HER3-targeted antibody-drug conjugate shows promise for treatment-resistant solid tumors

Having a job may give people a better chance at recovery following treatment for alcohol use disorder. Nationwide data from people who received outpatient treatment for alcohol use disorder found that people with full-time jobs drank less frequently at the end of treatment. And those whose employment status increased during treatment, for example from unemployed to employed full-time, had greater reductions in alcohol use frequency than those whose employment status did not change.

Alcohol-related genetic variants influence the effects of a medication for treating alcohol use disorder (AUD), according to an innovative study. The findings point to opportunities for new research approaches and customized treatments for patients.

A proposed classification system appears highly accurate in evaluating nasal deformities in infants with cleft lip and/or palate (CLP), reports a study in the May/June issue of The Journal of Craniofacial Surgery.

Over 10 million infants under six months old may currently be underweight, according to a new analysis of data collected across low- and middle-income countries (LMICs).

Scientists at the Liverpool School of Tropical Medicine (LSTM) have developed a more precise diagnostic tool to distinguish between two closely related threadworm species, improving the global surveillance of the disease strongyloidiasis.

West Virginia University research has revealed negative intergenerational reproductive health effects from the Japanese American detainment camps of World War II.

Fluoride has been added to public water systems in the United States since 1945 to strengthen tooth enamel and fight off bacteria, ultimately reducing tooth decay. Mass General Brigham researchers developed a model to estimate dental health outcomes for children if the United States were to ban fluoridation of public water. The new study, published in JAMA Health Forum, found that banning fluoride would substantially increase dental decay and costs particularly for publicly insured and uninsured children.

Federal health officials have pulled back a key recommendation that pregnant women get the COVID-19 vaccine—causing sharp criticism from doctors and other experts.

Researchers at the Ragon Institute have made a significant discovery about how antibodies can directly enhance the body's ability to fight Mycobacterium tuberculosis (Mtb), the bacteria responsible for tuberculosis (TB). Despite decades of research, TB remains one of the deadliest infectious diseases worldwide, with about 10 million new cases and 1.6 million deaths annually. Currently, there is no highly effective vaccine, highlighting the urgent need for new insights and treatments.

A pilot study from Michigan Medicine researchers found that the Mediterranean diet may provide symptom relief for people with irritable bowel syndrome (IBS). The work is published in the journal Neurogastroenterology & Motility.

Scientists at the University Medical Center Hamburg-Eppendorf (UKE) and Heidelberg University Hospital (UKHD) have investigated potential risk factors for multiple sclerosis (MS) in childhood and adolescence as part of the German National Cohort (NAKO).

Hormel Foods is recalling more than 256,000 pounds of its Dinty Moore Beef Stew amid reports that wood fragments were found in some cans, according to U.S. health officials.

A new study by investigators from Mass General Brigham showed that a new app they created can help improve the quality of life for caregivers of patients undergoing bone marrow transplant (BMT). The researchers conducted a randomized clinical trial and found that caregivers assigned to use the app showed significantly greater improvements in quality of life, burden, and mood symptoms compared to those who did not have the app. They detailed their findings in a presentation at the American Society of Clinical Oncology annual meeting and a paper simultaneously published in the Journal of Clinical Oncology.

Anticipating the conception of a child can be accompanied by a lot of uncertainty about how to plan for pregnancy and parenthood. But relatively few people are aware that the things they do months or years before conceiving can influence the development of their future children.

Prevailing theories about why young people experience psychotic breaks at a young age rely on individual factors like exposure to child abuse, school bullying, or drugs.

In 2024, Brazil celebrated the 20th anniversary of the Bolsa Família Program (BFP), one of the world's largest conditional cash transfer initiatives. A new study published in The Lancet Public Health shows that the BFP has prevented more than 8.2 million hospitalizations and 713,083 deaths in Brazil between 2004 and 2019. In addition, it is estimated that an additional 683,721 deaths could be prevented if the program's coverage is expanded by 2030.

America's primary care doctors are burning out, cutting back their hours, and leaving their practices early, driven in part by the demands of handling the flood of digital messages from their patients.

The New South Wales government this week announced reforms that will allow some general practitioners (GPs) to treat and potentially diagnose attention-deficit hyperactivity disorder (ADHD).