Rapamycin linked to DNA damage resilience in aging human immune cells

Peking University scientists have developed a cancer therapy that could make life-saving treatment accessible to any patient, anywhere. A team led by Professor Wei Wensheng from Peking University, collaborating with the PLA General Hospital and biotech company EdiGene Inc., has developed a novel cancer therapy that could make advanced treatment accessible to many more patients. Their study is published in the journal Cell.

As Florida plans to phase out childhood vaccine mandates, Northeastern policy experts say it would undo decades of public health protections and expose children to once-common pediatric diseases that devastated communities.

Clinical data demonstrate the combination of tarlatamab with anti-PD-L1 therapy as first-line maintenance has an acceptable safety profile and resulted in unprecedented overall survival in patients with extensive-stage small cell lung cancer (ES-SCLC).

Some of the populations with the highest risk for Alzheimer's disease remain greatly underrepresented in clinical trials—and a new study helps explain why.

40 million people live with HIV globally, and that number continues to rise. While therapies exist to reduce the amount of HIV in a patient's body and, in turn, reduce HIV symptoms, there remains no cure. Engineering better drugs and eventually a cure depends on our ability to answer foundational questions like: How does HIV invade and replicate in host cells?

In the U.K. there are more than 40,000 out-of-hospital cardiac arrests (OHCA) annually, but fewer than 10% of people survive. Early CPR (cardiopulmonary resuscitation) and use of an Automated External Defibrillator (AED) to restart the heart can at least double the chance of survival. AEDs are safe for the public to use, even without training, but it can be difficult for bystanders to locate and retrieve one quickly during an emergency.

Whether training for a marathon, fitting in a quick gym session after work, or running onto the footy field for a professional match, it seems that the warm-up might be just as important as the exercise itself.

Giving birth is hard enough; postpartum depression can make adjusting to parenthood all the more difficult. A healthy diet is essential for new mothers to build strength after such a taxing ordeal, but what if what they eat could also lower the risk of baby blues?

Researchers from the University of Adelaide have taken existing questionnaires used to measure chronic pain and made them accessible for children and young people with cerebral palsy.

An international team of scientists has revealed how rogue rings of DNA that float outside of our chromosomes—known as extrachromosomal DNA, or ecDNA—can drive the growth of a large proportion of glioblastomas, the most common and aggressive adult brain cancer. The discovery could open the door to much-needed new approaches to diagnose glioblastoma early, track its progress and treat it more effectively.

Researchers at the University of Alberta have found a way to measure how engaged people living with dementia are when they're playing a computer game—which could pave the way to new treatments that use gaming to stave off the onset or progression of cognitive decline.

Researchers have uncovered new evidence that challenges long-standing beliefs about asymptomatic malaria infections. The study, led by Monash University's Professor Diana Hansen and published in Molecular Systems Biology, focused on Plasmodium vivax, the most widespread malaria parasite and a major obstacle to global elimination efforts.

An international group of researchers has developed a new tool that can help identify problematic randomized controlled trials (RCTs), including fraudulent studies, where there are serious concerns about trustworthiness.

It was March 2020, and Robert Gordon was about to kick some 80,000 people off health insurance.

Physicians rely on nuclear medicine scans, like SPECT scans, to watch the heart pump, track blood flow and detect diseases hidden deep inside the body. But today's scanners depend on expensive detectors that are difficult to make.

Creatine is shedding its gym-bro reputation, unlocking lucrative new markets as women and older Americans get wise to the benefits of the long-stigmatized supplement. Sales are booming as a result.

Seniors in some parts of the country say they are being denied COVID-19 vaccinations amid an ongoing spike in cases, leading to rising frustration over new Trump administration policies that are making it harder to get the shots.

A cup of coffee or tea in the morning or an afternoon caffeine pick-me-up is usually fine for most adults. But parents might want to take a closer look at caffeine and other ingredients in the drinks their kids love.