Crown jewel of dental restoration technology may be in sight with 3D printing

Researchers at UMC Utrecht have discovered that converting monoclonal antibodies from the IgG to the IgM isotype can significantly broaden their ability to recognize and bind multiple human-relevant bacterial pathogens. The study is published in Cell Reports Medicine.

Sound waves at frequencies above the threshold for human hearing are routinely used in medical care. Also known as ultrasound, these sound waves can help clinicians diagnose and monitor disease, and can also provide first glimpses of your newest family members.

Researchers from the Universitat Autònoma de Barcelona (UAB) have published an analysis that reveals new functions of the RAD21L protein—a germline-specific cohesin—crucial for male fertility. The study, carried out in mice and in collaboration with the Spanish National Research Council (CSIC), the University of Salamanca, and the National Center for Genomic Analysis (CNAG) of Barcelona, is published in the journal Science Advances.

RNA sequencing (RNA-seq) is a powerful tool in diagnosing Mendelian disorders, but the optimized sequencing depth for this technology has not yet been determined. In a new study published in the American Journal of Human Genetics, researchers at Baylor College of Medicine's Medical Genetics Multiomics Laboratory (MGML) show the utility and benefit of ultra-deep RNA sequencing in clinical diagnostics.

The effectiveness of eye-tracking technology in identifying people who have a genetic tendency to Alzheimer's disease, years before their symptoms show, has been highlighted in new research.

A new study led by USC Rossier School of Education Professor Brendesha Tynes, and published in JAMA Network Open, reveals that Black adolescents in the U.S. experience an average of six race-related online encounters every day, including three instances of online racism. These daily experiences, from algorithmic bias to traumatic event videos, are linked to increased symptoms of anxiety and depression the next day.

Mutations in a gene known as CPD play a crucial role in a rare form of congenital hearing loss, an international team of researchers has discovered.

Using fruit flies, University of Wisconsin–Madison researchers have developed a new model for investigating the genetic drivers of a rare but aggressive brain tumor in children. The work has already identified potential treatment targets for the deadly cancer that has previously had few therapeutic options.

Using fruit flies, University of Wisconsin–Madison researchers have developed a new model for investigating the genetic drivers of a rare but aggressive brain tumor in children. The work has already identified potential treatment targets for the deadly cancer that has previously had few therapeutic options.

Opening new gun stores may raise neighborhood shooting rates for years, highlighting how firearm availability affects community violence, according to Rutgers researchers.

It's nearly midnight on a school night. Your teenager's light is still on. Maybe they're finishing homework, scrolling through social media, or texting friends.

"You look so great! Have you lost weight?"

When we form a memory, brain cells need to deliver supplies to strengthen specific neural connections. A new study from MPFI and Weill Cornell Medicine has revealed how two cellular switches, Rab4 and Rab10, direct supplies to where they are needed. The findings are published in the journal eLife.

When doctors analyze a medical scan of an organ or area in the body, each part of the image has to be assigned an anatomical label. If the brain is under scrutiny, for instance, its different parts have to be labeled as such, pixel by pixel: cerebral cortex, brain stem, cerebellum, etc. The process, called medical image segmentation, guides diagnosis, surgery planning and research.

Many of us go to the gym to bulk up. But how does it actually work?

How is it that we all see the world in a similar way? Imagine sitting with a friend in a café, both of you looking at a phone screen displaying a dog running along the beach. Although each of our brains is a world unto itself, made up of billions of neurons with completely different connections and unique activity patterns, you would both describe it as: "A dog on the beach." How can two such different brains lead to the same perception of the world?

As your youth fades further into the past, you may start to fear growing older.

Medication has long been the cornerstone of treatment for people with epilepsy, but it doesn't stop seizures for everyone and may come with significant side effects. New options in use or under development include devices and gene and cell therapies aimed at resetting or rehabilitating the brain circuits that cause seizures, explains Dr. Jonathon Parker, a neurosurgeon at Mayo Clinic in Phoenix and director of the Device-Based Neuroelectronics Research Lab.