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Comprehensive genomic profiling linked to higher targeted therapy use, with Medicare patients lagging behind

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  • 2025-07-16 17:14 event
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Comprehensive genomic profiling linked to higher targeted therapy use, with Medicare patients lagging behind
Optum and Illumina Inc. researchers documented that less than half of patients with newly diagnosed advanced cancers received any biomarker testing before starting treatment, a gap that persisted despite established guidelines recommending such assessments to guide therapy selection.

1.813. Neurons use built-in 'backup batteries' that fuel the brain under stress

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A new Yale study has revealed that neurons—the energy-hungry cells that connect and direct activity in the brain—are equipped with "backup batteries" that kick in to keep the brain running during periods of metabolic stress.

1.814. AHA launches surgical quality improvement effort focused on hemorrhagic stroke treatments

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Hemorrhagic strokes account for just 13% of the nearly 800,000 strokes that occur in the U.S. each year, yet they are responsible for more than 40% of all stroke-related deaths. These devastating brain bleeds have long lacked standardized surgical treatment protocols, limiting patient recovery options.

1.815. Bee venom effects on vascular system demonstrated

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A study led by the Universitat Autònoma de Barcelona (UAB) shows that bee venom apitoxin alters the functioning of blood vessels, even at low concentrations. Researchers also identified an important molecular pathway of oxidative stress involved in this effect, which in turn opens the door to exploring its therapeutic potential.

1.816. Exercise could ease symptoms for people with chronic lymphocytic leukemia, support and guidance are lacking: Study

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Personalized exercise guidance is needed for people living with chronic lymphocytic leukemia (CLL), the most common type of blood cancer, according to a new study led by the University of Surrey.

1.817. Intensity of opioid use appears to be higher in fentanyl era

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Illegal opioids can create substantial harms, but the extent of those harms depends on multiple factors, including the amount consumed. In a new study, researchers assessed whether opioid consumption intensity varies appreciably over time or context. They found that intensity—as opposed to prevalence—of illegal opioid use varies enormously. These findings have implications for drug treatment and policy.

1.818. Protecting childhood mental health after preterm birth: Key factors identified

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Around 8% of all births in England are preterm. Despite improvements in neonatal care and survival, preterm children still have more difficulties in later life than their peers, including a higher risk of mental health problems, which have not improved in recent decades.

1.819. Depression often associated with early menopause: Why some women are at greater risk

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Premature menopause has been described as a life-changing diagnosis with profound physical, psychological, and social consequences. Affected women not only experience the effects of estrogen deficiency, but they also experience the unanticipated loss of reproductive function.

1.820. Study shows food preferences, stigma among reasons students don't eat free school meals

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During the COVID-19 pandemic, the federal government enabled schools to provide all children, regardless of need, with free meals to address nutrition and food insecurity. While program participation increased, many students declined the free meals, missing out on potential health and academic benefits.

1.821. Funding for lifesaving global health programs forecast to reach 15-year low

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After 30 years of health improvements around the world, funding cuts to global health could put lifesaving health care at risk between now and 2030, according to the latest annual report, Financing Global Health (FGH), released by the Institute for Health Metrics and Evaluation (IHME) at the University of Washington School of Medicine in Seattle.

1.822. Comprehensive genomic profiling linked to higher targeted therapy use, with Medicare patients lagging behind

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Optum and Illumina Inc. researchers documented that less than half of patients with newly diagnosed advanced cancers received any biomarker testing before starting treatment, a gap that persisted despite established guidelines recommending such assessments to guide therapy selection.

1.823. Unraveling respiratory illnesses with iPSCs on microfluidic chips

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Respiratory infections such as COVID-19 have been responsible for numerous pandemics and have placed a substantial burden on health care systems. Such viruses can cause significant damage to our lungs, especially to the proximal region, or airway, and distal region, also known as the alveoli.

1.824. Discovery of low power cellular housekeeping in human oocytes could boost IVF success

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Human eggs are some of the most patient cells in the body, lying dormant for decades until needed. A study published in The EMBO Journal shows that the cells deliberately slow the activity of their internal waste disposal systems as they mature, most likely an evolutionary design which keeps metabolism low and damage at bay.

1.825. Trove of genetic data to spur cancer research released

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In an effort to foster progress in cancer research, the National Institute of Standards and Technology (NIST) is releasing detailed and comprehensive data about the entire genetic content of a pancreatic cancer cell. Scientists can use it to research tumors, improve cancer diagnostic tests, and develop new cancer treatments.

1.826. Optimal heart health in children cuts risk of chronic diseases in adulthood, review indicates

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Optimal heart health from birth through adolescence, as measured by a combination of metrics, leads to long-lasting cardiovascular and overall physical, cognitive and mental health, according to the systematic review published in the Journal of the American Heart Association.

1.827. Research highlights unreliable responses from most Amazon MTurk users, except for 'master' workers

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A new study led by Dr. Vadim Axelrod, of the Gonda (Goldschmied) Multidisciplinary Brain Research Center at Bar-Ilan University, has revealed serious concerns about the quality of data collected on Amazon Mechanical Turk's (MTurk)—a platform widely used for behavioral and psychological research.

1.828. The secret sequence: How eye contact timing influences our social understanding

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For the first time, a new study has revealed how and when we make eye contact—not just the act itself—plays a crucial role in how we understand and respond to others, including robots.

1.829. Study finds stigma drives depression in alopecia patients, rather than illness severity

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The stigma of having alopecia causes more depression and anxiety than the disease itself, new research has found.

1.830. Yoga, Tai Chi, walking and jogging may be best forms of exercise for insomnia, data suggest

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Yoga, Tai Chi, walking and jogging may be the best forms of exercise to improve sleep quality and ease insomnia, suggest the findings of a comparative pooled data analysis published in the online journal BMJ Evidence Based Medicine.

1.831. Medical tourism for bariatric/weight reduction surgery needs urgent regulation, say experts

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Medical tourism for bariatric and weight-reduction surgery needs urgent regulation to protect recipients' health, especially as the data show that tourist numbers are increasing despite the advent of weight loss drugs, say experts in a commentary published online in BMJ Global Health.

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