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Computational tool ranks compounds to improve cancer immunotherapy effectiveness

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  • 2025-08-06 20:13 event
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Computational tool ranks compounds to improve cancer immunotherapy effectiveness
A study published in Cell Reports Medicine reports a scalable, data-driven computational framework for designing combinatorial immunotherapies, offering hope for patients with poor responses to current immunotherapies.

600. Is it true foods with a short ingredient list are healthier? A nutrition expert explains

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At the end of a long day, who has time to check the detailed nutrition information on every single product they toss into their shopping basket?

601. What your pet's poo can reveal about the spread of antibiotic-resistant superbugs

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Bagging up and disposing of your pet's poo is a necessary, albeit unpleasant, part of responsible pet ownership. But a new UK government initiative will be asking people to send them their pets' poo instead of throwing it away.

602. Mushroom-derived molecule drives microbial chemistry linked to colorectal cancer

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Microbes in our gut are important for overall health, but certain bacteria can promote inflammation, damage DNA, and support the growth of diseases like cancer.

603. Non-antibiotic drugs can also disrupt the microbiome

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Non-antibiotic drugs can alter the microbiome and increase the risk of gut infections in surprising ways, a new Nature study shows.

604. Plastics and human health: What's at stake in the global treaty talks in Geneva

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Plastics are everywhere—they're even in you right now—and are making many of us sick. Now, global negotiators are fighting over whether that matters.

605. Dual imaging capsule captures 3D tissue and blood vessel changes for early esophageal cancer diagnosis

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Researchers from Helmholtz Munich, the Technical University of Munich (TUM), and the Medical University of Vienna have developed an advanced imaging technique called "O2E" that allows clinics to detect cancerous lesions in the esophagus with unprecedented precision.

606. An estimated 17 million US youth meet criteria for GLP-1RA treatment

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A cross-sectional analysis from Yale School of Medicine estimates that approximately 5.8 million adolescents and 11.1 million young adults in the United States meet eligibility criteria for glucagon-like peptide-1 receptor agonists (GLP-1RAs), drugs approved to treat obesity and type 2 diabetes (T2D) in some pediatric populations.

607. Transcatheter edge-to-edge repair associated with improved survival in the elderly patients with blood condition

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The mitral valve controls blood flow between the heart's left atrium and ventricle. When structural changes affect the atrium or valve, it may not close fully—causing blood to leak backwards, a condition known as atrial functional mitral regurgitation (AFMR). Common in frail or elderly patients, AFMR often leads to heart failure, and standard surgery is typically too risky due to other health issues.

608. Diabetes in pregnancy and school-age developmental outcomes for offspring

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Children whose mothers had diabetes in pregnancy—gestational and pre-existing—do not have an increased risk of developmental vulnerability or lower educational outcomes, a new University of Melbourne study has found.

609. Computational tool ranks compounds to improve cancer immunotherapy effectiveness

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A study published in Cell Reports Medicine reports a scalable, data-driven computational framework for designing combinatorial immunotherapies, offering hope for patients with poor responses to current immunotherapies.

610. Boosting AI to read chest X-rays smarter and more accurately

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Scientists from CSIRO, Australia's national science agency, have developed a world-first method to teach artificial intelligence (AI) how to write more accurate chest X-ray reports by giving it the same information doctors use in real life.

611. Expanding access to sickle cell gene therapies for patients with Medicaid

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Connecticut is now participating in a new federal program aimed at expanding treatment access for patients with sickle cell disease who are insured through Medicaid.

612. New study highlights critical role of calcium monitoring in pre-hospital trauma care

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A new study conducted across five U.K. air ambulance services has revealed significant variation in calcium levels among trauma patients receiving pre-hospital blood transfusions—highlighting a critical opportunity to provide more tailored care for patients.

613. Tribal groups assert sovereignty as feds crack down on gender-affirming care

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At the Two Spirit Conference in northern Nevada in June, Native Americans gathered in support of the LGBTQ+ community amid federal and state rollbacks of transgender protections and gender-affirming health care.

614. Experts urge physiology-based strategies to protect people during deadly heat waves

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When the human body overheats, the consequences can be deadly. Heat stroke, heart attacks, kidney failure, and worsening of existing conditions like cardiovascular and respiratory diseases are just some of the ways extreme heat can push the body past its limits.

615. Study reveals placental inflammation as the cause of allergic diseases such as pediatric asthma

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It is already well known that when a mother experiences inflammation during pregnancy, her child is more likely to develop allergic diseases. Recently, a KAIST research team became the first in the world to discover that inflammation within the placenta affects the fetus's immune system, leading to the child exhibiting excessive allergic reactions after birth.

616. Harm reduction techniques being phased out under Trump

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The Trump administration is escalating its push against what has become a key part of the way states, localities and communities respond to the overdose epidemic: harm reduction.

617. Fear of hair loss might cause some to reject cancer treatment

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Needless fear of hair loss and brittle, discolored nails caused by cancer treatment might lead many patients to avoid or delay life-saving treatment, a new pilot study says.

618. New European toolkit launched to help eliminate hepatitis in prisons

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The new toolkit is designed to support the implementation and scale-up of hepatitis B and C interventions in prisons across Europe. It also reinforces the principle of "equivalence of care," ensuring that people in prison receive health care comparable to that available in the community.

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