Kidney cancer cases are projected to double by 2050, says study

An mRNA vaccine developed by researchers from Japan suppressed abnormal blood vessel growth or neovascularization in the retina of mouse models. Neovascularization is a condition that is caused by age-related macular degeneration (AMD), a leading cause of vision loss for elderly people. The vaccine can be delivered intramuscularly and is as effective as current therapies that require frequent eye injections, offering a more comfortable and easier-to-administer alternative for treating AMD and other neovascular eye diseases.

Cultured neural tissues have been widely used as a simplified experimental model for brain research. However, existing devices for growing and recording neural tissues, which are manufactured using semiconductor processes, have limitations in terms of shape modification and the implementation of three-dimensional (3D) structures.

Initial and follow-up 3D digital scans provide new insights into the effects of hyaluronic acid (HA) fillers in restoring facial volume and fullness, reports a study in the October issue of Plastic and Reconstructive Surgery.

The SCoRE tool developed at the University of Würzburg reliably records the soccer skills of girls in real game situations for the first time. It is available as an app for coaches.

High-grade gliomas are aggressive brain tumors with poor prognosis, largely because even after surgical removal, infiltrative residual tumor cells often regrow during the latency before radiotherapy, leading to recurrence. The standard chemoradiotherapy only modestly improves survival. A crucial window of vulnerability arises post-surgery, before radiotherapy begins, where residual tumor cells are not well addressed by systemic chemotherapy.

Researchers at the University of Michigan are using artificial intelligence to predict the health consequences that sport-related concussions might have on student athletes over the course of their college athletic careers.

When a sperm meets an egg, a lot has to go right for an embryo to develop into a complete organism. One critical step of early development is the reorganization of parental DNA to form a new unified genome, before the embryo can undergo its first cell division.

Rabies is one of the deadliest infectious diseases, but it is also preventable when treated quickly after an animal bite. A new post-licensure clinical study published in The Lancet further demonstrates that Rabishield, a monoclonal antibody therapy developed by UMass Chan Medical School in partnership with the Serum Institute of India, offers a safe and effective alternative to older rabies treatments.

DMT, or dimethyltryptamine, is a natural psychoactive molecule found in many plants and mammals. According to an article published in Science Advances, researchers from the HUN-REN BRC Institute of Biophysics and Semmelweis University Heart and Vascular Center found that DMT reduces the harmful effects of stroke in animal models and cell culture experiments.

Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers, with a five-year survival rate below 10%.

Globally recognized figures Muhammad Ali and Michael J. Fox have long suffered from Parkinson's disease. The disease presents a complex set of motor symptoms, including tremors, rigidity, bradykinesia, and postural instability. However, traditional diagnostic methods have struggled to sensitively detect changes in the early stages, and drugs targeting brain signal regulation have had limited clinical effectiveness.

Researchers from The University of Texas MD Anderson Cancer Center will present new data at the American Society for Radiation Oncology (ASTRO) 2025 Annual Meeting demonstrating that stereotactic body radiation therapy (SBRT) and surgery achieved similar survival outcomes at 10-year follow-up for patients with early-stage non-small cell lung cancer, with radiation offering quality-of-life benefits. These findings will be presented Sept. 29 by Joe Chang, M.D., Ph.D., professor of Radiation Oncology, and Troy Kleber, M.D., resident.

Newcastle researchers have revealed the first treatment to target the underlying cause of a rare kidney condition called "C3G" and prevent the disease progressing.

Global health research has long shown the devastating consequences that maternal deaths have on families and communities in developing countries where maternal mortality rates are high. But this insight is rare in the United States, despite the nation maintaining the highest rate of maternal mortality among its peer nations.

West Nile virus is the leading cause of mosquito-borne illness in the continental United States. As of Sept. 23, over 1,100 human cases of West Nile disease have been reported across 42 states, according to the U.S. Centers for Disease Control and Prevention (CDC), including nearly 750 cases of the more serious neuroinvasive form which affects the brain.

An international research team led by Université de Montréal medical professor Shady Rahayel has made a major breakthrough in predicting neurodegenerative diseases.

How humans move is an open question, according to Mark Latash, distinguished professor of kinesiology at Penn State.

The cumulative effect of social advantages across a lifetime—from parental warmth in childhood to friendship, community engagement and religious support in adulthood—may slow the biological processes of aging itself. These social advantages appear to set back "epigenetic clocks" such that a person's biological age, as measured by analyzing DNA methylation patterns, is younger than their chronological age.