How vitamin D reduces liver damage by boosting TXNIP activity in bile duct cells

There was a time, just a couple of decades ago, when researchers in psychology and health always had to engage with people face-to-face or using the telephone. The worst case scenario was sending questionnaire packs out to postal addresses and waiting for handwritten replies.

A high-resolution ultrasound device has shown great accuracy in detecting suspected meningitis in newborns and infants, potentially offering a noninvasive alternative to lumbar puncture, the traditional diagnostic method. This is the main conclusion of an international study led by the Barcelona Institute for Global Health (ISGlobal), in collaboration with hospitals in Spain, Mozambique, and Morocco. The results have been published in the journal Pediatric Research.

Previous expectations can influence how much pain people eventually feel. These expectations can be shaped by external cues or by verbal information from clinicians about how treatments might relieve pain. Led by Lauren Atlas, researchers from the National Institutes of Health explored if and how distinct ways of shaping expectations differentially influence physically hurtful experiences.

Detecting early rising Parkinson's disease (PD) symptoms could improve treatment outcomes by enabling earlier treatment interventions. In a new eNeuro paper, Daniil Berezhnoi, from Georgetown University, and colleagues used machine learning technology to detect subtle, early rising behavioral changes in mouse models of PD.

Would you dab perfume on a six-month-old? Paint their tiny nails with polish that contains formaldehyde? Dust bronzer onto their cheeks?

Today at ADLM 2025 (formerly the AACC Annual Scientific Meeting & Clinical Lab Expo), researchers will unveil a blood test developed with the help of artificial intelligence (AI) that identifies Lyme disease sooner and more accurately than the current standard—and that could translate to vastly improved patient outcomes. A second study highlights how certain generative AI tools can empower adolescents by helping them to gather useful medical information.

A new study from Karolinska Institutet shows that health care workers in Sweden have a higher risk of suicide compared to other occupational groups with similar professional levels. The study highlights the risks for physicians, registered nurses, and assistant nurses in particular.

The US Food and Drug Administration recently convened a panel of experts to examine a sensitive and increasingly urgent question: should antidepressants be prescribed to women suffering from depression during pregnancy?

Osteoblasts are specialized bone cells responsible for building and regenerating bone tissue. Researchers at Leipzig University have shown that a specific receptor plays a key role in the strength of bone cells—and how this receptor can be selectively activated. These findings could pave the way for the development of new medications with fewer side effects to help strengthen bones and muscles in aging patients. The research has been published in the journal Signal Transduction and Targeted Therapy.

There's something oddly luxurious about sleeping in. The sun filters through the curtains, the alarm clock is blissfully silent, and your body stays at rest. Yet sleeping in is often treated as an indulgence, sometimes framed as laziness or a slippery slope to soft living.

New research by a University of Michigan psychologist and colleagues makes the strongest case yet that ultra-processed foods—including chips, cookies, soda and other heavily engineered products—aren't just tempting; they can actually be addictive.

Millions of people who recover from infections like COVID-19, influenza and glandular fever are affected by long-lasting symptoms. These include chronic fatigue, brain fog, exercise intolerance, dizziness, muscle or joint pain and gut problems. And many of these symptoms worsen after exercise, a phenomenon known as post-exertional malaise.

I saw it firsthand after my cat Murphy died earlier this year. She'd been diagnosed with cancer just weeks before.

A new study has estimated, for the first time, the number of children born globally with hepatitis C virus. The research, led by researchers from the National Institute for Health Research Health Protection Research Unit in Evaluation and Behavioral Science (NIHR HPRU EBS) at the University of Bristol, estimated that each year around 74,000 children globally are born with hepatitis C virus (HCV), with around 23,000 of these children estimated to still have HCV infection at age five.

New research from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King's College London, in partnership with University College London and Anna Freud, has found that negative school experiences generate twice the emotional burden in autistic and ADHD adolescents compared to their neurotypical classmates, and that this is significantly correlated with depression and anxiety.

When you're sick you'll often produce more phlegm, and might notice it's thicker or a different color: white, green, yellow or maybe even brown.

Solitary drinking has soared among young adults, climbing to rates not seen since the late 1970s.

An international study casts doubt on the widespread belief that higher levels of formal education directly protect against cognitive decline and brain aging. The study analyzed longitudinal data from more than 170,000 people in 33 western countries, making it one of the largest studies of cognitive aging to date.