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First genetic links between gut fungi, human genetic variation and disease risk discovered

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  • 2025-09-03 01:00 event
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First genetic links between gut fungi, human genetic variation and disease risk discovered
Clinicians' ability to diagnose and treat chronic diseases is limited by scientific uncertainty around factors contributing to disease risk. A study published September 2 in the journal PLOS Biology by Drs. Emily Van Syoc, Emily Davenport, and Seth Bordenstein at Pennsylvania State University, United States, uncovered evidence of the first ternary relationships between human genetic variation, variation in gut mycobiome, and risk of developing chronic disease.

1.143. Shorter, less intense regimen still effective for HPV-linked throat cancer, study shows

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A Mayo Clinic study finds that a shortened, less intense course of radiation and chemotherapy after minimally invasive surgery for HPV-positive oropharyngeal squamous cell carcinoma (HPV+OPSCC) results in less toxicity, substantially lowering the rates of treatment-related side effects while maintaining high cure rates. The findings were published in The Lancet Oncology.

1.144. Genomics study establishes new rare disease diagnosis framework

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A study in China covering 42,703 families affected by rare diseases across 32 provincial regions of China has established a new diagnosis framework for rare diseases. It offers new hope to millions of patients struggling with delayed or incorrect diagnoses.

1.145. Despite relaxed prescribing rules, opioid addiction treatment still hard to find at pharmacies

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Faced with a worsening drug crisis, policymakers in recent years have made it much easier for doctors to prescribe the highly effective opioid addiction treatment buprenorphine. However, many patients may still struggle to find pharmacies carrying the treatment, finds new research led by the USC Schaeffer Center for Health Policy & Economics.

1.146. Dental fear is widespread, but most people want treatment

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Nearly three out of four adults fear going to the dentist, according to a study published in the Journal of the American Dental Association.

1.147. Early Alzheimer's brainwave test detects memory decline years before diagnosis

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A simple brainwave test developed at the University of Bath has been shown to detect signs of memory impairment linked to Alzheimer's disease years before clinical diagnosis is typically possible.

1.148. BlurryScope: A compact, AI-powered microscope for rapid, cost-effective cancer scoring

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A research team at UCLA, led by Professor Aydogan Ozcan, has introduced BlurryScope, a compact, cost-effective scanning microscope that combines simple optical hardware with advanced deep learning algorithms to assess HER2 status in breast cancer tissue samples.

1.149. Adding more green space to a campus is a simple, cheap, healthy way to help stressed, depressed college students

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Stress on college students can be palpable, and it hits them from every direction: academic challenges, social pressures and financial burdens, all intermingled with their first taste of independence. It's part of the reason why anxiety and depression are common among the 19 million students now enrolled in U.S. colleges and universities, and why incidents of suicide and suicidal ideation are rising.

1.150. Widely available nasal spray reduces risk of coronavirus infection by two-thirds, clinical study suggests

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A research team at Saarland University has demonstrated in a clinical study that a widely used anti-allergy nasal spray containing the active ingredient azelastine can significantly reduce the risk of infection with the SARS-CoV-2 virus. The results of the placebo-controlled trial involving 450 healthy participants have now been published in JAMA Internal Medicine.

1.151. Fluorine 'forever chemical' in medicines not leading to added drug reactions

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Medicines containing a type of PFAS or "forever chemical" called fluorine are not leading to higher numbers of adverse drug reactions, according to new data analysis.

1.152. First genetic links between gut fungi, human genetic variation and disease risk discovered

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Clinicians' ability to diagnose and treat chronic diseases is limited by scientific uncertainty around factors contributing to disease risk. A study published September 2 in the journal PLOS Biology by Drs. Emily Van Syoc, Emily Davenport, and Seth Bordenstein at Pennsylvania State University, United States, uncovered evidence of the first ternary relationships between human genetic variation, variation in gut mycobiome, and risk of developing chronic disease.

1.153. Study finds ethnicity is key in hypertension treatment

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New groundbreaking results from a clinical trial reinforce the critical importance of personalized medicine in hypertension care.

1.154. Research reveals protein ADAR1 as new therapeutic target to treat brain cancer

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Research has revealed a new mechanism within cancer cells that could be exploited to treat glioblastoma—one of the deadliest types of brain tumors.

1.155. Medical debt in collections persists after cancer diagnosis

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Modest amounts of medical debt in collections persist for years after cancer diagnosis, according to a study published online Aug. 28 in JAMA Oncology.

1.156. Older adults share experiences of aging positively

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A new study has revealed the most important factors for aging positively, according to the lived experiences and views of older adults in England.

1.157. Neurosurgeon describes 8 common myths about back pain

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Back pain is common, but several myths about it persist. Meghan Murphy, M.D., a neurosurgeon at the Mayo Clinic Health System in Mankato, describes eight of them and provides the facts.

1.158. Turning off TV could be ticket to better mental health in middle age

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Replacing time spent watching TV with other activities can help prevent depressive disorder in middle-aged adults, revealed a new study in European Psychiatry, published on behalf of the European Psychiatric Association by Cambridge University Press. The effects were less pronounced in older and younger adults.

1.159. Peripheral Artery Disease Awareness Month urges screening and advocacy in national effort to prevent amputations

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September is Peripheral Artery Disease (PAD) Awareness Month, a time to take action against a disease that affects more than 10 million Americans and is the largest cause of nontraumatic amputations in the United States. That's why the PAD Pulse Alliance, a coalition of leading medical societies dedicated to improving vascular health, is urging patients, providers, and policymakers to act through its Get a Pulse on PAD Campaign.

1.160. Amid cuts, SNAP-Ed study reveals partnerships support healthy communities

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A critical program supporting healthy communities in Illinois and across the country took a devastating hit on July 4 when HR1, the federal budget reconciliation bill, was passed and signed into law. In addition to slashing funding for the Supplemental Nutrition Assistance Program (formerly known as food stamps), the bill eliminated funding altogether for SNAP's companion program, SNAP-Education, which works with community partners to educate SNAP-eligible families and individuals on obesity prevention, healthy foods, active lifestyles, and stretching food dollars.

1.161. Brain cancer cells can be 'reprogrammed' to stop them from spreading

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Scientists have found a way to stop brain cancer cells spreading by essentially 'freezing' a key molecule in the brain.

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