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Metabolic differences in male and female muscles may explain diabetes variations

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  • 2025-07-08 01:57 event
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Metabolic differences in male and female muscles may explain diabetes variations
The skeletal muscles of men and women process glucose and fats in different ways. A study conducted by the University Hospital of Tübingen, the Institute for Diabetes Research and Metabolic Diseases of Helmholtz Munich and the German Center for Diabetes Research (DZD) e.V. provides the first comprehensive molecular analysis of these differences. The results, published in Molecular Metabolism, possibly give an explanation for why metabolic diseases such as diabetes manifest differently in women and men—and why they respond differently to physical activity.

778. Prenatal alcohol exposure could worsen recovery from stroke in midlife

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Exposure to alcohol in utero can have enduring health effects across the lifespan, including increased risks related to strokes in midlife, according to new research. The preclinical study found that fetal alcohol exposure significantly influences how well someone in middle age will recover after a stroke. Individuals prenatally exposed to alcohol had more inflammatory markers and significantly worse health outcomes immediately following a stroke.

779. Lower sensitivity to alcohol linked to persistent drinking despite negative consequences

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People who experience less stimulation from drinking are more likely to continue seeking alcohol despite its negative consequences, according to a novel study that tested a behavioral model of aversion-resistant drinking. Compulsively using alcohol despite its impact on health and relationships is a key marker of the transition to alcohol use disorder (AUD).

780. Treatment with virtual reality works quickly and effectively for those with psychosis, study shows

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Treatment with virtual reality appears to work very well for people with psychosis. It works faster than the current treatment with cognitive behavioral therapy and is at least as effective.

781. Treating a common bacteria could reduce gastric cancer cases worldwide

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As many as 15.6 million people born between 2008 and 2017 globally are expected to develop gastric cancer sometime in their life, suggests a study published in Nature Medicine.

782. Brain stimulation plus coaching helps older adults double daily steps versus coaching alone

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A study published in The Journals of Gerontology: Series A reports that a novel combination of brain stimulation and personalized coaching significantly increased physical activity in older adults and held steady for months. The results offer hopeful news for inactive older adults living in subsidized housing, who may experience several barriers to increased activity, including depression and a lack of motivation.

783. ISS researcher links bone loss in astronauts to stem cell changes in microgravity

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Mayo Clinic physician and researcher Dr. Abba Zubair's work combines two passions—medicine and space—for the benefit of astronauts and people on Earth. His research in space is yielding discoveries in cancer, stroke, bone loss and more.

784. Children under three can learn new words even when speakers wear masks

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A research team from the Universitat Autònoma de Barcelona (UAB) and the University of Grenoble Alpes—Centre National de la Recherche Scientifique (CNRS) has shown that from the age of two, children can learn new words even when the person talking to them has their mouth or eyes covered.

785. Late eating is associated with impaired glucose metabolism

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Our metabolic processes differ depending on the time of day and many of them are more active in the morning than in the evening. Although studies show that eating late in the day is associated with an increased risk of obesity and cardiovascular diseases, little is known about how the time we eat affects glucose metabolism and to what extent this is genetically defined.

786. Opinion: African surveillance labs can power polio eradication push

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As my term as acting WHO regional director for Africa draws to a close, I have been reflecting on the resilience and collective commitment that have defined our region's fight against polio.

787. Metabolic differences in male and female muscles may explain diabetes variations

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The skeletal muscles of men and women process glucose and fats in different ways. A study conducted by the University Hospital of Tübingen, the Institute for Diabetes Research and Metabolic Diseases of Helmholtz Munich and the German Center for Diabetes Research (DZD) e.V. provides the first comprehensive molecular analysis of these differences. The results, published in Molecular Metabolism, possibly give an explanation for why metabolic diseases such as diabetes manifest differently in women and men—and why they respond differently to physical activity.

788. How war trauma affects Vietnamese Americans' brain health

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As the United States reflects on the 50th anniversary of the end of the Vietnam War this year, researchers from UC Davis and UC San Francisco have uncovered major insight into the trauma and resilience of Vietnamese Americans who fled the conflict and moved to America.

789. Simultaneous kidney and stem cell transplants may enable patients to ditch lifelong immunosuppressants

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While immunosuppressive medications are critical to preventing rejection of transplant organs, they also come with plenty of downsides. They can cause harsh side effects, like headaches and tremors, and increase the risk of infection and cancer. But what if there was a way to prevent organ rejection without using these medications?

790. How kidney transplants might affect pregnancy risks for users of assisted reproductive technology

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Women with kidney transplants who use assisted reproductive technology (ART) to conceive might face higher risks of complications during pregnancy, according to new research from the University of Cincinnati College of Medicine. The study provides some of the first large-scale data on pregnancy outcomes in this unique patient population.

791. How strong is your weed? Study shows labels often misrepresent potency

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Nearly half of cannabis flower products are inaccurately labeled when it comes to potency, with most showing they contain more THC than they really do. Meanwhile, labels on cannabis concentrates like oils and waxes tend to be accurate, with 96% shown to match what's inside.

792. Non-white groups in England and Wales face higher post-COVID heart risks, finds study

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A new study has found that people from non-white ethnic backgrounds in England and Wales continued to be disproportionately impacted by severe outcomes after COVID-19 such as cardiovascular disease.

793. Cancer cells form protective microenvironment against CDK4/6 inhibitors, study shows

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Targeted cancer drugs known as CDK4/6 inhibitors have improved outcomes for patients with advanced or metastatic HR+/HER2- breast cancer, but many patients still eventually relapse and become resistant to therapy. New research co-headed by a Fox Chase Cancer Center scientist helps explain why—and offers three strategies for making treatment more effective.

794. AI-assisted technique can measure and track aging cells

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A combination of high-resolution imaging and machine learning, also known as artificial intelligence (AI), can track cells damaged from injury, aging, or disease, and that no longer grow and reproduce normally, a new study shows.

795. Surgical microscope uses 48 tiny cameras to offer precise 3D imaging

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For over a century, surgeons performing delicate procedures have relied on stereoscopic microscopes to gain a sense of depth. These tools mimic human vision by presenting slightly different images to each eye, allowing the brain to perceive three-dimensional structures—a crucial aid when working with fragile blood vessels or intricate brain tissue. Despite modern upgrades like digital displays and video capture, today's operating microscopes still depend on the same core principle: two views, interpreted by the human brain.

796. Treatment timing is critical to Prozac's impact on mood behaviors

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Researchers have found that the timing of when fluoxetine (commonly known by its brand name, Prozac) is administered is vital in determining the impact it has on long-lasting mood behavior and accompanying changes in the prefrontal cortex. The new study published in Biological Psychiatry provides crucial mechanistic insights into alterations in neurocircuits that regulate mood behavior, which are key to making informed choices in treating depression in children and adolescents.

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