Fast walking linked to lower lung cancer risk: A simple health indicator for cancer prevention

Imagine you are developing antibodies—drugs precisely aimed at a target, for example a viral protein or onco-marker. You test a series of antibodies and find that some work, while others do not.

Mobile integrated health (MIH) can help heart failure patients transition from the hospital to home, and may offer additional benefits to women and younger patients, say Columbia Nursing researchers in a report in JAMA Internal Medicine.

A study published in JCO Clinical Cancer Informatics demonstrates that machine learning models incorporating patient-reported outcomes and wearable sensor data can predict which patients with non–small cell lung cancer are most at risk of needing urgent care during treatment. The study was led by researchers and clinicians at Moffitt Cancer Center.

A landmark international study has revealed that gestational diabetes (GDM) during pregnancy is strongly associated with declines in intellectual function for mothers and a higher risk of developmental, behavioral, and autism spectrum disorders in children.

What makes an admission to a mental health unit a more or less traumatic experience, and what role do nurses play in this experience? A study recently published in the Journal of Clinical Nursing focuses on a question that is as sensitive as it is little explored: the perception of quality of care as a factor that can make a big difference in mental health care.

Patient preference studies (research into what patients value in their treatment) are increasingly used to inform drug development and regulatory approval decisions. But these studies are expensive and time-consuming to conduct. Yet, their results are rarely used beyond their original purpose. Researchers from the University of Twente, in collaboration with international colleagues, identified opportunities to reuse findings from existing studies, thereby improving resource usage during patient-focused drug development.

A new study from Toronto Metropolitan University (TMU) has shown just how important having close siblings and best friends are to social and emotional well-being in early adolescence.

The number of U.S. pediatric radiologists declined from 2016 to 2023, according to a study published online Sept. 9 in the Journal of the American College of Radiology.

Inpatient psychiatric care has dramatically shifted to large for-profit chains, according to new research from Columbia University Mailman School of Public Health and Johns Hopkins Bloomberg School of Public Health. The researchers found that the total number of inpatient psychiatric beds barely changed from 2011 to 2023. But behind the stable headline figure lies a dramatic shift: a decline in beds at general hospitals offset by a rise in beds at standalone psychiatric facilities—particularly those owned by large for-profit chains.

FDA leaders under President Donald Trump are moving to abandon a decades-old policy of asking outside experts to review drug applications, a move critics say would shield the agency's decisions from public scrutiny.

Scientists from the Gray Faculty of Medical & Health Sciences at Tel Aviv University introduced an innovative gene therapy method to treat impairments in hearing and balance caused by inner ear dysfunction. According to the researchers, "This treatment constitutes an improvement over existing strategies, demonstrating enhanced efficiency and holds promise for treating a wide range of mutations that cause hearing loss."

A novel treatment for Leber's Hereditary Optic Neuropathy (LHON), a rare genetic disease that can lead to sudden loss of vision, has been approved for NHS patients following a successful clinical trial co-led by UCL and Moorfields researchers.

A study has tracked the acute muscle-building response in adults engaged in weight-training exercise who were fed either high-fat or lean ground pork burgers with the same amount of protein in each. The findings surprised the scientists, adding to the evidence that muscle-protein synthesis in response to weight training and a post-exercise meal is as complex as the high-protein foods people consume.

People who use e-cigarettes, cigarettes or both face an increased risk for developing diabetes, according to University of Georgia research published in AJPM Focus.

Experiencing intense anxiety, lethargy, irritability, or sadness can be debilitating when trying to accomplish a simple task. For a task as monumental as caring for a baby, these symptoms of perinatal mood and anxiety disorders (PMADs) affect one in five mothers, many who feel unsupported.

A new study from Karolinska Institutet, published in Nature Communications, reveals that cyclin-dependent kinases (CDK) promote DNA replication licensing in human cells by relieving inhibitory signals from RB tumor suppressor proteins. The findings add a new layer to our understanding of how cancer drugs work and may lead to better targeted cancer therapies in the future.

Every spring, Americans dutifully adjust their clocks forward to daylight saving time, and every fall, back to standard time—but no one seems very happy about it. The biannual time shift is not only inconvenient, it's also known to be acutely bad for our health. The collective loss of an hour of sleep on the second Sunday in March has been linked to more heart attacks and fatal traffic accidents in the ensuing days.

Pediatric brain tumors are the deadliest form of childhood cancer, yet most treatments are adapted from adult care and often miss the mark. A new study led by a second-year medical student at Dell Medical School at The University of Texas at Austin outlines why kids' brain tumors are uniquely hard to treat and where the next generation of therapies is heading.