How PFAS disrupt healthy function in human liver cells

Scientists at Scripps Research have developed a novel method that uses artificial intelligence (AI) and advanced imaging techniques to more accurately and efficiently identify therapeutic antibodies to treat infectious diseases.

Tumors are stressful places for cancer-fighting immune cells. Low oxygen, high acid levels, and other stressors put strain on mitochondria, the cell's energy factories, leading to T cell exhaustion and poor cancer outcomes.

Green tea is an ancient beverage recognized for its medicinal and antioxidant properties. It has been widely studied for its beneficial effects on metabolic diseases, such as obesity and type 2 diabetes. Recent studies have deepened our understanding of the mechanisms of action of this infusion and revealed that green tea treatment reduced weight and significantly improved glucose sensitivity and insulin resistance in obese mice. These results reinforce the potential relevance of the beverage as an adjunct in the treatment of obesity in humans.

A study conducted by the University of Eastern Finland and Fimea found that the Finnish news media has given GLP-1 agonists used to treat obesity, such as semaglutide, a great deal of attention while many other new medicines have been ignored. Based on preliminary results, media visibility is not evenly divided between medicines intended for different indications, and the amount of visibility does not always correspond to such things as the user-specific costs of medicines or the prevalence of indications.

People with chronic insomnia may experience faster declines in memory and thinking skills as they age—along with brain changes that can be seen on imaging scans—than people who do not have chronic insomnia, according to a study published in Neurology.

Surgical patients in rural areas who are undergoing colectomy for cancer could benefit greatly from the expanded use of minimally invasive surgery, according to new research findings published in the Journal of the American College of Surgeons.

The hospital industry is one of the most important sectors of the U.S. economy because of its size and its impact on the health and well-being of the population. While much research has documented the effects of mergers on cost and quality, we know less about the effects of such actions on access to care.

Home care for older adults has received considerable attention in the Finnish media in recent years. A recent study conducted at the University of Eastern Finland found that newspaper images of home care tend to paint a picture of efficient care workers in a hectic work environment, while portraying older clients as passive recipients of care.

New research has revealed that people with similar levels of autistic traits are more attracted to each other, and their brains synchronize in unique ways during passive and active communication.

Children with a rare, debilitating muscle disease could benefit from the findings of new research by experts at UCL and Great Ormond Street Hospital (GOSH).

New research from the University of Minnesota Medical School is providing important insights into how COVID-19 persists in cancer patients even long after testing positive. The findings were recently published in iScience.

An international multidisciplinary team has demonstrated for the first time that CRISPR-based gene activation (CRISPRa) can be used to treat genetic heart disease in vivo. The study, published in the European Heart Journal and presented at the European Society of Cardiology Congress in Madrid, paves the way for novel targeted therapies for patients with genetic cardiac disorders. This approach could be especially useful for patients with conditions caused by mutations in genes too large to be targeted with conventional gene therapy.

An international team led by the Clínic-IDIBAPS-UB along with the Institute of Cancer Research, London, has developed a new method based on DNA methylation to decipher the origin and evolution of cancer, which makes it possible to predict its future clinical course. The study, published today in the journal Nature, analyzes the evolution of the tumors of 2,000 patients with leukemias and lymphomas.

Interorganizational collaborations are increasingly used to tackle some of society's most complex challenges. In health care, this takes many forms, such as strategic alliances, interorganizational networks, joint ventures, and public-private partnerships. The effectiveness of these collaborations hinges on participants pooling expertise toward the joint goal, but also on whether participants leverage each other's expertise for their own organizations' independent goals. The spillover of progress on those independent goals can sustain participation in the collaboration itself.

UK researchers on Wednesday announced the trial of a blood test for Alzheimer's which it is hoped will transform diagnosis of the disease.

Lyme disease can cause serious harm, but so can bogus tests and treatments.

Vision happens when patterns of light entering the eye are converted into reliable patterns of brain activity. This reliability allows the brain to recognize the same object each time it is seen. Our brains, however, are not born with this ability; instead, we develop it through visual experience. Collaborating scientists at MPFI and the Frankfurt Institute for Advanced Studies have recently discovered key circuit changes that lead to the maturation of reliable brain activity patterns.

The number of Michigan children whose parents died from overdose, suicide, homicide or other substance-related causes has surged since 2000, accounting for 2 in 5 parental deaths, a new University of Michigan study found.