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The patient–doctor relationship is built upon trust in not only doctors' knowledge and skills but also attitudes. Over time, notions of trust in medical education have focused increasingly on trainees becoming "entrustable" to proficiently complete important professional tasks.
In a preclinical study, Cedars-Sinai investigators found that boosting angiotensin-converting enzyme (ACE) in key immune cells called microglia in the brain helped protect the brains of specially bred laboratory mice against Alzheimer's disease. Their findings, published in Nature Aging, could lead to cellular therapies to help treat the disease in humans.
Hours after savoring that perfectly grilled steak on a beautiful summer evening, your body turns traitor, declaring war on the very meal you just enjoyed. You begin to feel excruciating itchiness, pain or even swelling that can escalate to the point of requiring emergency care.
An outbreak of Legionnaires' disease in New York City has killed two people and sickened 58 since late July.
Long overlooked in the field of musculoskeletal study, the tendon is a highly complex anatomical structure that triggers a dynamic but mysterious cellular response when it's injured. In a new study in Nature Communications, University of Rochester researchers for the first time trace and manipulate a key player in the healing process—the epitenon cells that form a thin outer layer surrounding the tendon—and show the remarkable similarity between these cells' activity in mice and humans. Their discovery may pave a path to new translational treatments for a common, highly consequential but poorly understood health issue.
An AI-powered tool from Carnegie Mellon University and collaborators is helping uncover genetic clues to rare diseases, potentially accelerating diagnoses and treatments for conditions that affect only a fraction of the population.
People with the eating disorder ARFID (avoidant/restrictive food intake disorder) severely limit their food intake in terms of quantity or variety—leading to physical and psychological impairments. The condition usually begins in childhood and has so far been studied mainly in children or people who are underweight. Now, researchers at the University of Leipzig Medical Center have shown that adults with a higher body weight can also be affected. The findings have been published in the journal Psychotherapy and Psychosomatics.
Researchers from the University of Birmingham have uncovered a completely new mechanism by which fat cells (adipocytes) control how they store and release fat.
A recent study led by a team of researchers at The Johns Hopkins University School of Medicine examining aging mice has provided what is believed to be the first evidence that amyloid beta protein—small, sticky protein fragment found in people with Alzheimer's disease (AD)—particles build up in the bone marrow of the animals, although not in the exact same form as the large, dense plaques found in the brains of people with Alzheimer's disease.
New fundamental research could help combat treatment-resistant leukemia and prevent relapses in children and adolescents. A group of scientists studied a certain type of leukemia and identified individual stem cell-like cells responsible for relapses in kids. They have also precisely characterized the molecular properties of these cells.
More than 55 million people worldwide live with Alzheimer's and related dementias (ADRD), placing a heavy burden on families and health care. Social isolation is a major—and preventable—risk factor, linked to faster cognitive decline and even early death. ADRD symptoms often worsen isolation, creating a harmful cycle. As isolation grows, especially among older adults, effective social interventions are urgently needed.
The Trump administration aims to bar U.S. veterans from receiving abortions at Department of Veterans Affairs (VA) hospitals in cases of incest, rape or when the pregnancy puts their life at risk.
One in every three people is expected to have cancer in their lifetime, making it a major health concern for mankind. A crucial indicator of the outcome of cancer is its tumor microsatellite status—whether it is stable or unstable. It refers to how stable the DNA is in tumors with respect to the number of mutations within microsatellites.
Researchers from the Germans Trias i Pujol Research Institute (IGTP) have published a study in Scientific Reports that provides an analysis of three-dimensional (3D) culture techniques for generating multicellular tumor spheroids (MCTS) of colorectal cancer. The study, authored entirely by members of the Cancer Genetics and Epigenetics (CGE) group, lists Dr. Sergio Alonso and Dr. Beatriz González as corresponding authors.
As use of the popular anti-diabetic and weight-loss drug Ozempic skyrockets, so have concerns about the medication's side effects. One such side effect is loss of "lean mass"—body weight that isn't fat—raising concerns that Ozempic could be reducing muscle mass and strength.
A new study provides the first visual evidence showing that brain circuits in living animals can be activated by ultrasound waves projected into specific patterns (holograms).
It often starts with restless sleep. Mobility, swallowing, and speaking disorders are also typical. Yet a range of other symptoms make it difficult to diagnose anti-IgLON5 disease. Left untreated, this rare autoimmune disease leads to severe disabilities in just a few years and is often fatal.
You've probably heard that running is tough on your knees—and even that it can cause long-term damage. But is this true?
Every day, we're faced with constant opportunities for stimulation. With 24/7 access to news feeds, emails and social media, many of us find ourselves scrolling endlessly, chasing our next hit of dopamine. But these habits are fueling our stress—and our brains are begging for a break.