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Wiring up the brain's trillions of circuit connections is an enormous job performed by a huge crew of molecules. Among the less understood members are circular RNAs, transcripts from DNA that assume a closed loop shape. A study by a team of neuroscientists centered at MIT shows that one such circular RNA from the Homer gene (circHomer1) takes on a significant and somewhat surprising role in how the developing brains of mice form connections (synapses) in the visual system.
A study published in Science reveals a cellular mechanism involved in the inheritance of genetic mutations. The study also points to a potential treatment that could reduce the risk of babies being born with serious, incurable mitochondrial diseases.
Oral cancer remains a serious health concern, often diagnosed too late for effective treatment, even though the mouth is easily accessible for routine examination. Dentists and dental hygienists are frequently the first to spot suspicious lesions, but many lack the specialized training to distinguish between benign and potentially malignant conditions.
As our hair goes gray and our muscles weaken with age, our immune system also changes. In particular, the stem cells that become blood or immune cells can develop mutations, potentially leading to cancers or other dysfunctions.
Patients with chronic hepatitis B (CHB) have an increased prevalence of chronic kidney disease (CKD), according to a study published online Oct. 14 in BMC Gastroenterology.
In cancer patients, the health of the thymus—a key part of the body's immune system—is associated with the outcomes these patients experience after immune checkpoint inhibitor treatment, according to an international study reported at ESMO 2025.
Gov. Gavin Newsom recently signed a bill to fast-track the study of psychedelic drugs, which a coalition of veterans say hold enormous potential to treat post-traumatic stress disorder and depression.
Population-based estimates of cumulative breast cancer risk for established pathogenic variants (PVs) vary by family history and potentially modifiable risk factors, according to a study published online Oct. 9 in JAMA Oncology.
A new study from NYU Tandon, NYU Langone Health, and the NYU Stern School of Business offers one of the first data-driven looks at how generative AI might help health care providers manage their message overload—and why many are hesitant to adopt the technology.
Food processing takes many forms, and most foods are processed in one way or another—by grinding, pasteurization or fermentation. People don't want to eat unprocessed wheat—they want to eat bread. Moreover, bread, yogurt, cheese, and cured sausages such as salami are all fermented using fungal or bacterial cultures.
Voluntary assisted dying is being debated in the Northern Territory (NT) parliament this week.
A research team at the Seville Biomedical Institute (IBis) has identified a new molecular mechanism that explains the high sensitivity of Ewing sarcoma (an aggressive bone cancer that mainly affects children and adolescents) to certain chemotherapy drugs, such as irinotecan. The results, published in the journal Oncogene, open the door to more personalized and effective strategies for treating this type of cancer.
A clinical trial from Wake Forest University School of Medicine shows that two widely available medications, the diabetes drug empagliflozin (Jardiance) and intranasal insulin, safely improve brain health in people with mild cognitive impairment and early Alzheimer's disease.
In recent years, Americans have gotten used to logging on to a patient portal through their smartphone or computer to have telehealth appointments with their doctors and health care teams, see their prescriptions and lab test results, send messages to their providers, and much more.
A research team has resolved a 50-year-old controversy in neuroscience. By employing a self-developed, time-resolved cryo-electron tomography (cryo-ET) technique, the team, led by Prof. Bi Guo-Qiang from the University of Science and Technology of China (USTC) of the Chinese Academy of Sciences (CAS), in collaboration with several domestic and international institutions, has delineated the intricate choreography of synaptic vesicle (SV) release and rapid recycling, the cornerstone of neural communication.
Sleep-like slow-wave patterns persist for years in surgically disconnected neural tissue of awake epilepsy patients, according to a study published in PLOS Biology by Marcello Massimini from Universita degli Studi di Milano, Italy, and colleagues.
As more states restrict clinician-managed abortion in the wake of Dobbs v. Jackson Women's Health Organization, the Supreme Court decision that overturned Roe v Wade in 2022, more patients are pursuing self-managed medication abortion (SMMA). Definitions of SMMA can vary, but SMMA typically refers to the use of mifepristone and/or misoprostol to induce abortion outside of a clinical context. Despite the 97% completion rate and excellent safety record of a medication abortion, patients who pursue SMMA sometimes experience symptoms that prompt them to visit an emergency department or primary care clinic for evaluation.
Preschool children with more backyard space and those who live closer to parks and water do more active play than children from other neighborhoods, according to a new study by The Kids Research Institute Australia.
A Northwestern Medicine study has revealed a key mechanism underlying the development of motor neuron diseases, offering new insights into potential treatment options, according to a study published in the Journal of Neuroscience.