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Long-term remission of advanced liver cancer in 46% of patients achieved with combination therapy

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  • 2025-05-25 21:10 event
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Long-term remission of advanced liver cancer in 46% of patients achieved with combination therapy
An interdisciplinary research team has demonstrated a durable and lasting response to a novel treatment—combined locoregional therapy and immunotherapy (LRT-IO)—for advanced liver cancer patients. The study marks the first investigation into the long-term outcomes for patients with locally advanced liver cancer receiving this treatment. The researchers identified key factors associated with a complete response, and found that this pioneering approach is safe, effective and sustainable.

2.414. Study offers new hope for safer bleeding treatments

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A new study from UNC School of Medicine researchers, published this week in Blood, provides fresh insight into how the body forms and dissolves blood clots—and may help reshape how doctors treat patients at risk of bleeding.

2.415. How likely is a new pandemic in the future? Here's what Americans said in a poll

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In 2020, COVID-19 began spreading rapidly across the U.S., leading to major shutdowns and radically altering the lives of millions. Now, five years later, most Americans think the country could be plagued by a new pandemic, according to recent polling.

2.416. FDA approves Nucala for chronic obstructive pulmonary disease

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The U.S. Food and Drug Administration has approved GSK's Nucala (mepolizumab) as an add-on maintenance treatment for adult patients with inadequately controlled chronic obstructive pulmonary disease (COPD).

2.417. No sex differences in autistic toddlers at time of first diagnosis, study finds

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Males are more than four times more likely to receive an autism diagnosis than females. But a new study by researchers at UC San Diego School of Medicine has found no clinical differences in autistic traits between the sexes in toddlers when they are first diagnosed with autism.

2.418. Trump exaggerates speed and certainty of prescription drug price reductions

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Under a new executive order, prescription drug prices will be reduced "almost immediately."

2.419. Genetic investigations reveal reason for severe neuropathy after infection

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Neuropathy, a disorder in which damage to nerves can impair sensation and movement, has many causes, including infection. Now, researchers from the UK have identified distinct genetic changes in a newly-discovered neuropathy and believe that their work will provide insights into the causal mechanism and why some previously healthy people develop neuropathies after infection whereas others do not.

2.420. Just three nights of poor sleep might harm your heart: New study

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We've long known that a lack of sleep is bad for the heart—but scientists are now starting to understand exactly how it causes harm.

2.421. How abortion laws focusing on fetal viability miss the mark on women's experiences

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During the 2024 presidential campaign, politicians and their surrogates repeatedly raised concerns about abortion later in pregnancy. The topic grabbed media attention and continues to inspire strong emotions, but most of the discussions include numerous misunderstandings.

2.422. Intravenous tenecteplase beneficial before endovascular thrombectomy

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For patients with acute ischemic stroke due to large-vessel occlusion who present within 4.5 hours, intravenous tenecteplase before endovascular thrombectomy is associated with higher functional independence at 90 days, according to a study published online May 21 in the New England Journal of Medicine to coincide with the annual European Stroke Organisation Conference, held from May 21 to 23 in Helsinki.

2.423. Long-term remission of advanced liver cancer in 46% of patients achieved with combination therapy

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An interdisciplinary research team has demonstrated a durable and lasting response to a novel treatment—combined locoregional therapy and immunotherapy (LRT-IO)—for advanced liver cancer patients. The study marks the first investigation into the long-term outcomes for patients with locally advanced liver cancer receiving this treatment. The researchers identified key factors associated with a complete response, and found that this pioneering approach is safe, effective and sustainable.

2.424. West Nile virus found in the UK for the first time: What you need to know

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For the first time, traces of the West Nile virus have been found in mosquitoes in the UK, according to a report published this week by the UK Health Security Agency.

2.425. Sierra Leone reports more than 3,000 mpox cases, 14 deaths

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The number of cases of mpox registered in Sierra Leone since the beginning of the year has hit 3,011, with 14 dead of the disease, according to new government data.

2.426. You should wear sunscreen even if you have darker skin. Here's why

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People with darker skin still need to wear sunscreen—for more reasons than one.

2.427. Working women are too often left to deal with endometriosis alone. But big changes could be coming

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Endometriosis is a long-term and invisible gynecological condition that affects around 1.5 million women in the UK alone. It's known for its unpredictable and debilitating symptoms, like chronic pelvic pain, heavy periods and fatigue. But many women face outdated practices in the workplace that just don't accommodate the reality of the condition.

2.428. Early prediction of preterm birth in cell-free RNA could reshape prevention strategies

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Children born before 37 weeks of gestation have a considerably increased risk of dying before they reach the age of five. Predicting the risk of preterm birth (PTB) and hence implementing preventive strategies is complicated by the heterogeneity of the condition, the many unknown mechanisms involved, and the lack of reliable predictive tools.

2.429. Swept-source anterior segment optical coherence tomography can help distinguish early childhood glaucoma

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The noninvasive swept-source anterior-segment optical coherence tomography (SS-ASOCT) can diagnose early-onset childhood glaucoma, according to a study published online May 22 in JAMA Ophthalmology.

2.430. Hay fever: Why symptoms are so bad this year, and what to do if your usual remedies aren't working

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Hay fever can be annoying at the best of times. But this year, many people are reporting their usual symptoms are worse than ever before—with their normal go-to remedies doing little to provide relief.

2.431. Using testosterone gel to treat women recovering from hip fractures provides no added benefits, clinical trial finds

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Hip fractures, often a result of a fall, are the most serious type of osteoporotic fracture because they are accompanied by considerable pain, loss of muscle and bone strength, reduced mobility and independence with daily activities, and increased risk for future fractures and death. More than 200,000 American women every year experience hip fractures, and up to three-quarters of them never fully regain their ability to resume normal activities like walking, even after undergoing weeks of exercise rehabilitation.

2.432. 3D-printed device enables precise modeling of complex human tissues in the lab

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A new, easily adopted, 3D-printed device will enable scientists to create models of human tissue with even greater control and complexity. An interdisciplinary group of researchers at the University of Washington and UW Medicine led the development of the device.

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