Mapping overlooked challenges in stroke recovery

Scientists at University College London have engineered a rare type of immune cell to kill slow-growing bowel cancer cells that are resistant to current therapies, a breakthrough that could lead to new treatments in the future.

For people with medical conditions, stigma is a real problem they must worry about on top of their health. Stereotypes about health conditions often cause discrimination even by health care providers, as many may assume those affected don't take care of their health, when in reality they likely have no control over their condition.

Researchers led by Masako Tamaki at the RIKEN Center for Brain Science in Japan report a link between deep sleep and cerebrospinal fluid, the clear liquid that surrounds and supports the brain and spinal cord. Published in Proceedings of the National Academy of Sciences, the study demonstrates how changes in cerebrospinal fluid signals during sleep—as measured by MRI—are time-locked to slow brain waves and other neural events.

Preexisting hyperlipidemia in pregnancy is associated with heightened risks of obstetric complications and early cardiovascular events in the first five years postpartum, according to a new study being presented at ACC's Cardio-Obstetrics Essentials: Team-Based Management of Cardiovascular Disease and Pregnancy conference.

About half of women over 40 have dense breasts. The denser the breast tissue, the more difficult it is to spot cancer on a standard mammogram. Having dense breast tissue can make it harder to detect cancer and sometimes leads to consideration of supplemental screenings along with your mammogram.

When cancer spreads, tiny amounts of cells can break away from tumors and circulate in the bloodstream. A liquid biopsy is a means to detect the presence of cancer by detecting these cancer cells floating in blood samples. However, current state-of-the-art methods have necessitated trained specialists to comb through and review images of thousands of cells out of potentially millions of cells on a slide over a period of many hours.

Researchers from Edith Cowan University (ECU) have developed an innovative new way to measure biological age, which could make it easier to detect and track age-related conditions.

A meta-analysis of randomized trials suggests fecal microbiota transplantation can ease depressive symptoms, with stronger effects reported for endoscopic or enema delivery, according to researchers at the Department of Nursing, Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine. A subset also found improvements in irritable bowel syndrome (IBS).

In addition to linguistic prompts, large language models can also understand, interpret, and adapt their responses to heart frequency data. Dr. Morris Gellisch, previously of Ruhr University Bochum, Germany, and now at University of Zurich, Switzerland, and Boris Burr from Ruhr University Bochum have developed a technical interface through which the physiological data can be transmitted to the language model in real time.

In a study published in Neuron, a research team at the Department of Neurology at Massachusetts General Hospital, aimed to understand how immune cells of the brain, called microglia, contribute to Alzheimer's disease (AD) pathology. It's known that subtle changes, or mutations, in genes expressed in microglia are associated with an increased risk for developing late-onset AD.

New research published in Cell finds the existence of craters on the surface of melanoma cells that serve as immune hubs, becoming major sites for tumor killing. These craters could serve as good markers for immunotherapy success.

A class of antivirals called Pin1 inhibitors could reduce or stop outbreaks of herpes simplex virus 1 (HSV-1), the common infection behind oral herpes, according to new research published in Antiviral Research.

An alliance of scientists at the Broad Institute and Bayer Pharmaceuticals have developed a drug candidate, sevabertinib, that could be a new treatment for a group of lung cancer patients who have few options today.

In recent research, treatment with osimertinib plus a platinum–pemetrexed chemotherapy combination resulted in statistically significant and clinically meaningful improvement in overall survival in patients with newly diagnosed EGFR-mutated advanced non-small cell lung cancer (NSCLC) compared to osimertinib alone.

An out-of-state visitor with a confirmed case of measles may have exposed people at a southern Colorado hotel and gas station earlier this week, according to state and Huerfano County health officials.

Studies have found that the density of tobacco retailers in a neighborhood is associated with smoking, the leading cause of preventable disease and death. But what if smokers and policymakers were able to understand the impact of this exposure not just on a population level but at the individual level? Rather than relying on longer recall periods and assumptions about how people move through their neighborhoods, as many studies do, what if researchers could follow the movements and behaviors of smokers more naturally—hour by hour, day by day?

A newly formed, multistate coalition represents the largest coordinated pushback to federal public health guidance under Health Secretary Robert F. Kennedy Jr. to date.

Volleyball player Madelyn Olympia, 14, started experiencing back pain after diving for a ball.