Psoriasis-linked gene mutation also impacts gut health, scientists discover

Researchers from the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine), have published a review on BH3 mimetics—a new class of drugs that are reshaping the treatment landscape for acute myeloid leukemia (AML), one of the most aggressive and treatment-resistant blood cancers. The work is published in Nature Reviews Clinical Oncology.

Pain affects activity levels, but how individuals understand and act in the face of pain can make a difference, a new study from the University of Portsmouth has found.

Abdominal and chest pain. Injuries. Breathing difficulty. Infections. Mental health emergencies. Those are some of the most common reasons why people go to the local emergency department.

As emergency medicine has emerged as a distinct medical discipline, there has been a shift in responsibility for a key task in emergency departments: managing emergency airways to help patients get enough oxygen. But how widespread is that shift?

Grape seed extract—a dietary supplement made from the seeds of wine grapes—has been investigated to see if it can help reduce blood cholesterol levels and high blood pressure. But can it also help slow down the growth of prostate cancer in men who have already undergone treatment?

An endoscopy—using a fiber‐optic tube to peer inside the body and collect biopsy samples—can be an invaluable way to detect cancer of the esophagus. But sometimes, an endoscopy can miss esophageal cancer, which doesn't get detected until weeks or months later.

Up to 60% of congenital and early-onset hearing loss is caused by genetic mutations in an inherited gene, and gene therapy has recently emerged as a potential treatment option. To provide a standardized framework for conducting safe, high-quality clinical trials, a group of international experts has put together guidelines on the administration of gene therapy for hereditary hearing loss.

Scientists have known hormone-sensitive lipase (HSL) as the enzyme that releases energy stored in our fat. Yet patients born without this protein do not become obese: on the contrary, they lose their adipose tissue, developing lipodystrophy with severe metabolic complications.

The United States continues to face a growing maternal health crisis. Despite being one of the most resource-rich nations in the world, America has the highest maternal mortality rate among wealthy countries and it's worsening. A 2025 report found that nearly half of U.S. counties lack a single obstetrician, midwife or birthing facility, creating what experts call "maternity care deserts."

Socializing could help to reverse frailty in older people, according to new research published in the American Journal of Epidemiology.

A new study from the University of Eastern Finland shows that images portraying dementia in Finnish newspapers often paint a clichéd and negative picture. The findings were published in the journal Age and Ageing.

Companies running private Medicare and Medicaid insurance plans inaccurately list many mental health professionals as being available to treat the plans' members, a new federal watchdog report says.

For decades, scientists have thought they understood the biochemical machinery that causes asthma—inflammation in the lungs that constricts airways and makes it hard to breathe.

Through the 1990s and early 2000s, guidelines for treating a concussion called for complete mental and physical rest. Current guidelines recommend a gradual resumption of cognitive and physical activity while consistently remaining engaged in typical daily activities as much as possible, but many clinicians are still following outdated guidelines and are advising patients to avoid sensory stimulation and activity following a concussion.

If you have ever watched a frightening movie which seemed so real, you felt a physical sensation in your own body if the characters on screen were hurt, you could be experiencing a phenomenon known as vicarious pain.

Liver disease is usually caused by one of three factors: alcohol consumption, fat buildup in the liver linked to obesity, diabetes and high cholesterol, or hepatitis B and C.

A new study from Saint Louis University (SLU) reveals that individuals with frequent heartburn—clinically known as gastroesophageal reflux disease (GERD)—have a higher chance of being diagnosed with alcohol use disorder (AUD) within two years. Researchers are urging primary care providers to screen GERD patients for alcohol misuse during routine visits.

While news feeds and social media are abuzz with unproven claims about links between acetaminophen and autism in children, there are well-established concerns about the harmful effects of an overdose of the over-the-counter pain and fever medication.