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Kidney atlas maps molecular landscape, unlocking clues to renal health and disease

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  • 2025-06-18 01:29 event
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Kidney atlas maps molecular landscape, unlocking clues to renal health and disease
The kidney, a critical organ for waste filtration and fluid regulation, is the subject of a molecular mapping project that could reshape our understanding of renal health. Despite advances in transcriptomics and proteomics, lipids—key structural and signaling molecules—have remained relatively unexplored in the context of kidney function.

2.818. Electronic nudge letters do not improve guideline-directed medical therapy in CKD

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Neither delivery of electronic nudge letters nor letters to general practice increase uptake of guideline-directed medical therapy (GDMT) among patients with chronic kidney disease (CKD), according to a study published online June 7 in Circulation.

2.819. Mapping tick antiviral responses: Newly identified proteins could help stop deadly fever virus spread

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Researchers from Liverpool School of Tropical Medicine have helped uncover how ticks mount a defense against a deadly virus increasingly found in parts of East Asia, a discovery that could help disrupt disease transmission.

2.820. Adolescent drug trial supporting use of medication for depression reanalyzed

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A highly cited trial from 2007 used by international health agencies to support the use of medication for adolescents with depression has been critically reviewed by a team from the University of Adelaide.

2.821. Prescribing fewer antibiotics might not be enough to combat threat of 'superbugs,' says new research

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Antimicrobial resistance is still spreading in the environment despite a reduction in the amounts of antibiotic drugs prescribed, according to a new study led by the University of Bath. Researchers warn that multiple approaches will be required to tackle the increasing threat of antimicrobial resistance to public health.

2.822. Diabetes during pregnancy linked to increased fetal heart fat

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Diabetes during pregnancy—whether pre-existing or gestational—may lead to increased fat accumulation around the fetal heart, according to a new meta-analysis published in Biomolecules and Biomedicine. The findings suggest a possible early marker for future cardiometabolic disorders in children born to mothers with diabetes.

2.823. More women can now get answers about their hereditary risk of breast and ovarian cancer with genetic method

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There may be hopeful news ahead for families with a history of breast and ovarian cancer.

2.824. More family doctors are nearing the age of retirement, raising concern about future of primary care

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A new ICES study has found that 1.74 million patients in Ontario are attached to family physicians aged 65 or older, and that many of those patients are elderly and have complex medical needs.

2.825. Study finds fatty liver—but not liver damage—common in type 2 diabetes

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Six out of 10 people with type 2 diabetes had fatty liver in a new study from Linköping University. Of these, only a small percentage had developed more severe liver disease.

2.826. Aquatic therapy can heal muscles and minds of people with chronic low back pain, study suggests

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A new Concordia study suggests that aquatic therapy for individuals with chronic low back pain can do more than strengthen the muscles around the spine. It can also have a beneficial impact on the negative psychological factors that are often associated with the disabling disease.

2.827. Kidney atlas maps molecular landscape, unlocking clues to renal health and disease

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The kidney, a critical organ for waste filtration and fluid regulation, is the subject of a molecular mapping project that could reshape our understanding of renal health. Despite advances in transcriptomics and proteomics, lipids—key structural and signaling molecules—have remained relatively unexplored in the context of kidney function.

2.828. Atherosclerotic blood vessel cells grow similar to tumors, study reveals

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Researchers from the University of Southern Denmark and Odense University Hospital have studied tissue from patients with atherosclerosis. They found that many of the cells in the diseased tissue carried the same genetic alteration and appeared to originate from a single ancestral cell that had divided repeatedly—a pattern otherwise associated with tumor biology.

2.829. 'Active breaks' can combat the health risks of a sedentary lifestyle, but what kind of exercise is best?

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Technological advances and the habits of modern life have drastically reduced levels of physical activity around the world. The World Health Organization (WHO) now warns that inactivity and sedentary lifestyles are one of the main risk factors for health problems and premature death.

2.830. Doula and midwife support for mothers in the neonatal intensive care unit improves postpartum care

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In a new study, researchers at Children's Hospital of Philadelphia (CHOP) showed that partnering with doulas and midwives to support mothers with newborns in the Neonatal Intensive Care Unit (NICU) significantly improves access to timely, essential health services during a critical period of care. The findings were reported in the American Journal of Obstetrics & Gynecology MFM.

2.831. Study finds proximity to harmful algal blooms shortens life span in ALS patients

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Living close to cyanobacterial harmful algal blooms—which are present nationwide but are more common in coastal and Great Lakes states—heightens the rate of dying from amyotrophic lateral sclerosis, or ALS, a study suggests.

2.832. When developing countries band together, lifesaving drugs become cheaper, easier to buy... with trade-offs

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Procuring lifesaving drugs is a daunting challenge in many low- and middle-income countries. Essential treatments are often neither available nor affordable in these nations, even decades after the drugs entered the market.

2.833. Higher body mass index could lead to risk for complications after bariatric surgery

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The higher a person's body mass index (BMI), the higher their risk for complications after bariatric surgery, especially those with BMI of 50 or more, according to a new study presented today at the American Society for Metabolic and Bariatric Surgery (ASMBS) 2025 Annual Scientific Meeting.

2.834. Immune 'dysregulation' present prior to infection can predict severe responses

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At the start of the COVID-19 pandemic, information began to trickle in about who was at higher risk of a dangerous outcome from infection: men, those over 65, smokers, those with obesity. It turns out these seemingly unrelated categories of people have one thing in common: a signature of immune dysregulation.

2.835. When you lose your health insurance, you may also lose your primary doctor, and that hurts your health

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When you lose your health insurance or switch to a plan that skimps on preventive care, something critical breaks.

2.836. Chronic pain hits rural residents hardest, according to study

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A new study from The University of Texas at Arlington reveals that people who live in rural areas are more likely to have chronic pain than those in urban settings. They're also more likely to go from having no pain or occasional pain to chronic pain. The findings may help explain higher opioid prescription rates in rural communities and could guide future research into the root causes of this disparity.

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