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Precision reprogramming: How AI tricks cancer's toughest cells

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  • 2025-10-20 22:00 event
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Precision reprogramming: How AI tricks cancer's toughest cells
Scientists at University of California San Diego have developed a new approach to destroying cancer stem cells—hard-to-find cells that help cancers spread, come back after treatment and resist therapy. The new approach, which the researchers tested in colon cancer, leveraged artificial intelligence (AI) to identify treatments that can reprogram cancer stem cells, ultimately triggering them to self-destruct.

40. How new foreign worker visa fees might worsen doctor shortages in rural America

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There are almost 1.1 million licensed physicians in the United States. That may sound like a lot, but the country has struggled for decades to train enough physicians to meet its needs—and, in particular, to provide care in rural and underserved communities.

41. California to launch insulin for just $11 a pen

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California will start selling low-cost insulin on Jan. 1, nearly three years after Gov. Gavin Newsom announced a plan to make lifesaving medications more affordable for folks with diabetes.

42. Protein powders and shakes contain high amounts of lead, new report says—a pharmacologist explains the data

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Powder and ready-to-drink protein sales have exploded, reaching more than US$32 billion globally from 2024 to 2025. Increasingly, consumers are using these protein sources daily.

43. Why is migraine more common in women than men?

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We've known for a long time that women are more likely than men to have migraine attacks.

44. AI system delivers comprehensive cancer diagnosis

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The Hong Kong University of Science and Technology (HKUST) today launched SmartPath, a comprehensive artificial intelligence (AI) system designed to transform the entire pathology workflow for cancer care.

45. Minimally invasive surgery may improve outcomes in severe stroke

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Minimally invasive endoscopic surgery may be an effective and safe treatment for patients with intracerebral hemorrhage, the most severe type of stroke, according to results from a recent clinical trial published in JAMA Neurology.

46. Resistance to epilepsy treatments may wane over time, study suggests

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About one-third of patients with focal epilepsy, a common form of the neurological disorder, are believed to respond poorly to available therapies. Yet they too may eventually see improvement, if not total relief, from their seizures, a new study shows.

47. Like radar, a brain wave sweeps a cortical region to read out information held in working memory

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Imagine you are a security guard in one of those casino heist movies where your ability to recognize an emerging crime will depend on whether you notice a subtle change on one of the many security monitors arrayed on your desk. That's a challenge of visual working memory.

48. Ultra-endurance athletes test the metabolic limits of the human body

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When ultra-runners lace up for races that stretch hundreds of miles and days, they're not merely testing their mental grit and muscle strength—they're probing the limits of human biology. Reporting in Current Biology, researchers found that even the most extreme athletes cannot surpass an average "metabolic ceiling" of 2.5 times their basal metabolic rate (BMR) in energy expenditure.

49. Precision reprogramming: How AI tricks cancer's toughest cells

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Scientists at University of California San Diego have developed a new approach to destroying cancer stem cells—hard-to-find cells that help cancers spread, come back after treatment and resist therapy. The new approach, which the researchers tested in colon cancer, leveraged artificial intelligence (AI) to identify treatments that can reprogram cancer stem cells, ultimately triggering them to self-destruct.

50. NHS policies to improve care for people taking multiple medicines may not be effective

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Current NHS policies designed to improve care for people taking multiple medicines may not be effective, according to new research.

51. Previously unknown mechanism in pre-eclampsia discovered

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Pre-eclampsia is one of the most serious complications in pregnancy, affecting millions of women and newborns worldwide. Despite intensive research, it has remained unclear what processes in the placenta lead to the disease. Now, a research team led by the Medical University of Vienna has discovered a previously unknown mechanism that plays a decisive role in the development of pre-eclampsia. The results, published in the journal Nature Communications, could open up new possibilities for diagnosis and treatment.

52. Teclistamab T-cell therapy shows promise in patients with drug-resistant autoimmune disease

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Research led by Friedrich-Alexander-Universität Erlangen–Nürnberg provides evidence that teclistamab may offer therapeutic benefit for patients with severe forms of treatment-resistant autoimmune diseases.

53. Oral drug demonstrates promising anti-tumor activity in patients with advanced lung cancer

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The oral targeted therapy sevabertinib led to tumor reduction and manageable side effects in patients with HER2-mutant non-small cell lung cancer (NSCLC), according to data from a trial led by researchers at The University of Texas MD Anderson Cancer Center.

54. Immune-altering drug suppresses tumor-protecting cells and enhances stomach cancer treatment

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Working with an international team of collaborators, scientists at Columbia University have found a way to shift the balance of a type of white blood cell inside a stomach tumor, causing the immune system to recognize and attack the cancer instead of ignoring it. The work, published in the August issue of Cancer Cell, also sheds light on immune functions that may drive many other diseases.

55. Bribing kids to eat vegetables might backfire—here's what to do instead

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It's a tactic many parents know well: "Eat two bites of broccoli, and then you can have dessert."

56. Nature images on Instagram can boost well-being and positive emotions, researchers say

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Scientists have found that viewing nature images on Instagram can have a positive impact on users' well-being and emotions, in contrast to prevailing narratives about social media use.

57. Deadly diarrhea germ targets white patients, study says

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An opportunistic bacterial infection that causes deadly diarrhea is more likely to kill white patients than Black or Hispanic people, a new study presented at IDWeek says.

58. Transformative eye research expands donor pool for corneal transplant patients

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Many eye banks won't accept corneas from donors with diabetes, concerned they might be harder to prepare for transplant surgery or are more likely to fail.

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