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From counting sheep to white noise and weighted blankets, people have tried innumerable ways to get a good night's sleep. Sleep disruptions can have far-reaching negative consequences, impacting cardiovascular and metabolic health, memory, learning, productivity, mood regulation, interpersonal relationships and more.
Erythritol may impair cellular functions essential to maintaining brain blood vessel health, according to researchers at the University of Colorado Boulder. Findings suggest that erythritol increases oxidative stress, disrupts nitric oxide signaling, raises vasoconstrictive peptide production, and diminishes clot-dissolving capacity in human brain microvascular endothelial cells.
Shortly after she was born, Laura Valentine turned blue.
Fetuses more exposed to certain air pollutants show changes in the size of specific brain structures, particularly during the second and third trimesters of pregnancy. This is the main finding of a new study led by the Barcelona Institute for Global Health (ISGlobal), in collaboration with the BCNatal center (Hospital Sant Joan de Déu, Hospital Clínic, and University of Barcelona) and the Hospital de la Santa Creu i Sant Pau.
Germany's BioNTech is buying domestic rival CureVac for $1.25 billion, the companies said Thursday, bringing together two pharmaceutical firms specialized in mRNA technology with the goal of advancing cancer treatments.
A new molecule developed by University at Buffalo researchers acts like a local, long-lasting anesthetic, providing robust pain relief for up to three weeks, according to the results of preclinical studies reported recently in the journal Pain.
Out-of-body experiences—where people feel like spirits disconnected from their physical form—may be a coping mechanism triggered by trauma or other overwhelming stress, new University of Virginia School of Medicine research suggests.
A study published in the journal Scientific Reports indicates that physical exercise combined with omega-3 supplementation considerably improves the immune response and reduces the severity of chronic apical periodontitis.
Inspired by advances in cancer therapy, a team at the Buck Institute has engineered immune cells equipped with specialized targeting devices called chimeric antigen receptors (CARs) that can distinguish and respond to tau tangles and various forms of toxic amyloid plaques, both of which are implicated in Alzheimer's disease pathology.
Colorectal cancer is one of the most common types of tumor and is responsible for around 10% of cancer-related deaths worldwide. The tumor is particularly dangerous when it forms metastases—i.e. secondary tumors—in other organs. This occurs primarily in the liver and lungs, and more rarely in the brain.
A growing number of firearm suicides in the United States occur outside the home, most commonly in motor vehicles, according to a study published online in JAMA Network Open.
The U.S. Food and Drug Administration has approved George Medicines' Widaplik (telmisartan, amlodipine, and indapamide) for the treatment of hypertension in adults.
Hyponatremia, or low blood sodium concentration, is typically viewed as a symptomless condition—until recently. A research team has demonstrated that chronic hyponatremia (CHN) can directly cause anxiety-like behaviors in mice by disrupting key neurotransmitters in the brain.
Thanks to lab-grown miniature intestines, researchers at Uppsala University have successfully mapped how aggressive Shigella bacteria infect the human gut. The study opens the door to using cultured human mini-organs to investigate a wide range of other serious infections.
A rich and varied mix of microbes in the mouth, particularly bacteria, is not only important for our oral health, but may hold clues for other conditions.
Researchers, led by UC San Francisco, tested the effectiveness of a weeklong, web-based well-being intervention, known as the Big Joy Project. This consisted of daily micro-acts, which included asking someone to share a fun, inspiring, or proud moment, making a gratitude list, and performing a kind act to brighten someone's day.
The human brain, like the brain of other mammals, is known to start developing before birth, via a coordinated sequence of molecular and cellular processes. Neuroscience studies have found that the choroid plexus (ChP), a specialized brain structure that regulates the production of a liquid that nourishes the brain and spinal cord, plays a key role in the brain's early development.
Leg amputation rates caused by arterial disease are four times as high in the most disadvantaged areas in England. The study, from the University of Sheffield, also found patients living in the most socioeconomically disadvantaged areas are more likely to die following leg amputation compared with those living in the least disadvantaged areas.
Researchers at the Indiana University School of Medicine have developed a more accurate and cost-effective method to predict asthma diagnoses in children by using readily available electronic health records. This scalable approach could enhance early detection rates and help reduce the risk of asthma disease progression in young patients.