Evaluating the impact of hormone therapy on the athletic performance of transgender women athletes

In a scientific first, researchers have decoded a naturally acquired antibody directly from the blood of a child exposed to malaria. Using advanced mass spectrometry, the team identified an antibody that blocks a critical interaction between the parasite Plasmodium falciparum and human blood vessels—a step central to the development of severe malaria.

Research led by investigators at Mass General Brigham suggests that the health benefits of more aggressive blood pressure control outweigh concerns about overtreating people with high blood pressure readings. Results of the simulation study are published in Annals of Internal Medicine.

A research team led by Indiana University School of Medicine physician scientists has made significant progress in mapping kidney cells that may one day allow for more accurate disease diagnosis.

One in five children in the United States has obesity, which is a significant predictor of chronic health problems later in life.

A new study published in The Annals of Thoracic Surgery, has identified early hemodynamic valve deterioration (HVD) in more than 6% of patients just one year after undergoing transcatheter aortic valve implantation (TAVI), raising new questions about valve durability in younger, lower-risk populations.

Studying families with multiple members who had breast cancer first led to the discovery of mutations in BRCA genes. Doctors have since learned that these mutations increase the risk of developing multiple tumor types, including breast, ovarian, pancreatic and prostate cancers.

A newly published clinical study reveals a potential breakthrough in the treatment of refractory postpartum hemorrhage (PPH), the leading cause of maternal death worldwide.

Reproductive timing matters when it comes to aging and age-related disease. In a study now online at eLife, Buck Institute for Research on Aging researchers have determined that girls who go through puberty (the onset of menstruation) before the age of 11 or women who give birth before the age of 21 have double the risk of developing type 2 diabetes, heart failure and obesity and quadruple the risk of developing severe metabolic disorders.

Alzheimer's disease steals memories and devastates lives. Yet despite an abundance of research, the earliest brain changes that trigger this disease still remain unclear, making it challenging to find effective treatments.

A cornerstone of 19th century welfare reform, the 1834 Poor Law Amendment Act, had a devastating impact on child health and rural life expectancy in England and Wales, says a new study.

Research in the International Journal of Human Factors and Ergonomics has examined outpatient prescribing and found that overworked pharmacists as well as systemic workplace flaws can lead to dispensing errors. According to the World Health Organization (WHO), such errors remain a major and preventable cause of patient harm worldwide.

England has entered its fourth heat wave of 2025. Historical comparisons for our current weather situation have seemed to beach at 1976.

A surge in cases of a deadly flesh-eating bacteria that thrives in warm seawater is a chilling reminder of the potential danger associated with vacation pastimes like swimming and wading.

The mitochondria may be the powerhouse of the cell, but mounting evidence suggests this organelle is also a driving force behind cancer. Now, new evidence points to the mitochondrial metabolite glutathione, highlighting its central role in helping breast cancer cells break away from the primary tumor, travel through the body, and take root in other tissues.

The body's cells change their shape to close gaps such as wounds—with part of the cell flexing depending on the curve of the gap and the organization of cell-internal structures, a new study reveals.

A study co-led by researchers at The Hospital for Sick Children (SickKids) and the University of Toronto's Temerty Faculty of Medicine has uncovered why some very-high-risk brain tumors are resistant to radiation—and identified a promising new strategy to overcome it.

Globally, rapidly aging populations give rise to increasing demand for home care services. The World Health Organization estimates that approximately 1.3 billion people worldwide require care due to aging or disability. In Hong Kong, due to rising health care costs and deeply rooted cultural norms that emphasize family bonding, caregiving is often performed by family members, which imposes heavy physical and mental strain.

Two studies led by Johns Hopkins Kimmel Cancer Center, Ludwig Center, and Johns Hopkins Whiting School of Engineering researchers report on a powerful new method that significantly improves the reliability and accuracy of artificial intelligence (AI) for many applications. As an example, they apply the new method to early cancer detection from blood samples, known as liquid biopsy.