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From injury to agony: Scientists discover brain pathway that turns pain into suffering

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  • 2025-07-10 02:17 event
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From injury to agony: Scientists discover brain pathway that turns pain into suffering
Pain isn't just a physical sensation—it also carries emotional weight. That distress, anguish, and anxiety can turn a fleeting injury into long-term suffering.

250. AI and open-source software promise faster, easier biomedical imaging

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Two new open-source tools are set to make fluorescence lifetime imaging microscopy—or FLIM—faster, simpler and more accessible. Developed by Ph.D. student Sofia Kapsiani in Professor Gabi Kaminski Schierle's Molecular Neuroscience Group, the tools tackle long-standing technical and practical barriers in biomedical imaging.

251. Verbal response time reveals hidden sleepiness in older adults

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A new study led by UCLA investigators shows that Verbal Reaction Time (VRT), the amount of time it takes a person to respond verbally, can be a marker of sleepiness in older adults. The study, which measured participants' voice data through standardized cognitive assessments, shows how VRT can passively detect excessive sleepiness, especially among older individuals using sedative medications.

252. Study shows sexual pleasure remains important for women across menopause transition

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Although there is a lot of discussion around negative aspects of aging and sexual problems, a new nationally representative study of 1,500 U.S. women aged 40–65 reveals that despite reporting masturbating less often, most postmenopausal women continue to experience orgasm at the same frequency and quality as their younger peers.

253. Lemurs show no age-related inflammation, challenging assumptions about human aging

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What can lemurs tell us about inflammation and aging, aka "inflammaging" in humans? That's the question Elaine Guevara, a biological anthropologist who studies the evolution of life history and aging in primates, set out to understand.

254. Bats replay flight memories in fixed time packets, providing new clues into how memories are stored

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Every day, our brain takes countless fleeting experiences—from walks on the beach to presentations at work—and transforms them into long-term memories. How exactly this works remains a mystery, but neuroscientists believe that it involves a phenomenon called neural replay, in which neurons rapidly recreate the same activation sequences that occurred during the original experience. Surprisingly, neural replays can happen both before and after an experience, suggesting they help in both memory storage and also future planning.

255. Green spaces boost children's cognitive skills and strengthen family well-being

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Access to nature promotes physical and mental health, and it is vital for children's social and emotional development. Outdoor activities also influence family dynamics, helping to reduce stress and encourage connections.

256. Breathing dirty air may raise the risk of a common brain tumor

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People exposed to higher levels of air pollution may be more likely to develop meningioma, a typically noncancerous brain tumor, according to a large study published in Neurology. This common type of brain tumor forms in the lining of the brain and spinal cord. The findings do not prove that air pollution causes meningioma; they only show a link between the two.

257. Chromosomal abnormality scores unlock path to personalized immunotherapy

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In a newly published article in Nature Genetics, researchers from the University of Chicago have identified tumor aneuploidy—an imbalance in the number of chromosomes—as a powerful biomarker associated with resistance to immunotherapy across cancer types. The study emphasizes how combining immunotherapy with radiation may help overcome the issue of therapy resistance, offering a new framework for predicting treatment response and personalizing cancer therapy.

258. How active video games could benefit children with obesity

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New research shows that contrary to the fears of many parents, video games might be able to help children with obesity exercise more.

259. From injury to agony: Scientists discover brain pathway that turns pain into suffering

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Pain isn't just a physical sensation—it also carries emotional weight. That distress, anguish, and anxiety can turn a fleeting injury into long-term suffering.

260. New method traces cancer cell evolution from a single tissue sample

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Cancer does not develop overnight. It can take decades for cancer‐promoting changes in the genome to eventually lead to the formation of a malignant tumor.

261. Scientists reveal how Epstein-Barr virus protein EBNA-LP rewires DNA to drive cancer

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Scientists at The Wistar Institute have discovered how a key protein from the Epstein-Barr virus (EBV), EBNA-LP, fundamentally rewires the three-dimensional structure of DNA in infected B cells to promote cancer development.

262. A new drug could soon help treat cancer and viral infections

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An international team of researchers led by Konstanz biologists has identified a molecular mechanism that regulates the activity of N-myristoyltransferases. This enzyme plays a role in biological signaling pathways, where dysregulation can lead to serious illness.

263. New compound shows promise in preventing premature births in mice

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After nearly 15 years' research, scientists at the UdeM-affiliated CHU Sainte-Justine have developed a compound that has shown remarkable potential in preventing prematurity in mice.

264. 2017 to 2024 saw more seniors with prolonged ED length of stay

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The proportion of older adults with prolonged emergency department length of stay (LOS) and boarding times increased from 2017 to 2024, according to a research letter published online June 30 in JAMA Internal Medicine.

265. Cashew identified as increasingly relevant allergen triggering anaphylaxis in children

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Cashew is an increasingly relevant allergen leading to anaphylaxis in children, according to a study published online June 13 in Allergy.

266. 'It just makes you feel less alone': Using the power of play to break menopause taboos in the workplace

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Health psychologists from the University of Staffordshire have adopted a novel approach to support women going through the menopause.

267. Substances isolated from marine sponges show potential for treating malaria

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Brazilian researchers have discovered chemical compounds in marine sponges that have the potential to eliminate the malaria parasite, including strains that are resistant to conventional antimalarial drugs. The research results were published in the journal ACS Infectious Diseases.

268. Novel AI method sheds light on how enzyme linked to Alzheimer's selects its targets

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Researchers from DZNE, Ludwig-Maximilians-Universität München (LMU), and Technical University of Munich (TUM) have found that the enzyme "gamma-secretase"—implicated in Alzheimer's disease and cancer—selects its reaction partners according to a complex scheme of molecular features.

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