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Many patients with high-risk myelodysplastic syndromes miss out on effective treatment, study finds

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  • 2025-08-06 21:00 event
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Many patients with high-risk myelodysplastic syndromes miss out on effective treatment, study finds
Most patients with high-risk myelodysplastic syndromes (MDS) do not receive guideline-recommended treatment with hypomethylating agents (HMAs), according to results published in Blood Neoplasia. The findings suggest that underuse of these drugs may help explain why MDS outcomes have not improved over the past two decades since these life-extending medications became available.

559. Can you trust AI for stroke care? Not yet, say scientists

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Scientists have found that three language-model chatbots—even with advanced prompt-engineering tricks—often give suboptimal guidance across stroke prevention, diagnosis, treatment and recovery, highlighting the need for human oversight to ensure appropriateness and safety. Stroke remains a leading cause of death and disability worldwide, underscoring the urgency for accurate and actionable patient guidance.

560. 3D-printed cardiac patch encourages tissue repair using structural mesh and hydrogel with living cells

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A new type of tissue-engineered cardiac patch could not only seal defective areas of the heart, as has been the case up to now, but also heal them. An interdisciplinary team led by ETH Zurich has successfully implanted the patch in animals.

561. Dizzy, heart racing after you stand? New treatment proposed

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Some people find that when they stand, their hearts tend to race and they get dizzy and lightheaded.

562. Cardiac arrest can happen suddenly—here's everything you need to know

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Cardiac arrest is defined as a sudden stop in heart function. Essentially, the pumping function of the heart is compromised, oftentimes due to a dangerous malfunction of the heart's electrical system.

563. AI chatbots can run with medical misinformation, highlighting need for stronger safeguards

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A new study by researchers at the Icahn School of Medicine at Mount Sinai finds that widely used AI chatbots are highly vulnerable to repeating and elaborating on false medical information, revealing a critical need for stronger safeguards before these tools can be trusted in health care.

564. From arthritis to nausea: Five ways ginger could benefit your health

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From warming winter teas to zesty stir-fries, ginger (Zingiber officinale) has long been a kitchen staple. But beyond its culinary charm, this spicy root has a rich history in traditional medicine—and modern science is catching up. Studies now show that ginger may offer a wide range of health benefits, from easing nausea and relieving colds to reducing inflammation and supporting heart health.

565. Could we one day get vaccinated against the gastro bug norovirus? Here's where the science stands

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Norovirus is the leading cause of acute gastroenteritis outbreaks worldwide. It's responsible for roughly one in every five cases of gastro annually.

566. Why the search for meaning can cause 'purpose anxiety,' and what to do about it

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"Find your purpose." It has become such common advice that few question it. But rather than inspirational, it can feel like a burden. How do I go about finding this and what if I never do?

567. First gene-edited islet transplant in a human passes functional trial

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Uppsala University Hospital-led investigators report that gene-edited donor islet cells survived 12 weeks inside a man with long-standing type 1 diabetes without any immunosuppressive medication.

568. Many patients with high-risk myelodysplastic syndromes miss out on effective treatment, study finds

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Most patients with high-risk myelodysplastic syndromes (MDS) do not receive guideline-recommended treatment with hypomethylating agents (HMAs), according to results published in Blood Neoplasia. The findings suggest that underuse of these drugs may help explain why MDS outcomes have not improved over the past two decades since these life-extending medications became available.

569. Air purifiers may reduce heart risks for people exposed to traffic pollution

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Using portable high-efficiency particulate air (HEPA) purifiers at home can significantly lower systolic blood pressure (SBP) in adults with elevated baseline readings—even in areas with relatively low overall air pollution levels, according to a study published in the Journal of the American College of Cardiology.

570. Is it true foods with a short ingredient list are healthier? A nutrition expert explains

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At the end of a long day, who has time to check the detailed nutrition information on every single product they toss into their shopping basket?

571. What your pet's poo can reveal about the spread of antibiotic-resistant superbugs

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Bagging up and disposing of your pet's poo is a necessary, albeit unpleasant, part of responsible pet ownership. But a new UK government initiative will be asking people to send them their pets' poo instead of throwing it away.

572. Mushroom-derived molecule drives microbial chemistry linked to colorectal cancer

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Microbes in our gut are important for overall health, but certain bacteria can promote inflammation, damage DNA, and support the growth of diseases like cancer.

573. Non-antibiotic drugs can also disrupt the microbiome

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Non-antibiotic drugs can alter the microbiome and increase the risk of gut infections in surprising ways, a new Nature study shows.

574. Plastics and human health: What's at stake in the global treaty talks in Geneva

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Plastics are everywhere—they're even in you right now—and are making many of us sick. Now, global negotiators are fighting over whether that matters.

575. Dual imaging capsule captures 3D tissue and blood vessel changes for early esophageal cancer diagnosis

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Researchers from Helmholtz Munich, the Technical University of Munich (TUM), and the Medical University of Vienna have developed an advanced imaging technique called "O2E" that allows clinics to detect cancerous lesions in the esophagus with unprecedented precision.

576. An estimated 17 million US youth meet criteria for GLP-1RA treatment

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A cross-sectional analysis from Yale School of Medicine estimates that approximately 5.8 million adolescents and 11.1 million young adults in the United States meet eligibility criteria for glucagon-like peptide-1 receptor agonists (GLP-1RAs), drugs approved to treat obesity and type 2 diabetes (T2D) in some pediatric populations.

577. Transcatheter edge-to-edge repair associated with improved survival in the elderly patients with blood condition

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The mitral valve controls blood flow between the heart's left atrium and ventricle. When structural changes affect the atrium or valve, it may not close fully—causing blood to leak backwards, a condition known as atrial functional mitral regurgitation (AFMR). Common in frail or elderly patients, AFMR often leads to heart failure, and standard surgery is typically too risky due to other health issues.

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