Novel enzyme therapy restores hearing in mice with rare genetic bone disorder

A promising new COVID-19 vaccine candidate developed by researchers at the Centenary Institute and the University of Sydney has shown strong potential to protect against both current and emerging coronavirus variants. By targeting features shared by a range of coronaviruses, the vaccine is designed to offer broader and longer-lasting protection as the virus continues to evolve.

Two junior research groups at Ruhr University Bochum, Germany, have developed a drug complex that kills cancer cells in such a clever manner that they raise a red flag as they die. They signal to the immune system that something is seriously wrong with this type of cell.

Teeth may seem like static fixtures, but a new collaboration between engineers and clinicians is proving just how dynamic, informative and medically significant our teeth can be.

Chronic thromboembolic pulmonary hypertension (CTEPH) is the clinical term for high blood pressure in the lungs caused by blockages, such as clots, in the blood vessels. Although CTEPH therapies have improved over recent decades, trends in patient prognosis remain unclear.

In light of reports from the White House that President Donald J. Trump has been diagnosed with chronic venous insufficiency (CVI), the American Heart Association is sharing important information on the condition and its association with cardiovascular risk factors, disease and increased risk of death.

Caffeine, which is present in various foods and beverages, is widely known to improve exercise performance. However, these ergogenic effects may not be observed under hot conditions.

In a first of its kind randomized controlled trial, researchers found delivering a problem-solving digital mental health intervention to young Ukrainian refugees significantly reduced symptoms of depression and anxiety.

In Japan, people spend approximately seven hours sitting per day, which is the longest sitting time in the world. This sedentary behavior (i.e., repeated bouts of prolonged sitting) increases the risk of cardiovascular disease. Recently, a research group has reported that prolonged sitting under constant skin temperature conditions can impair cutaneous vasodilation function, and repeated local heating and cooling do not mitigate this impairment.

Colorado's first human cases of West Nile virus this year were confirmed in two people who contracted the disease in Adams County, public health officials said on July 17.

There are three main types of urinary incontinence:

The U.S. Food and Drug Administration has announced a plan to revoke 52 food standards after concluding they are "obsolete and unnecessary."

The term dementia is used to describe various debilitating neurological disorders characterized by a progressive loss of memory and a decline in mental abilities. Estimates suggest that over 55 million people worldwide are currently living with dementia, and this number could rise further over the next decades.

An experimental mRNA vaccine has boosted the tumor-fighting effects of immunotherapy in a mouse-model study, bringing researchers one step closer to their goal of developing a universal vaccine to "wake up" the immune system against cancer.

As millions of people know firsthand, the most common side effect of mRNA vaccines like the COVID-19 shot is inflammation: soreness, redness and a day or two of malaise. But what if mRNA vaccines could be redesigned to sidestep that response altogether?

In the Canadian town of Aylmer, where Mennonites in traditional dress walk down the main street alongside secular locals, bitter divisions over vaccine skepticism that arose during COVID have intensified with the reemergence of measles.

Vitamin D is not only an essential nutrient, but also the precursor of the hormone calcitriol, indispensable for health. It regulates the uptake of phosphate and calcium necessary for bones by the intestines, as well as cell growth and the proper function of muscles, nerve cells, and the immune system.

Scar tissue in the heart was associated with abnormal heart rhythms among healthy, long-time male endurance athletes aged 50 or older, potentially increasing their risk of sudden cardiac death, according to a small study published in Circulation: Cardiovascular Imaging, an American Heart Association journal.

In a major advance for patients with Crohn's disease, a new study led by researchers at Mount Sinai Health System found that guselkumab, a medication with a mechanism of action that is new to inflammatory bowel disease (IBD) treatment, outperformed an established standard of care in promoting intestinal healing and symptom relief.