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A new, highly potent class of immunotherapeutics with unique Velcro-like binding properties can kill diverse cancer types without harming normal tissue, University of California, Irvine cancer researchers have demonstrated.
Research published by Duke University researchers has found a strong link between higher stress in children and adverse health conditions for them later in life. Appearing in the journal Proceedings of the National Academy of Sciences, the study used measurable metrics of health over time to create a more quantitative view of how stress early in life affects health.
The mechanism of skeletal muscle contraction is a process that relies on calcium signaling. However, the physiological role of calcium-induced calcium release (CICR) through the ryanodine receptor type 1 (RyR1) has remained unresolved for decades.
Every day for nearly 18 years, Alessandra Fabrello has been a medical caregiver for her son, on top of being his mom.
The first clinical practice guidelines on assessment and management of diabetes distress among adults were presented at the annual meeting of the European Association for the Study of Diabetes, held from Sept. 15 to 19 in Vienna.
The U.S. Food and Drug Administration has granted accelerated approval to Forzinity (elamipretide) injection as the first treatment for Barth syndrome.
Changes in vision are often a common sign of aging. But what if we could reverse age-related visual decline? In a new study, UC Irvine researchers explore a possible therapy for addressing "aging" in the eye and for preventing diseases such as age-related macular degeneration (AMD).
How our bodies break down and remove old and damaged bone tissue is linked to our inner circadian clock, according to a new study from the University of Surrey and the University of Sheffield.
Before a chain of amino acids can become an active and useful protein, it must be processed and folded into the appropriate conformation. Much of this processing occurs in the endoplasmic reticulum (ER) of every cell.
Mucus is more than just a sticky substance: It contains a wealth of powerful molecules called mucins that help to tame microbes and prevent infection. In a new study, MIT researchers have identified mucins that defend against Salmonella and other bacteria that cause diarrhea.
Brazilian researchers, in partnership with French institutions, have developed a tool that can predict how patients will respond to natalizumab, one of the most commonly used drugs for treating multiple sclerosis.
Type 2 diabetes medications, such as sulfonylureas, have been a mainstay of treating the disease since they came on the market in the early 1950s. However, although they are one of the most common drugs for this condition, it is not surprising that they lose effectiveness over time and have been seen to often cause more side effects than other antidiabetic drugs.
A study led by Vincenzo Condello and Christofer Juhlin of the Karolinska Institutet explores why some papillary thyroid cancers don't respond well to radioactive iodine (RAI) therapy—a key treatment used after surgery to eliminate remaining thyroid cancer cells.
Tropical cyclones pose an important risk of death for children under five in low- and middle-income countries, reports a new study led by Renjie Chen of Fudan University, China, published in PLOS Medicine.
Gleevec, a cancer drug first approved for sale in 2001, has dramatically changed the lives of people with chronic myeloid leukemia. This form of cancer was once regarded as very difficult to combat, but survival rates of patients who respond to Gleevec now resemble that of the population at large.
As a deadly new Ebola outbreak kills dozens in southern Congo, health authorities and organizations are sounding the alarm, warning they lack the funds and resources to mount an effective response to the crisis.
In a clinical practice guideline published online Sept. 16 in Practical Radiation Oncology, recommendations are presented for the use of postmastectomy radiation therapy (PMRT).
People with substance dependency may face stigmatization when they attend community pharmacies and deserve to be treated with greater dignity and respect, according to new research.
A new study published in the Journal of Nutrition Education and Behavior highlights the development of a culturally-informed approach to screening for food insecurity among patients at Northern Navajo Medical Center (NNMC) in Shiprock, New Mexico. The alternative screener aims to reduce stigma, improve patient comfort, and reflect local food traditions and community food access better.