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Immune aging may be a driver of rheumatoid arthritis rather than a consequence

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  • 2025-09-09 02:41 event
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Immune aging may be a driver of rheumatoid arthritis rather than a consequence
Features of immune system aging can be detected in the earliest stages of rheumatoid arthritis (RA), even before clinical diagnosis, a new study has found which provides at-risk individuals with hope for early intervention.

748. A hormone combination improves strength and function in FSHD patients

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New research has demonstrated that a combined regimen of growth hormone and testosterone is safe, well-tolerated, and is associated with meaningful improvements in muscle mass, strength, and mobility for men living with facioscapulohumeral muscular dystrophy (FSHD). Researchers believe that this regimen could benefit patients with other forms of muscular dystrophy.

749. Scientists reprogram cancer-protecting regulatory T cells to fight tumors

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Indiana University School of Medicine scientists have developed a new method that shifts the behavior of immunosuppressive cells in tumors, turning them from cancer protectors into tumor fighters.

750. GERD may be linked to ear disorders, including tinnitus, Meniere disease

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Gastroesophageal reflux disease (GERD) may be associated with an increased risk for tinnitus, Meniere disease, vestibular dysfunction, and sensorineural hearing loss, according to a study published online Aug. 20 in the Journal of Multidisciplinary Healthcare.

751. A new tool can predict the infection risks oral mucositis poses to stem cell transplant patients

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University at Buffalo researchers and collaborators have completed a series of studies that reveal how much painful mouth sores known as oral mucositis increase infection risks in stem cell transplant patients and how artificial intelligence can be used to more accurately predict those risks.

752. Novel 'metabolic clock' could help detect early signs of disease and accelerated aging

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What if a simple blood test could tell how fast you're really aging, or warn you of potential health issues before symptoms appear? A team of scientists from CIC bioGUNE, member of BRTA, led by Prof. José M. Mato, General Director of the center, and Dr. Óscar Millet, head of the Precision Medicine and Metabolism Laboratory, has developed a metabolic aging clock that does just that.

753. Aspirin therapy proves ineffective in treating chronic rhinosinusitis with nasal polyps

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A randomized placebo-controlled Finnish study showed that aspirin therapy does not provide significant relief for people suffering from chronic rhinosinusitis with nasal polyps who are hypersensitive to non-steroidal anti-inflammatory drugs (NSAIDs). The results of a joint study performed by the University of Eastern Finland, University of Helsinki and HUS Inflammation Center were published in the journal Allergy.

754. Blowing off steam at work carries a cost but builds connections

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When something happens in life that you want to vent about, most people have a go-to listener. Being this person for others serves an important purpose in the workplace, providing emotional and problem-focused support.

755. Here's how sleep strengthens muscle and bone by boosting growth hormone levels

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As every bodybuilder knows, a deep, restful sleep boosts levels of growth hormone to build strong muscle and bone and burn fat. And as every teenager should know, they won't reach their full height potential without adequate growth hormone from a full night's sleep.

756. The critical role of movement in lifelong bone health

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A new review by the International Osteoporosis Foundation (IOF) Rehabilitation Working Group underscores the powerful impact of lifestyle behaviors—specifically physical activity and sedentary behavior—on bone health across the human lifespan.

757. Immune aging may be a driver of rheumatoid arthritis rather than a consequence

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Features of immune system aging can be detected in the earliest stages of rheumatoid arthritis (RA), even before clinical diagnosis, a new study has found which provides at-risk individuals with hope for early intervention.

758. First genetically engineered cancer model in naked mole rats

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Researchers at Moffitt Cancer Center have created the first genetically engineered model of lung cancer in naked mole rats, a species long thought to be resistant to cancer. The findings, published in Cancer Discovery, shed light on how cancer begins in this unusual rodent and may reveal new parallels to tumor development in humans.

759. Wireless neural interface could be used for drug delivery to deep brain regions

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A research team has developed an implantable wireless neural interface capable of delivering drugs precisely to deep regions of the brain.

760. Disabling the 'self-destruct button' that causes lung damage in flu

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Influenza (flu) can be fatal, but just how it causes severe damage to the lungs has been a mystery—until now.

761. AI approach paves way for smarter T-cell immunotherapy and vaccine development

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Researchers have harnessed the power of artificial intelligence to tackle one of the most complex challenges in immunology: predicting how T cells recognize and respond to specific peptide antigens. Using AlphaFold 3 (AF3), an AI/ML model, designed for protein structure prediction, the team demonstrated a novel approach to model T cell receptor–peptide/major histocompatibility complex (TCR-pMHC) interactions with growing accuracy. The paper is published in the journal Frontiers in Immunology.

762. Scientists discover why the flu is more deadly for older people

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Scientists have discovered why older people are more likely to suffer severely from the flu, and can now use their findings to address this risk.

763. Children receiving biofeedback speech therapy improve faster than with traditional methods, study finds

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Run. Red. World. Pronouncing the "r" sound in these words requires precise control of the tongue. For most children, this happens naturally, but many children struggle with residual speech sound disorder (RSSD) in which speech errors persist past the age of eight.

764. Only 1 in 7 online health images show proper technique to accurately measure blood pressure

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Only one in seven online stock photo images of blood pressure monitoring correctly show how blood pressure should be measured, contributing to potentially inaccurate readings at home and in physicians' offices, health care facilities or hospitals, according to new research published in Hypertension.

765. Non-hormonal biomaterial could help combat vaginal changes associated with menopause

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A new hydrogel applied directly to vaginal tissues may help alleviate the negative impacts of menopause, according to a new study from scientists at the University of California San Diego. The results, published in Advanced Materials, could pave the way for a hormone-free treatment that alleviates vaginal dryness and pain caused by genitourinary syndrome of menopause (GSM), which negatively impacts quality of life for millions of women.

766. Fertility treatment progress linked to complex communication occurring in ovary

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Women's fertility is influenced not only by the quality of their eggs but also by the interactions between somatic cells in the ovary. A recent study by TalTech researchers, conducted in international collaboration, provides a better understanding of how different ovarian cells exchange information. This knowledge is crucial for advancing fertility treatments.

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