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Incurable blood cancer tied to gene mutation in new lab model

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  • 2025-07-04 02:30 event
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Incurable blood cancer tied to gene mutation in new lab model
Researchers working on an incurable blood cancer can now use a new lab model that could make testing potential new treatments and diagnostics easier and quicker, new research has found.

1.262. Community vaccination effort linked to 25% drop in pneumonia-related mortality among the elderly

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A research team has evaluated the real-world impact of a community-based pneumococcal vaccination support program for older adults conducted in Sera Town, Hiroshima Prefecture, Japan.

1.263. Combined therapy integrates Chinese herb Astragalus and methotrexate to address drug resistance in autoimmune diseases

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Researchers at the School of Chinese Medicine, LKS Faculty of Medicine, the University of Hong Kong (HKUMed), have found that combining the active ingredient extracted from the traditional Chinese medicine Astragalus membranaceus (huang qi) with the widely used Western drug methotrexate (MTX) can effectively reduce chronic inflammation in autoimmune diseases such as systemic lupus erythematosus and Sjögren's disease.

1.264. A new drug causes nerve tissue to emit light, enabling faster, safer surgery

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When surgeons dissect tissue to remove a tumor or make a repair, they must work cautiously, relying on electrophysical monitors and their own anatomical knowledge to avoid cutting nerves, which could complicate the patient's recovery.

1.265. New evidence shows that timely introduction of peanuts and eggs reduces allergy risks

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Families who introduce peanut butter and eggs to their baby's diet at about six months of age can significantly reduce the chances of them developing a life-threatening allergy, according to a study published in the Journal of Allergy and Clinical Immunology: In Practice.

1.266. Gaps in detection and prevention leave many vulnerable to first-time heart attacks

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Despite the global implementation of clinical algorithms designed to predict atherosclerotic cardiovascular disease based on traditional risk factors, the burden of this condition continues to rise. This is shown in a study by ACS researcher Nick Nurmohamed, in close collaboration with Mount Sinai.

1.267. Informal use of antibiotics to prevent sexually transmitted infections on the rise in key populations in the Netherlands

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New research analyzing an online survey of 1,633 respondents found a 15% recent use of doxycycline post- and pre‐exposure prophylaxis (doxyPEP/PrEP) among men who have sex with men (MSM), transgender and gender-diverse people in the Netherlands.

1.268. T cells take aim at Chikungunya virus

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A new study, published recently in Nature Communications, offers the first-ever map of which parts of the Chikungunya virus trigger the strongest response from the body's T cells.

1.269. NAD⁺, zombie cells and the battle against premature aging

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Did you know that a small molecule called NAD+ plays a critical role in our aging process? A deficiency of this molecule may cause you to age much faster than normal.

1.270. Physical activity patterns found to differ by sex and education level

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A recent study published in the Journal of Physical Activity and Health reveals that physical activity and sedentary behavior vary significantly by sex and educational level, but less so by the presence of chronic disease. The study, conducted by researchers at Karolinska Institutet, provides important insights into how different populations engage in physical activity and sedentary behavior.

1.271. Incurable blood cancer tied to gene mutation in new lab model

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Researchers working on an incurable blood cancer can now use a new lab model that could make testing potential new treatments and diagnostics easier and quicker, new research has found.

1.272. Uncertainty—not just social context—drives brain activity when we 'read the minds' of others, psychologists find

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Imagine you are about to confront a friend about a hurtful comment she made and are trying to predict her response. Depending on what you know about your friend, you might infer that she will understand where you're coming from and apologize, get defensive, or respond with criticism of you.

1.273. COVID data transformed disease projection models—researchers explain what's next

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Scientists sometimes compare predicting the course of epidemics to forecasting the weather. But there's a major difference—the impact of human behavior—says Alessandro Vespignani, director of Northeastern University's Network Science Institute.

1.274. Tons of turkey bacon products recalled due to possible listeria contamination

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Kraft Heinz Foods is recalling some 370,000 pounds of fully cooked turkey bacon products that may be contaminated with listeria, the U.S. Department of Agriculture's (USDA) Food Safety and Inspection Service said.

1.275. Hypertension deaths from excessive alcohol use are increasing, study finds

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The estimated mean annual number of hypertension deaths from excessive alcohol use was higher in 2020–2021 than in 2016–2017, with a higher increase among women than men, according to a study published in the July issue of the American Journal of Preventive Medicine.

1.276. Time-restricted eating does not impact sleep, mood, quality of life: Study

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For adults with overweight or obesity, time-restricted eating (TRE) does not lead to significant changes in sleep, mood, or quality of life, regardless of the timing of the eating window, according to a study published online June 25 in JAMA Network Open.

1.277. Simple blood test detects unique glycan linked to schizophrenia diagnosis

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A group from Nagoya University in Japan has developed a simple, accurate, and sensitive method for measuring polysialic acid, a unique acidic glycan found in the brain. Polysialic acid fluctuates in the blood of patients with psychiatric disorders.

1.278. Rare kidney cancer resists immune therapies due to lack of active T-cells

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Cancer-fighting T-cells, the immune system's primary enforcers, are scarce in the rare kidney cancer called chromophobe renal cell carcinoma (ChRCC) and those that are present are indifferent to the tumor threat and traditional immune therapies, revealing the need for new targets and treatments.

1.279. New neurons continue to form in the adult human hippocampus: Study

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A study in the journal Science presents compelling new evidence that neurons in the brain's memory center, the hippocampus, continue to form well into late adulthood. The research from Karolinska Institutet in Sweden provides answers to a fundamental and long-debated question about the human brain's adaptability.

1.280. Alveolar macrophage cell surface receptor TREM2 promotes lung fibrosis, study shows

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Lung macrophages play a pivotal role in diseases like idiopathic pulmonary fibrosis. Two types of macrophages—the white blood cells that defend the body by killing microbes, removing dead cells and stimulating immune responses—are found in the lung. They are tissue resident macrophages, which are present from birth, and monocyte-derived macrophages that enter the lungs for a short time in response to damage or infection.

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