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Current diagnostic tool underestimates kidney failure risk in frail individuals, finds study

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  • 2025-08-08 23:13 event
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Current diagnostic tool underestimates kidney failure risk in frail individuals, finds study
Researchers have found that a common tool used by clinicians for predicting kidney failure could be underestimating the risk of failure for some people. The study, "Frailty in Adults with Chronic Kidney Disease and Validation of the Kidney Failure Risk Equation in Frailty Sub-Groups," is published in the Clinical Journal of the American Society of Nephrology.

414. Study maps intricate muscle patterns behind blinking and eyelid movement

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A blink of an eye seems natural and instantaneous, but is it? Without a functioning eyelid, the eye can become dry, irritated and eventually lose the ability to see clearly.

415. Genomics-guided tool helps guide immunotherapy choices for advanced kidney cancers

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A study led by Roswell Park Comprehensive Cancer Center helps explain why a rare and hyper-aggressive subtype of kidney cancer is susceptible to immunotherapy—information that helped researchers create a first-of-its-kind tool to guide treatment decisions for advanced kidney cancers.

416. Study shows people overestimate hill steepness based on their eye level

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People's perceptions of the world are easily impacted by the angle at which they view objects in it, suggests a new study.

417. Did you walk or cycle to school as a child? Your children are likely to follow in your footsteps

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If you used physically active modes of commuting to school, your children are likely to do the same. A study published in the European Journal of Public Health by the University of Jyväskylä, Finland, reveals an intergenerational link between parents' and their children's school commuting habits. The researchers emphasize that active commuting to school is a simple and practical way to incorporate more physical activity into daily life.

418. User-friendly tool streamlines transcriptomic data analysis for precision medicine applications

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The Barcelona Institute for Global Health (ISGlobal) has launched HTGAnalyzer, a new, easy-to-use, fast and reproducible bioinformatics tool for advanced transcriptomic data analysis. Designed within the R statistical environment, this package simplifies complex analytical processes, making them accessible to professionals without specific expertise in bioinformatics.

419. Report ties to child mental health crisis to immigration enforcement

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Aggressive immigration practices—such as detention, deportation, and workplace raids—are contributing to widespread emotional trauma among both immigrant and U.S.-born children living in mixed-status households, according to a report published by a team of mental health professionals in the School of Medicine at the University of California, Riverside.

420. An alternative to injections: New weight loss pill shows promise in early study

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A new weight loss pill made by Eli Lilly helped people lose a significant amount of weight in a recent study.

421. CDC warns travelers after 8,000+ chikungunya cases reported in China

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Health officials in China are reporting more than 8,000 cases of chikungunya, a virus spread by mosquitoes that can cause fever and painful joints.

422. Multicenter trial confirms near-infrared autofluorescence increases detection of parathyroid glands

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A team led by Vanderbilt University and Vanderbilt University Medical Center biomedical engineers and surgeons has published results of a large clinical trial showing that use of a near-infrared autofluorescence (NIRAF) probe device improves intraoperative identification of parathyroid glands (PGs).

423. Current diagnostic tool underestimates kidney failure risk in frail individuals, finds study

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Researchers have found that a common tool used by clinicians for predicting kidney failure could be underestimating the risk of failure for some people. The study, "Frailty in Adults with Chronic Kidney Disease and Validation of the Kidney Failure Risk Equation in Frailty Sub-Groups," is published in the Clinical Journal of the American Society of Nephrology.

424. Targeting sleeping tumor cells: Oncogene location may determine neuroblastoma's resistance to cancer therapy

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Neuroblastoma can be a particularly insidious cancer. In about half of all cases, tumors regress, even without therapy. In the other half, tumors grow very quickly. These tumors often respond well to chemotherapy at first, but usually return after one to two years. A characteristic feature of such aggressive neuroblastoma cells is an abnormally high number of copies of the oncogene MYCN.

425. AI scribes gain traction among New Zealand GPs despite ethical and legal concerns

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Many New Zealand GPs have taken up the use of AI scribes to transcribe patient notes during consultations despite ongoing challenges with their legal and ethical oversight, data security, patient consent, and the impact on the doctor-patient relationship, a study led by the University of Otago, Wellington—Ōtākou Whakaihu Waka, Pōneke has found.

426. 'A tipping point': Expert gives update from frontiers of Alzheimer's disease research

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One-third of people older than 85 in the United States are estimated to live with Alzheimer's disease today, according to the National Institute on Aging. The condition's characteristic long, slow decline places an enormous burden on families and on society. While the need for new treatments is urgent, Alzheimer's is a complex disease that requires multidisciplinary research across a wide range of specialties.

427. Mathematical models help correct errors in MRI brain blood flow imaging

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A team led by Eamon Doyle, Ph.D., in the Borzage Laboratory at Children's Hospital Los Angeles developed novel computational models for magnetic resonance imaging. These models enable more accurate imaging of cerebral blood flow in children and adults while compensating for missing imaging data.

428. Mobile phone app reduces suicidal behavior among high-risk patients, new study shows

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A mobile phone app designed to deliver suicide-specific therapy reduced suicidal behavior among high-risk psychiatric inpatients, according to a new study by scientists at Yale School of Medicine and The Ohio State University Wexner Medical Center and College of Medicine.

429. Study of surgical interventions for children, adolescents with kidney stones supports precision treatment options

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Researchers at Children's Hospital of Philadelphia (CHOP), along with several academic partners, have reported the primary results of the Pediatric KIDney Stone (PKIDS) trial, the largest comparative effectiveness study of surgical interventions for children and adolescents with kidney stones.

430. What to say and how to help if someone close to you has attempted suicide

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If someone close to you has attempted suicide, you may be feeling scared, confused or overwhelmed.

431. The food is medicine movement needs a lesson in equity, say researchers

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A new editorial, led by faculty members at UC Irvine Joe C. Wen School of Population & Public Health appears in the American Journal of Public Health and urges the "Food is Medicine" (FIM) movement to course-correct—warning that without broader access strategies, it risks leaving behind the very people it aims to help.

432. Wearable blood pressure monitor attaches like a bandage for real-time continuous measurement

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Seoul National University College of Engineering announced that a research team has developed a wearable electronic device that attaches to the skin like a bandage and enables real-time, continuous monitoring of blood pressure over extended periods.

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