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Finding patterns in genetic uncertainty: Clues for inborn errors of immunity

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  • 2025-09-15 21:34 event
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Finding patterns in genetic uncertainty: Clues for inborn errors of immunity
Behind every unexplained medical condition is a patient hoping for clarity and understanding. For people with suspected inborn errors of immunity (IEIs), genetic testing can facilitate individually tailored and effective diagnostics and treatments.

357. There's a new outbreak of Ebola in Africa—here's what you need to know

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The Democratic Republic of the Congo (DRC) has declared a new Ebola outbreak in Kasai Province. It's caused by the most severe strain: Zaire Ebola virus.

358. Better screening tool for sickle cell disease progression

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Near-infrared spectroscopy (NIRS), an optical tool that leverages light-tissue interaction to measure changes in hemoglobin concentration and oxygenation, has been used in a variety of fields due to its ability to measure tissue oxygenation and blood flow noninvasively. In a new study led by Carnegie Mellon University and University of Pittsburgh researchers, NIRS was investigated as a screening tool for adults with sickle cell disease to assess not only oxygenation changes, but also the underlying mechanisms associated with aging with the disease.

359. Over-the-counter sales of overdose reversal drug naloxone decline after initial surge

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Sales of the overdose reversal medication naloxone increased after it was made available to the public without a prescription but then dipped quickly in the period following the debut of over-the-counter sales, according to a new RAND study.

360. New trial aims to advance research into Strep A vaccine development

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A new human challenge trial under way in Melbourne aims to advance research into Strep A, accelerating efforts toward the development of a vaccine.

361. Should you use ChatGPT as a therapist? Tool raises safety concerns among psychology experts

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Sharing how you're feeling can be frightening. Friends and family can judge, and therapists can be expensive and hard to come by, which is why some people are turning to ChatGPT for help with their mental health.

362. Trump's Medicaid cuts were aimed at 'able-bodied adults': Hospitals say kids will be hurt

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Republicans insist that President Donald Trump's cuts to Medicaid were aimed at reducing fraud and getting more of its adult beneficiaries into jobs. But the side effects may include less care for sick kids.

363. Fathers less likely to tackle 'awkward' sex talk

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Mothers are more likely than fathers to discuss sex and relationships with their children, raising concerns that many boys are missing out on gender-specific guidance at a critical time in their lives.

364. Special lactic acids can reduce antibiotic resistance in infants

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Researchers from The Technical University of Denmark, DTU, document that a special subgroup of naturally occurring bifidobacteria plays a crucial role in reducing antibiotic resistance in infants.

365. Stress in the strands: Hair offers clues to children's mental health

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Long-term stress levels, measured through hair samples, may provide important clues about mental health risks in children with chronic physical illness (CPI), according to new research from the University of Waterloo.

366. Finding patterns in genetic uncertainty: Clues for inborn errors of immunity

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Behind every unexplained medical condition is a patient hoping for clarity and understanding. For people with suspected inborn errors of immunity (IEIs), genetic testing can facilitate individually tailored and effective diagnostics and treatments.

367. A call to action ahead of Medicaid work requirements

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With just over a year to go until low-income people covered by Medicaid expansion in 40 states must start verifying they're working, or are exempt from work requirements, a University of Michigan health care researcher says there isn't a moment to waste.

368. 3D bioprinted mini placentas could transform pregnancy research

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By 3D bioprinting miniature placentas, scientists have provided a new way to study complications in pregnancy, with the research led by the University of Technology Sydney (UTS).

369. How HIV enters the genome—study decodes previously unknown mechanism

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Researchers at the German Center for Infection Research (DZIF) at Heidelberg University Hospital have decoded a previously unknown mechanism by which HIV-1 selects its integration targets in the human genome. A research team led by DZIF scientist Dr. Marina Lusic identified RNA:DNA hybrids (R-loops) as molecular signposts for the virus.

370. How to weigh the risks and benefits of kids' play environments

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A new research-backed tool aims to revolutionize how playgrounds and outdoor learning environments are assessed, by recognizing that some risk can be good for a child's development.

371. Should physicians have to see children whose parents oppose vaccinations?

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As Florida seeks to end vaccine mandates, a behind-the-scenes debate in the medical community has been thrust into the public spotlight: Should doctors see young patients whose parents do not want them to get shots?

372. Pre-menopausal women's protein needs after exercise examined

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Women are constantly overwhelmed with diet, health and lifestyle advice, yet are rarely the sole focus of exercise science research.

373. Association between trust of researchers and willingness to participate in Alzheimer's disease biomarker research

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A new study has found that trust in researchers is the strongest factor influencing whether older adults are willing to participate in Alzheimer's disease and related dementia (ADRD) biomarker research. In a survey of 399 older adults with no previous research involvement, those who expressed very high trust were significantly less hesitant to take part in studies, even after accounting for differences in age, education, race and knowledge of ADRD.

374. Large number of low-birth-weight babies born to women living near the Aliso Canyon gas blowout

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Women in their final trimester of pregnancy who lived within 6.2 miles of the Aliso Canyon Natural Gas Storage Field blowout—the largest uncontrolled release of toxic air pollutants from an underground gas storage facility in U.S. history—had a nearly 50% higher-than-expected chance of having a low–birth-weight baby, according to a new study by UCLA researchers.

375. On World Sepsis Day, doctors urge Americans to know the signs

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On World Sepsis Day, health experts remind Americans that sepsis strikes 1.7 million people in the U.S. each year and causes more than 350,000 deaths.

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