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FDA approves Zynyz as first-line treatment for advanced anal cancer

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  • 2025-05-22 04:07 event
  • 2 months ago schedule
FDA approves Zynyz as first-line treatment for advanced anal cancer
The U.S. Food and Drug Administration has approved the humanized monoclonal antibody Zynyz (retifanlimab-dlwr) as the first first-line treatment for advanced anal cancer.

2.510. 'It's rare and it's scary.' Dark spot on your fingernail could mean cancer

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If you are staring at a dark spot under your fingernail, you may want to see a dermatologist. It could be a form of melanoma.

2.511. Even where abortion is still legal, many brick-and-mortar clinics are closing

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On the last day of patient care at the Planned Parenthood clinic in Marquette, Michigan, a port town on the shore of Lake Superior, dozens of people crowded into the parking lot and alley, holding pink homemade signs that read "Thank You!" and "Forever Grateful."

2.512. Can Australian nurses really be ready for anything?

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Australian nurses have responded to hundreds of disaster events over the last six years, but new research led by Charles Darwin University (CDU) suggests they still aren't ready for the impact of catastrophe. The work is published in the journal Health Emergency and Disaster Nursing.

2.513. Study finds rugby players' brains are affected by concussion after being cleared to play

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Grassroots rugby concussion guidelines need to be improved as players' brains remain altered despite them being symptom-free and cleared to play, researchers have found.

2.514. Pandemic predictions that promised certainty—and delivered confusion: What we must learn

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In the early months of 2020, a curious thing happened. Around the globe, a new kind of number began appearing in government briefings and newspaper headlines. These weren't just case counts or hospital admissions. They were predictions—curves plotted weeks into the future, graphs that told us when the COVID-19 wave would crest, how many ICU beds we'd need, and how soon we'd be safe again. The models had arrived.

2.515. Antidepressant withdrawal symptoms more common among long-term users, study finds

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People who have been taking antidepressants for more than two years are substantially more likely to experience withdrawal symptoms compared to short-term users when they come off the medication, finds a new study led by UCL researchers.

2.516. Positive mindset about aging in over-60s linked to better recovery after a fall

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There is a strong association between an older person's view of how they are aging and how well they will physically recover after a fall.

2.517. Brain molecule provides new insights into migraine-related light sensitivity

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Scientists in the U.K., Australia and China have identified a brain molecule called NEAT1 that appears to play a central role in triggering light sensitivity (photophobia), a common and debilitating symptom of migraines. Their findings, published in The Journal of Headache and Pain, highlight how this molecule affects the brain's pain response, contributing to the uncomfortable reaction to light that's common during migraines.

2.518. Tumor-related epilepsy not a strong prognostic factor in diffuse glioma, finds study

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For patients with diffuse gliomas, tumor-related epilepsy (TRE) is not a strong prognostic factor, according to a study published in the May issue of Brain and Behavior.

2.519. FDA approves Zynyz as first-line treatment for advanced anal cancer

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The U.S. Food and Drug Administration has approved the humanized monoclonal antibody Zynyz (retifanlimab-dlwr) as the first first-line treatment for advanced anal cancer.

2.520. Study highlights disparities in access to advanced life support

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Use of extracorporeal membrane oxygenation (ECMO) continues to rise, but this advanced form of life support is often not provided to patients equitably. Now, new research published at the ATS 2025 International Conference has confirmed that disadvantaged patients are less likely to receive ECMO, even though they live closer to hospitals that offer it.

2.521. Classifying older adults requiring long-term care into five groups and clarifying their prognosis

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Older adults requiring long-term care frequently experience multiple disabilities, with considerable variation in the combinations of these impairments. Because of this diversity, interventions that focus on a single impairment may not be sufficient. Therefore, understanding the complex physical and cognitive conditions of older adults in need of care is essential for developing appropriate interventions.

2.522. Study uncovers link between pathogen adaptation and autoimmune diseases in Han Chinese

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A new study led by Profs. Xu Tao and He Shunmin from the Institute of Biophysics of the Chinese Academy of Sciences has revealed how human leukocyte antigen (HLA) genes, central to the immune system, influence both pathogen resistance and susceptibility to autoimmune diseases.

2.523. 'Groovy' brains may be more efficient

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Many grooves and dimples on the surface of the brain are unique to humans, but they're often dismissed as an uninteresting consequence of packing an unusually large brain into a too-small skull.

2.524. Urban areas in Missouri have higher rates of high-dose opioid prescriptions, study finds

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Researchers from the University of Missouri School of Medicine have shed light on which populations are more likely to be prescribed a high dose of opioid medication. This increases their risk of developing opioid use disorder.

2.525. Drug candidate holds promise for difficult-to-treat heart disease

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A study led by a physician-scientist at the University of Arizona College of Medicine–Tucson's Sarver Heart Center identified a drug candidate that appears to reverse the progression of a type of heart failure in mouse models, which could lead to expanded treatment options for humans. The results are published in the journal Cell Metabolism.

2.526. Gene variant linked to higher risk of long COVID symptoms

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An international team of researchers has found a genetic link to long-term symptoms after COVID-19. The identified gene variant is located close to the FOXP4 gene, which is known to affect lung function. The study, published in Nature Genetics, was led by researchers at Karolinska Institutet in Sweden and the Institute for Molecular Medicine in Finland.

2.527. Opening Remarks by DR HANAN BALKHY REGIONAL DIRECTOR WHO EASTERN MEDITERRANEAN REGION 62nd Arab ...

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19 May 2025 Excellencies, Distinguished Colleagues, It is an honour to join you today, and I thank His Excellency the Chair―Dr Saleh al-Hasnawi, Minister of Health of the Republic of Iraq―for this

2.528. How the placebo effect tricks the mind into relieving pain

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The detailed mechanism of how the placebo effect reduces the perception of pain in rats has been uncovered by RIKEN neuroscientists. These findings, published in Science Advances, could potentially lead to ways to harness the placebo effect in therapy.

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