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Elucidated protein structures in the malaria parasite offer opportunities for new vaccines

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  • 2025-10-09 22:00 event
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Elucidated protein structures in the malaria parasite offer opportunities for new vaccines
Using millions of microscope images magnified up to 130,000 times, researchers from Radboud University Medical Center and Toronto have unraveled the structure of two key proteins in the malaria parasite. With this knowledge, scientists are developing new vaccines that block the transmission of parasites via mosquitoes.

38. System can detect genetic mutations in brain tumors during surgery in just 25 minutes

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A research team in Japan has developed an innovative system that can accurately detect genetic mutations in brain tumors within just 25 minutes. Genetic mutations are crucial markers for diagnosis of brain tumors.

39. Vitamin A transporter reactivates latent HIV, providing another step towards a cure

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Human immunodeficiency viruses (HIV) are insidious. They can evade the immune defense and antiviral drugs by becoming "latent." In this state, they are largely invisible and unassailable. As long as these dormant viruses persist, there is no cure for HIV/AIDS. However, researchers at Ulm University Hospital have discovered a new way to reactivate latent HI viruses. This is made possible by the body's own protein RBP4, a transporter for vitamin A—and provides a new starting point for HIV cure approaches.

40. Sno Pac recalls frozen spinach sold across the US

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A Minnesota-based company is recalling two types of organic frozen spinach sold nationwide because they may be contaminated with Listeria, a bacteria that can cause serious or even life-threatening illness.

41. Newborn genomic screening can enable more lifesaving diagnoses

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Adding genomic sequencing to newborn blood screening would detect hundreds of additional childhood conditions, providing much earlier diagnosis and treatment, according to a new study. A baby's genome, which stays with them for life, could also be re-examined if a health issue arises during their lifetime.

42. Congo's war cuts off medicine to hundreds of health facilities

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More than 200 health centers in eastern Congo are running out of essential medicine due to ongoing fighting and a lack of humanitarian aid, the International Committee of the Red Cross (ICRC) warned.

43. Implicit bias impacts how autistic and non-autistic people exert 'charitable' effort

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Societal stigma against autistic people may influence how much effort individuals put into 'prosocial' or charitable behaviors, according to a new study.

44. Cyberdelics: Immersive VR visual hallucinations simulate effects of psychedelic substances

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Immersive virtual reality experiences can reproduce visual hallucination effects, miming those induced by the use of psychedelic substances.

45. Nanoparticle vaccine prevents multiple cancers and stops metastasis in mice

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A study led by University of Massachusetts Amherst researchers demonstrates that their nanoparticle-based vaccine can effectively prevent melanoma, pancreatic and triple-negative breast cancer in mice. Not only did up to 88% of the vaccinated mice remain tumor-free (depending on the cancer), but the vaccine reduced—and in some cases completely prevented—the cancer's spread.

46. Novo Nordisk buys US biotech firm Akero for $4.7 billion

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Novo Nordisk said Thursday it was buying US biotech firm Akero Therapeutics, which is developing treatments for a number of metabolic diseases, for $4.7 billion.

47. Elucidated protein structures in the malaria parasite offer opportunities for new vaccines

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Using millions of microscope images magnified up to 130,000 times, researchers from Radboud University Medical Center and Toronto have unraveled the structure of two key proteins in the malaria parasite. With this knowledge, scientists are developing new vaccines that block the transmission of parasites via mosquitoes.

48. Nuclear missile workers are contracting cancer: They blame the bases

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At a memorial service in 2022, veteran Air Force Capt. Monte Watts bumped into a fellow former Minuteman III nuclear missile operator, who told him that she had non-Hodgkin lymphoma.

49. Study identifies distinct profiles of nonverbal learning disability, offering fresh insights for diagnosis and care

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A study published in JAMA Network Open identifies four distinct profiles of Nonverbal Learning Disability (NVLD), providing evidence that may help refine diagnostic criteria and guide more individualized approaches to care for children and families.

50. Workers' wages siphoned to pay medical bills, despite consumer protections

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Stacey Knoll thought the court summons she received was a scam. She didn't remember getting any medical bills from Montrose Regional Health, a nonprofit hospital, after a 2020 emergency room visit.

51. Specialized cell discovery could improve type 1 diabetes prevention and treatment

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Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks the cells that produce insulin—a critical hormone that regulates blood sugar in the body. Scientists at Scripps Research have discovered a new kind of cell that helps protect insulin production, paving the way to understanding how researchers could prevent or reverse type 1 diabetes.

52. Postmortem brain study finds way to correct for decay effects when looking for schizophrenia footprint

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Skoltech researchers have investigated the way the composition of small molecules called lipids and metabolites varies in the brain in the first hours and days after death.

53. Study suggests air pollution can contribute to obesity and diabetes

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Long-term exposure to fine air pollution can impair metabolic health by disrupting the normal function of brown fat in mice. A study co-led by the University of Zurich shows that this occurs through complex changes in gene regulation driven by epigenetic mechanisms. The results demonstrate how environmental pollutants contribute to the development of insulin resistance and metabolic diseases.

54. Restless leg syndrome's connection to Parkinson's disease

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Three research hospitals in the Republic of Korea are reporting that restless leg syndrome was associated with an increased risk of Parkinson's disease, with 1.6% of patients with restless leg syndrome developing Parkinson's disease vs. 1.0% in matched controls and a shorter average time to diagnosis at a 15-year horizon.

55. How employers can promote physical activity among workers: Three messages based on research

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We all know about the benefits of physical activity—not just to reduce the risks of chronic disease and physical injuries but also to improve mental health and productivity at work. But many people just don't get as much physical activity as they should.

56. Why do some songs get stuck in our heads so easily? The science of earworms

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If you've watched the movie KPop Demon Hunters and see the word "golden," what happens?

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