking in an MRI machine could help physicians to check your heart health

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A quarter of deaths in the UK are caused by heart disease, the equivalent of one person every three seconds. Improving diagnostics will allow for earlier diagnosis and better health outcomes.

2.506. Obesity can raise colorectal cancer risk by 30–50%, study finds

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Colorectal cancer (CRC) remains one of the leading causes of cancer-related deaths worldwide. While genetics and age are well-known risk factors, growing evidence highlights a significant connection between obesity and colorectal cancer. Understanding this link is crucial in shaping effective prevention and early detection strategies.

2.507. Metabolic markers found in obese adolescents guide vascular aging intervention

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A new study provides a comprehensive overview of the current state of metabolomics research in arterial stiffness on a less explored aspect: early vascular aging, particularly in adolescents. The study offers hope for innovative approaches to vascular health.

2.508. Adopting a healthy diet may have cardiometabolic benefits regardless of weight loss

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Nearly one-third of people who adopted and adhered to a healthy diet did not lose any weight, but still reaped many health benefits, according to a new study led by researchers at Harvard T.H. Chan School of Public Health and Ben Gurion University, Israel.

2.509. New approach reverses opioid overdoses more safely, rat study shows

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Opioid overdoses are a major public health issue in the U.S., killing tens of thousands of people every year. The medicine naloxone, which is available as an over-the-counter nasal spray or given by injection, has saved countless lives by rapidly reversing opioid overdoses. But in blocking opioid receptors in the brain, naloxone causes severe withdrawal symptoms, including pain, vomiting and agitation.

2.510. Cancer diagnosis on your laptop? New artificial intelligence model makes it possible

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Imagine diagnosing cancer not with a supercomputer but on an ordinary laptop instead. Sounds like science fiction? Thanks to a revolutionary artificial intelligence (AI) model developed by Professor Kenji Suzuki and his research team from Institute of Science Tokyo (Science Tokyo), this far-fetched scenario is now a reality.

2.511. Organoids containing blood vessels have been grown, holding promise for research and treatment

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For over a decade, scientists have been growing organoids—small clusters of cells that mimic a particular organ—to serve as miniature biological models. Organoids of the brain have been used to study neurodevelopmental disorders; intestinal organoids, to model celiac disease; and lung organoids, to investigate SARS-CoV-2. Heart organoids have even been sent to space to test the effect of microgravity on cardiac muscle. But there's a tiny problem—the organoids can't grow any bigger than a sesame seed.

2.512. Colonoscopy screening at age 45 yields neoplasia rates close to older adults: Study supports guideline change

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Researchers from Kaiser Permanente Northern California reveal that adults aged 45 to 49 undergoing their first screening colonoscopy have neoplasia detection rates similar to those aged 50 to 54, supporting recent guideline changes to begin colorectal cancer screening earlier.

2.513. Alzheimer's gene therapy shows promise in preserving cognitive function

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Researchers at the University of California San Diego School of Medicine have developed a gene therapy for Alzheimer's disease that could help protect the brain from damage and preserve cognitive function. Unlike existing treatments for Alzheimer's that target unhealthy protein deposits in the brain, the new approach could help address the root cause of Alzheimer's disease by influencing the behavior of brain cells themselves.

2.514. Algorithm reveals how a small region in our brain plays a key role in motivation

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A small region of the brain, known as the ventral tegmental area (VTA), plays a key role in how we process rewards. It produces dopamine, a neuromodulator that helps predict future rewards based on contextual cues. A team from the universities of Geneva (UNIGE), Harvard, and McGill has shown that the VTA goes even further: It encodes not only the anticipated reward but also the precise moment it is expected.

2.515. Role reversal: Millions of kids are caregivers for elders and why their numbers might grow

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Researchers estimate that there are at least 5.4 million U.S. children who provide care to an adult in their home. As state officials eye federal Medicaid funding cuts that could drastically reduce home care services for those who are disabled or have chronic health conditions, many predict that number will rise.

2.516. Turkish Airlines passenger from Denver is 7th measles case tied to DIA outbreak

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A Denver resident is the seventh Coloradan to get measles from a passenger on a Turkish Airlines flight last month—and they may have passed the highly contagious virus on to people at three stores along the Front Range.

2.517. Weight stigma—not BMI—has the biggest effect on mental health after weight-loss surgery, research indicates

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New research shows that weight stigma—and not weight itself—has the biggest impact on mental health and healthy behaviors in the years after weight-loss surgery.

2.518. Native Americans hurt by federal health cuts, despite RFK Jr.'s promises of protection

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Navajo Nation leaders took turns talking with the U.S. government's top health official as they hiked along a sandstone ridge overlooking their rural, high-desert town before the morning sun grew too hot.

2.519. Study reveals survival limits of kidney transplantation in older and high-risk patients

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A major international study presented at the 62nd ERA Congress reveals that the long-accepted survival advantage of deceased-donor kidney transplantation does not extend equally to every patient and every donor organ.

2.520. Jail time increases a person's risk of death, study reveals

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Jail time has a huge effect on both an individual's and a community's long-term health, even after their release, a new study says.

2.521. Q&A: Long-term success of GLP-1 therapies hinges on more than just a prescription

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GLP-1 (glucagon-like peptide-1) therapies can be powerful tools in managing obesity, with patients taking these medications seeing weight reductions of 5%–18% in clinical trials, along with increased metabolism and benefits to their overall heart health. However, GLP-1s can come with challenges, including gastrointestinal side effects, risk of micronutrient deficiencies, muscle and bone loss, poor long-term follow-through with weight regain if stopped, and high costs.

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