Frailty fuels gut imbalance and can drive post-surgery gastrointestinal risk

Researchers at Moffitt Cancer Center have created the first genetically engineered model of lung cancer in naked mole rats, a species long thought to be resistant to cancer. The findings, published in Cancer Discovery, shed light on how cancer begins in this unusual rodent and may reveal new parallels to tumor development in humans.

A research team has developed an implantable wireless neural interface capable of delivering drugs precisely to deep regions of the brain.

Influenza (flu) can be fatal, but just how it causes severe damage to the lungs has been a mystery—until now.

Researchers have harnessed the power of artificial intelligence to tackle one of the most complex challenges in immunology: predicting how T cells recognize and respond to specific peptide antigens. Using AlphaFold 3 (AF3), an AI/ML model, designed for protein structure prediction, the team demonstrated a novel approach to model T cell receptor–peptide/major histocompatibility complex (TCR-pMHC) interactions with growing accuracy. The paper is published in the journal Frontiers in Immunology.

Scientists have discovered why older people are more likely to suffer severely from the flu, and can now use their findings to address this risk.

Run. Red. World. Pronouncing the "r" sound in these words requires precise control of the tongue. For most children, this happens naturally, but many children struggle with residual speech sound disorder (RSSD) in which speech errors persist past the age of eight.

Only one in seven online stock photo images of blood pressure monitoring correctly show how blood pressure should be measured, contributing to potentially inaccurate readings at home and in physicians' offices, health care facilities or hospitals, according to new research published in Hypertension.

A new hydrogel applied directly to vaginal tissues may help alleviate the negative impacts of menopause, according to a new study from scientists at the University of California San Diego. The results, published in Advanced Materials, could pave the way for a hormone-free treatment that alleviates vaginal dryness and pain caused by genitourinary syndrome of menopause (GSM), which negatively impacts quality of life for millions of women.

Women's fertility is influenced not only by the quality of their eggs but also by the interactions between somatic cells in the ovary. A recent study by TalTech researchers, conducted in international collaboration, provides a better understanding of how different ovarian cells exchange information. This knowledge is crucial for advancing fertility treatments.

Scientists in the laboratory of Weiguo Cui, Ph.D., professor of Pathology in the Division of Experimental Pathology, have identified novel molecular mechanisms that help specialized T-cells maintain long-term immunity in response to chronic infection and cancer, according to recent findings published in Nature Immunology.

Asthma is one of the most common chronic diseases in children worldwide. But not all children are equally likely to develop this disease. Children from homes with fewer resources have a significantly higher risk of developing asthma than children from better socioeconomic conditions. This is the finding of a new study that, for the first time, has examined the drivers of these inequalities across six European high-income countries.

Researchers at the University of Bath have discovered how DNA damage caused by a faulty DNA protection and repair system can lead to neurodegenerative disorders such as motor neuron disease (MND).

With the prevalence of autism increasing in recent years, more autistic people are attending college and university. (There are different ways to identify in the autistic community, with some people preferring to call themselves "autistic" rather than "a person with autism;" we're taking the former approach).

Virtual reality is emerging as a powerful tool to improve care for veterans, including helping community members recognize suicide warning signs. Researchers at The University of Texas at Arlington have conducted two studies exploring how the technology can address the complex challenges veterans face.

Say you win a radio sweepstakes giving you two tickets to a sold-out concert the upcoming weekend. You eagerly text your friend and ask if they'd like to join.

University of Florence–led investigators report that estrogen-regulated renal progenitor cells shape pregnancy adaptation in mice with failure of estrogen receptor alpha signaling precipitating preeclampsia, maternal kidney injury, and offspring vulnerability to hypertension and chronic kidney disease.

Just as a computer's operating system can be rewritten after a major update, dengue infection can "re-program" the body's immune system, leaving a long-lasting genetic imprint that influences how people respond to future infections—an effect not seen with vaccination.

Suicide is a leading cause of death in postpartum women—and it is a preventable one. It is estimated that nearly half of mothers experiencing perinatal depression are undiagnosed and are not receiving treatment. But when women are given vital mental health tools in an accessible manner, their deaths can be prevented.