Discovery of DIAL syndrome links faulty DNA repair to childhood cancer risk and chemo sensitivity

A research team from the School of Clinical Medicine of the LKS Faculty of Medicine of the University of Hong Kong (HKUMed) has pioneered the use of a 'dual immunotherapy' combination—nivolumab and ipilimumab (NIVO+IPI)—in the treatment of liver cancer patients since 2016.

Alcohol advertising is everywhere—on TV, bus shelters, and social media. As a parent, keeping track of what your child sees can seem impossible. So, should we be concerned about children being exposed to alcohol ads?

Type 1 diabetes (T1D) is an autoimmune condition where the immune system destroys insulin-producing β-cells in the pancreas. Yet, not all patients lose insulin function at the same pace. Understanding this variation is especially important in Japanese populations, who tend to experience faster and more complete loss of insulin secretion than their Western counterparts.

A video consultation between patient and surgeon is just as good as a physical visit to the outpatient clinic to discuss a major operation. This is evident from research by Amsterdam UMC, which demonstrated that a video consultation is just as good as a physical consultation in terms of information uptake.

Nearly one in four U.S. adults over the age of 65 have diabetes. Older veterans are highly impacted by this disease, due in part to risk factors incurred during their military service, such as exposure to Agent Orange and posttraumatic stress disorder (PTSD). Diabetes requires active and ongoing daily self-management and increases the risk of developing other chronic health conditions, which negatively impact functioning and disability.

First described 60 years ago, chronic myoclonus following cerebral anoxia is now known as Lance-Adams syndrome. This is a severe disorder whose mechanisms were, until now, poorly understood. Geoffroy Vellieux, Vincent Navarro, and their colleagues at the Paris Brain Institute now show that this condition originates in the motor cortex. Their findings are published in the journal Neurology.

A recent study led by the University of Turku, Finland, analyzed the DNA map of more than 14,000 gut metagenomes in a global dataset and found that there are differences in antibiotic resistance between genders. In high-income countries, women had more antibiotic resistance genes than men.

The brain is constantly mapping the external world like a GPS, even when we don't know about it. This activity comes in the form of tiny electrical signals sent between neurons—specialized cells that communicate with one another to help us think, move, remember and feel. These signals often follow rhythmic patterns known as brain waves, such as slower theta waves and faster gamma waves, which help organize how the brain processes information.

Texas has moved to fund research into ibogaine, a psychedelic drug that may help treat addiction, depression and brain injuries.

The American College of Obstetricians and Gynecologists is urging insurers to continue covering vaccinations during pregnancy in an open letter signed by 30 prominent professional health organizations.

A new study led by researchers at University of Iowa Health Care has revealed a significant association between high blood pressure during pregnancy (gestational hypertension) and an increased risk of seizures in children.

Accidents occurring in the home are a substantial cause of non-fatal injuries requiring medical care in low- and middle-income countries (LMICs)—with women disproportionately affected, a new study reveals.

You stayed up too late scrolling through your phone, answering emails or watching just one more episode. The next morning, you feel groggy and irritable. That sugary pastry or greasy breakfast sandwich suddenly looks more appealing than your usual yogurt and berries. By the afternoon, chips or candy from the break room call your name. This isn't just about willpower. Your brain, short on rest, is nudging you toward quick, high-calorie fixes.

Your brain makes insulin—the same insulin produced by your pancreas. The same insulin that is not produced in people with type 1 diabetes and the same insulin that does not work properly in people with type 2 diabetes.

A multidisciplinary team led by Professor Li Yulong from the School of Life Sciences at Peking University has developed a far-red fluorescent dopamine (DA) probe that enables real-time, multiplex imaging of neurotransmitters in the living brain.

Deep-brain imaging in awake mice reveals how light resets the circadian clock by activating complex SCN neuron networks.

Two existing medications—one used for smoking cessation and the other for depression—appear to work effectively together in treating alcohol use disorder. The combination reduces alcohol cravings, lowers consumption, and may decrease the risk of nausea. These findings come from a new study led by the University of Gothenburg, Sweden.

Australian researchers have demonstrated that the use of a new, less toxic drug combination after stem cell transplants for leukemia significantly improves patient outcomes post-transplant, reducing the risk of the life-threatening complication of graft versus host disease (GVHD).