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Novel immune cell population may offer alternative target for tuberculosis vaccines

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  • 2025-05-23 21:57 event
  • 2 months ago schedule
Novel immune cell population may offer alternative target for tuberculosis vaccines
There is no highly effective vaccine against tuberculosis (TB), which remains an infection of global concern. Charles Kyriakos Vorkas, MD, an infectious diseases physician-scientist at the Renaissance School of Medicine (RSOM) at Stony Brook University, and colleagues identified a novel population of immune cells that could serve as an alternative target for TB vaccines and immune-directed therapy. Their findings are detailed in a paper published in Scientific Reports.

2.473. Chatbots perceived as more judgmental than human mental health provider counterparts, study suggests

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Recognizing that some people facing mental health issues are not turning to traditional providers for assistance, a Temple University associate professor has examined how artificial intelligence could be leveraged to help improve access to health care resources.

2.474. Millions still lack access to glasses—study shows minimal progress in coverage since 2010

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Millions of people across the world still lack access to basic eye care such as glasses, according to a new study led by Professor Rupert Bourne of Anglia Ruskin University (ARU).

2.475. Single-cell RNA sequencing of bone metastases from multiple cancer types reveals three distinct immune archetypes

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Bone is a common site for metastasis of solid cancers, but histological and molecular features of bone metastases are not well understood. In a new study published in Cell Genomics, researchers at Baylor College of Medicine and the University of Texas MD Anderson Cancer Center use RNA sequencing to characterize bone metastases from eight cancer types. The findings identify three distinct immune ecosystem archetypes.

2.476. Cell therapy for patients with amyotrophic lateral sclerosis shows promise in human trials

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Dr. Simrit Parmar, an associate professor in the College of Medicine at Texas A&M University and founder of the clinical-stage biotech company Cellenkos Inc. in Houston, has invented a new cell therapy that shows strong promise for the treatment of amyotrophic lateral sclerosis (ALS), aplastic anemia and other devastating diseases.

2.477. Enzalutamide helps extend life for men with advanced prostate cancer, five-year follow-up finds

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The combination of enzalutamide with androgen deprivation therapy (ADT) significantly increases the chance of five-year survival for men with metastatic hormone-sensitive prostate cancer, according to a five-year follow-up of the global ARCHES study led by the Duke Cancer Institute.

2.478. Weight loss linked to nerve cells in the brain

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Semaglutide belongs to a group of drugs called GLP-1R agonists and has been shown to effectively reduce food intake and body weight. The drug is already well established as part of the treatment for obesity and type 2 diabetes, but can cause side effects such as nausea and muscle loss.

2.479. Statement For Regional Director, WHO Eastern Mediterranean Region on Occupied Palestinian territory

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WHA78, Geneva, 19-27 May 2025Agenda item: 20Document: A78/16 Chair, Your Excellencies, Director-General As outlined in the Director-General’s report, health conditions in the occupied Palestinian te

2.480. Vascularized stem cell islet organoids offer improved model for diabetes research

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Researchers led by Maike Sander, scientific director of the Max Delbrück Center, have developed a vascularized organoid model of hormone-secreting cells in the pancreas. The advance, published in Developmental Cell, promises to improve diabetes research and cell-based therapies.

2.481. Statement For Regional Director, WHO Eastern Mediterranean Region on Emergencies

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WHA78, Geneva, 19-27 May 2025Agenda item: 17.1Document: A78/13 Chair, Your Excellencies, Director-General, The WHO Eastern Mediterranean Region shoulders one-third of the world’s humanitarian burden

2.482. Novel immune cell population may offer alternative target for tuberculosis vaccines

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There is no highly effective vaccine against tuberculosis (TB), which remains an infection of global concern. Charles Kyriakos Vorkas, MD, an infectious diseases physician-scientist at the Renaissance School of Medicine (RSOM) at Stony Brook University, and colleagues identified a novel population of immune cells that could serve as an alternative target for TB vaccines and immune-directed therapy. Their findings are detailed in a paper published in Scientific Reports.

2.483. Statement For Regional Director, WHO Eastern Mediterranean Region on Poliomyelitis

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WHA78, Geneva, 19-27 May 2025Agenda item: 17.5Document: A78/4 Chair, Your Excellencies, Director-General, When we committed to eradicate polio in 1988, the world was different. Today, conflict, climat

2.484. More can be done to prevent common type of stroke, say experts

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Subarachnoid hemorrhage, the third most common type of stroke, accounting for 5–10% of all cases, could be drastically reduced worldwide through health and lifestyle changes, according to NZ, Australian and international researchers.

2.485. Mitochondrial DNA mutation accumulation may not be a determining factor in aging

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The human genome is broadly classified into the genome residing in the cell nucleus (nuclear DNA) and the genome residing in the mitochondria (mitochondrial DNA: mtDNA). Mitochondria are cell organelles that produce energy essential for life activities through oxidative phosphorylation (mitochondrial respiration), and mtDNA encodes a set of genes required for mitochondrial respiration.

2.486. Potent new opioid carries high risk of overdose

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A potent opioid detected in Canberra for the first time in September 2024 carries a high risk of overdose, warn chemists from the Australian National University (ANU) and drug checking service CanTEST.

2.487. Muscle quality may hold clues to early cognitive decline

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Over the past decade, much research has focused on the connection between skeletal muscle health and cognitive disorders. Scientists have found that sarcopenia, a geriatric syndrome characterized by progressive loss of skeletal muscle mass and function, appears to be strongly associated with an elevated risk of dementia. The complex relationship between our muscles and brain health represents a promising frontier in preventive medicine, particularly as global populations continue to age.

2.488. Blood test offers faster, less invasive diagnosis for rare genetic diseases in children and infants

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Researchers from the University of Melbourne and Murdoch Children's Research Institute (MCRI) have developed a blood test capable of rapidly diagnosing rare genetic diseases in babies and children, eliminating the need for costly and invasive procedures and giving families earlier access to treatment.

2.489. Reactivation of specific memories can indirectly strengthen related ones, study finds

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Most humans can recall specific events and past experiences for long periods of time. This capability, referred to as episodic memory, is known to be in great part supported by the activity of neurons in the hippocampus and medial temporal lobe.

2.490. Children among four dead in Mexican measles outbreak

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A measles outbreak in Mexico has left four people dead this year, including three unvaccinated children, authorities said.

2.491. Trump admin sows doubt over vaccines in 'Make America Healthy Again' report

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A highly anticipated White House report outlining Health Secretary Robert F. Kennedy Jr.'s agenda devotes significant space to raising alarm over vaccines, while touching on environmental and nutrition concerns that remain at odds with broader administration actions.

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