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HIV and Alzheimer's pathways collide: Protein fragment disrupts virus assembly in brain cells

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  • 2025-09-04 00:02 event
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HIV and Alzheimer's pathways collide: Protein fragment disrupts virus assembly in brain cells
A new Northwestern Medicine study has uncovered a surprising molecular link between HIV-1 and a protein fragment associated with Alzheimer's disease, according to findings published in the Proceedings of the National Academy of Sciences.

1.046. Sip smarter: Apple juice effects on oral health are short-lived, but there are caveats

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A new study led by the University of Portsmouth suggests our saliva is stronger than we thought. The research, published in PLOS One, is the first to examine how drinking apple juice affects saliva's lubricating properties using advanced scientific techniques.

1.047. Virtual reality test reveals impaired spatial orientation skills tied to dementia risk

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Individuals with an increased risk of dementia due to Alzheimer's disease may have impaired spatial orientation skills. DZNE researchers have come to this conclusion based on a study involving around 100 older adults who were tasked with determining their position within a virtual environment.

1.048. Rising CVD costs drives investigation of cardiovascular health in young adults

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Cardiovascular disease (CVD) remains the leading cause of death and disability for adults in the U.S. Recent projections from the American Heart Association suggest that by 2050, more than 45 million American adults will have clinical CVD and more than 184 million will have hypertension.

1.049. Key genetic characteristics of compatibility when transplanting blood cell-producing stem cells identified

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Transplanting hematopoietic stem cells from healthy individuals is one of the possible treatments for blood cancers. In Switzerland, it involves nearly 300 patients per year. However, nearly half of transplants fail, mainly due to complications related to imperfect genetic compatibility between the donor and recipient.

1.050. Prefrontal cortex can be safely biopsied during deep brain stimulation

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Obtaining a prefrontal cortex (PFC) biopsy during deep brain stimulation (DBS) procedures is safe, according to a study published online Sept. 3 in Neurosurgery.

1.051. Ethiopia's emergency medical response system is up and running. what other countries can learn from it

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Ethiopia has built a national emergency medical team and hosts Africa's first World Health Organization (WHO)-certified regional training hub. It offers a robust, African-led model for strengthening health emergency response systems across the continent.

1.052. Chronic benzodiazepine consumption impacts sleep quality in older adults, new research shows

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Long-term use of benzodiazepine and related drugs has been linked to poorer quality sleep in older adults with insomnia. While they are cheap, commonly prescribed and widely available in Quebec, these drugs are also addictive: quitting cold turkey can lead to serious withdrawal symptoms, including increased risk of falls, hospitalization and cognitive issues.

1.053. US West Coast states announce new agency for vaccine guidelines

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California, Washington and Oregon announced Wednesday they will form a new public health body to issue vaccine guidelines, saying the move is needed to counter the Trump administration's growing "politicization" of science.

1.054. Yes, weighted vests can help amp up your workout. Here's what to know

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In the fitness class Jessie Syfko created for a nationwide gym chain, exercisers wear weighted vests that add a challenge to their workouts.

1.055. HIV and Alzheimer's pathways collide: Protein fragment disrupts virus assembly in brain cells

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A new Northwestern Medicine study has uncovered a surprising molecular link between HIV-1 and a protein fragment associated with Alzheimer's disease, according to findings published in the Proceedings of the National Academy of Sciences.

1.056. Can meat really protect against cancer-related deaths, as a new study indicates?

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For years, health authorities have warned against red meat consumption, with the World Health Organization's cancer research arm classifying it as "probably carcinogenic to humans." But a controversial new study challenges that position, suggesting that animal protein might protect against cancer deaths rather than cause them.

1.057. Lack of childhood friendships linked to suicidal thoughts in those over 50

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An international University of Helsinki study has found that adverse childhood circumstances increase the risk of suicidal ideation in later life.

1.058. Biological link between two common neurological conditions that could save the NHS millions in treatment costs

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A systematic review of research spanning 34 years has found a biological link between two common neurological conditions that can potentially save the NHS millions by streamlining treatments that currently cost the NHS about £2 billion a year.

1.059. Do weighted blankets work for anxiety? Here's what the evidence shows

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They have been promoted as a remedy for anxiety and sleeplessness, with celebrities and influencers swearing by their calming effects. Weighted blankets—heavy throws filled with glass beads or plastic pellets—have gone from a niche therapeutic tool to a mainstream wellness must-have, promising better sleep and reduced stress for anyone struggling to unwind.

1.060. Genetic tests for cancer can give uncertain results: New science is making the picture clearer to guide treatment

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Cancer treatment is becoming more personalized. By considering a patient's unique genetic and molecular profile, along with their lifestyle and environmental factors, doctors can make more accurate treatment decisions. This approach, known as personalized or precision medicine, has been increasingly used in South Africa and has expanded to other African countries in recent decades. It requires doctors to rely more on genetic tests to guide decisions. But these tests don't always give clear answers. Functional genomics may offer a way to improve the interpretation of unclear genetic test results. We spoke to physiological scientist Claudia Christowitz about it.

1.061. Young people want adults to be involved in their digital lives

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Young people have a nuanced view of how their digital lives affect their mental health and want more support and involvement from the adults around them. This is shown in an international study published in The Journal of Adolescent Health by researchers at Karolinska Institutet in collaboration with UNICEF.

1.062. Rare immune cells offer new hope for treating acute respiratory distress syndrome

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Basophils, a type of white blood cell, promote recovery from acute respiratory distress syndrome (ARDS) in mice, according to researchers at Science Tokyo. In a mouse model of ARDS, basophils were found to release interleukin-4 (IL-4), which suppresses inflammatory neutrophils in the lungs during the recovery stage. The study suggests that targeting the basophil–IL-4–neutrophil pathway could offer a new therapeutic approach for ARDS, a condition with high mortality rates and no dedicated treatments.

1.063. Quitting time: Neurons that drive sociable behavior in children and teens turn off in adulthood

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Pediatricians and parents—and, really, anyone who works with children—have long known that a child's social needs evolve with age. Yale researchers have now discovered the neurological signaling that marks this process.

1.064. Brain-liver circuit links stress to increased blood sugar and type 2 diabetes risk

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A study discovered a circuit in the brain that connects stress with increased glucose and therefore may link stress to type 2 diabetes. In stressful situations, this circuit from the amygdala to the liver naturally provides a burst of energy. When introducing chronic stress and a fatty diet, researchers observed a disruption in the circuit's output, specifically, an excess of glucose production in the liver. Long-term elevations in glucose can cause hyperglycemia and increase the risk of developing type 2 diabetes.

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