Radiation therapy overcomes immunotherapy resistance in some cancers

Researchers from the University of Turku and Turku University Hospital, Finland, led by Docent Sami Ventelä and Professor Jukka Westermarck, have developed a diagnostic tool that can revolutionize the treatment guidance of head and neck squamous cell carcinoma.

Nurses play a critical role in recognizing and responding to end-of-life needs in aged care, often identifying signs of decline up to a year before death.

Researchers from the RIKEN Center for Integrative Medical Sciences in Japan and collaborators have used genetic analysis and experiments to discover that the subjective responses of Japanese people to alcohol can be divided into three clear clusters. This research, published in Neuropsychopharmacology, could help identify people at risk for alcohol-related disorders.

Common sexually transmitted infections (STIs) during pregnancy have been linked to a higher risk of significant birth complications including preterm birth, stillbirth and babies born smaller than expected, according to a new, large-scale Curtin University study.

A new study by NYU Langone Health researchers found that the shutdown of a significant fossil fuel pollution source near Pittsburgh, PA, resulted in immediate improvements in respiratory health. The study is available online in the American Journal of Respiratory and Critical Care Medicine.

King County had two goals when it purchased more than a dozen hotels to convert into housing for people living on the streets—end homelessness for a bunch of people and improve their health.

In the wake of January's deadly wildfires, Los Angeles County leaders are weighing a disaster registry intended to help disabled and senior residents get connected to emergency responders to bring them to safety during disasters.

A four-day work week can lead to happier and more productive, dedicated employees, a new global study found.

An international team of researchers has made a key discovery: many children and young adults in Sub-Saharan Africa diagnosed with type 1 diabetes (T1D) may have a different form of the disease—one not caused by the immune system, unlike classic T1D. This discovery could change how diabetes is diagnosed, treated and managed across the region, paving the way for more accurate care and better outcomes.

Urgent care visits are often associated with inappropriate prescriptions of antibiotics, glucocorticoids, and opioids, according to a research letter published online in the Annals of Internal Medicine.

Not all probiotics are created equal, according to new research from North Carolina State University.

Millions of people worldwide suffer from hydrocephalus, or a buildup of excess cerebrospinal fluid in the brain, and which recently received greater attention when Billy Joel announced his diagnosis. Treatment usually involves surgical placement of shunts to divert fluid away, but this procedure often leads to complications, infections, and multiple re-treatments.

For older adults with diabetes, there is no clear evidence to suggest that the incidence of dementia differs for those using glucagon-like peptide 1 receptor agonists (GLP-1 RAs) versus dipeptidyl peptidase-4 inhibitors (DPP4is), according to a study published online in the Annals of Internal Medicine.

The U.S. Food and Drug Administration has approved GSK's prefilled syringe presentation of Shingrix (zoster vaccine recombinant, adjuvanted) for the prevention of shingles (herpes zoster).

Around 10 million people globally live with the life-threatening virus HTLV-1. Yet it remains a poorly understood disease that currently has no preventative treatments and no cure.

Cellular senescence is a process in which the cell cycle becomes permanently arrested, thereby inhibiting cell division, proliferation and growth. Various cellular stresses, such as DNA damage, telomere shortening and oxidative stress, can trigger cellular senescence. Physiologically, cellular senescence contributes to tissue development, repair and critical biological processes such as embryogenesis, whereas, pathologically, it plays a key role in diverse conditions, including age-related disease, some cancers, Alzheimer's disease, and others.

A study by investigators at the Icahn School of Medicine at Mount Sinai, in collaboration with colleagues from Rabin Medical Center in Israel and other collaborators, suggests that even the most advanced artificial intelligence (AI) models can make surprisingly simple mistakes when faced with complex medical ethics scenarios.

An antibody treatment developed at Stanford Medicine successfully prepared patients for stem cell transplants without toxic busulfan chemotherapy or radiation, a Phase I clinical trial has shown.