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Early neuroinflammation in people with Down syndrome may explain high prevalence of Alzheimer's disease

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  • 2025-10-03 03:57 event
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Early neuroinflammation in people with Down syndrome may explain high prevalence of Alzheimer's disease
Down syndrome is associated with accelerated aging. It is estimated that up to 90% of individuals with the condition develop Alzheimer's disease before the age of 70. A study by researchers at the University of São Paulo (USP) in Brazil identified high levels of neuroinflammation in young individuals with Down syndrome, an additional factor explaining the high prevalence of Alzheimer's disease in older people with the condition. The discovery paves the way for strategies to prevent and monitor the disease.

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1. Early medical abortion at home up to 12 weeks found to be safe, effective, comparable to hospital care

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Early medical abortion at home up to 12 weeks of pregnancy is safe, effective, and comparable to hospital care, finds a five-year review of cases in Scotland, where this timeframe is legally permitted. The review was published online in the journal BMJ Sexual & Reproductive Health.

2. Countries with highest reported levels of hearing loss also have lowest use of hearing aids, research finds

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Countries with the highest reported levels of hearing loss also have the lowest reported use of hearing aids, finds international research published in the open access journal BMJ Global Health.

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4. Early neuroinflammation in people with Down syndrome may explain high prevalence of Alzheimer's disease

  • 3 hours ago schedule
  • medicalxpress.com language

Down syndrome is associated with accelerated aging. It is estimated that up to 90% of individuals with the condition develop Alzheimer's disease before the age of 70. A study by researchers at the University of São Paulo (USP) in Brazil identified high levels of neuroinflammation in young individuals with Down syndrome, an additional factor explaining the high prevalence of Alzheimer's disease in older people with the condition. The discovery paves the way for strategies to prevent and monitor the disease.

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