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'Google for DNA' enables rapid full-text searches of vast genetic archives

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  • 2025-10-09 20:24 event
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'Google for DNA' enables rapid full-text searches of vast genetic archives
Rare hereditary diseases can be identified in patients and specific mutations in tumor cells detected—DNA sequencing revolutionized biomedical research decades ago. In recent years, new sequencing methods (next-generation sequencing) in particular have resulted in numerous scientific breakthroughs. In 2020/2021, for example, they enabled the rapid decoding and global monitoring of the SARS-CoV-2 genome.

46. Postmortem brain study finds way to correct for decay effects when looking for schizophrenia footprint

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Skoltech researchers have investigated the way the composition of small molecules called lipids and metabolites varies in the brain in the first hours and days after death.

47. Study suggests air pollution can contribute to obesity and diabetes

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Long-term exposure to fine air pollution can impair metabolic health by disrupting the normal function of brown fat in mice. A study co-led by the University of Zurich shows that this occurs through complex changes in gene regulation driven by epigenetic mechanisms. The results demonstrate how environmental pollutants contribute to the development of insulin resistance and metabolic diseases.

48. Restless leg syndrome's connection to Parkinson's disease

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Three research hospitals in the Republic of Korea are reporting that restless leg syndrome was associated with an increased risk of Parkinson's disease, with 1.6% of patients with restless leg syndrome developing Parkinson's disease vs. 1.0% in matched controls and a shorter average time to diagnosis at a 15-year horizon.

49. How employers can promote physical activity among workers: Three messages based on research

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We all know about the benefits of physical activity—not just to reduce the risks of chronic disease and physical injuries but also to improve mental health and productivity at work. But many people just don't get as much physical activity as they should.

50. Why do some songs get stuck in our heads so easily? The science of earworms

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If you've watched the movie KPop Demon Hunters and see the word "golden," what happens?

51. High schoolers face growing risk of firearm-related violence, study shows

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Firearm-related deaths are rising dramatically among high school youth, according to a new study led by Washington State University researchers.

52. Scientists fix genetic defect in mice tied to brain disorders that include autism and epilepsy

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In an exciting scientific first, researchers at the Allen Institute successfully designed a new gene therapy that reversed symptoms related to SYNGAP1-related disorders (SRD) in mice. These are a class of brain disorders that can lead to severe and debilitating symptoms including intellectual disability, epilepsy, motor problems, and risk-taking behaviors in humans. In most cases, SRDs are caused when someone has only one working copy of the SYNGAP1 gene instead of the normal two.

53. Certain dietary fatty acids can supercharge cancer-fighting immune cells

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A research team at the LKS Faculty of Medicine of the University of Hong Kong (HKUMed) has discovered that certain dietary fatty acids can supercharge the human immune system's ability to fight cancer. The team found that a healthy fatty acid found in olive oil and nuts, called oleic acid (OA), enhances the power of immune γδ-T cells, specialized cells known for their cancer-fighting properties.

54. Diabetic teens with high blood sugar found to have higher neuropathy risk in adulthood

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Poor blood sugar control in adolescence increases the risk of painful future complications for people with type 1 diabetes, research co-led by University of Michigan suggests.

55. 'Google for DNA' enables rapid full-text searches of vast genetic archives

  • 6 hours ago schedule
  • medicalxpress.com language

Rare hereditary diseases can be identified in patients and specific mutations in tumor cells detected—DNA sequencing revolutionized biomedical research decades ago. In recent years, new sequencing methods (next-generation sequencing) in particular have resulted in numerous scientific breakthroughs. In 2020/2021, for example, they enabled the rapid decoding and global monitoring of the SARS-CoV-2 genome.

56. Study finds tailored exercise program feasible for adults over 80 with osteoarthritis

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A new NDORMS study has found that a tailored exercise program for people aged 80 years and older with hip and/or knee osteoarthritis and other long term health conditions is both practical and acceptable, paving the way for a large clinical trial.

57. GLP-1s show promise in treating alcohol and drug addiction

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A popular class of therapies for treating diabetes and obesity may also have the potential to treat alcohol and drug addiction, according to a new paper published in the Journal of the Endocrine Society.

58. Study confirms it's 'never too late' to see survival benefits from quitting smoking—even with late-stage cancer

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New research published online in the Journal of the National Comprehensive Cancer Network finds that people with cancer who quit smoking had a much lower risk of dying within two years compared to those who kept smoking. The paper is titled "Smoking Cessation and Mortality Risk in Cancer Survivorship: Real-World Data From a National Cancer Institute–Designated Cancer Center."

59. Short inspirational videos as effective as meditation at reducing stress, study suggests

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Watching short inspirational videos may be just as effective at reducing stress as meditation, according to research published by the American Psychological Association.

60. Pain during opioid addiction treatment tied to worse outcomes

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Though rarely considered during treatment for opioid use disorder, uncontrolled pain is strongly linked to less success in treatment outcomes, a lower quality of life, and mental health issues, a new study led by a Virginia Tech addiction researcher found.

61. Do the new obesity drugs pay for themselves?

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Drugs like Ozempic have been found to be effective at promoting weight loss. They are also remarkably expensive. Some argue that the medications could ultimately save health care systems money by reducing the risk of obesity-associated diseases.

62. Obesity drugs improve health but may not reduce overall health care costs

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Drugs like Ozempic have been found to be effective at promoting weight loss. They are also remarkably expensive. Some argue that the medications could ultimately save health care systems money by reducing the risk of obesity-associated diseases.

63. Study calls for universal vaccination for pregnant women, children against RSV

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A team of researchers led by a University of Florida Health scientist recommends the universal immunization of pregnant women and infants against RSV, following a years-long assessment of the impact of hospitalizing children with respiratory syncytial virus.

64. Time for the gloves to come off

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The indiscriminate use of non-sterile gloves in hospitals and clinics is significantly adding to environmental pollution, with little evidence to prove that there are substantial benefits.

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