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Researchers engineer rare immune cells to create powerful new cancer vaccine

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  • 2025-07-21 22:37 event
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Researchers engineer rare immune cells to create powerful new cancer vaccine
In a new study published in Cancer Immunology Research, scientists at the Icahn School of Medicine at Mount Sinai have developed a novel method to generate billions of rare immune cells known as conventional type I dendritic cells (cDC1s), potentially paving the way for a new class of off-the-shelf cellular cancer vaccines.

1.539. Sun advice from a skin cancer researcher and physician

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There is certainly growing awareness of the damaging effects of overexposure to the sun, including skin cancers.

1.540. Tool helps scientists spot source of neurological disease with statistics and data science

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Carnegie Mellon University researchers have developed a statistical tool that could help pinpoint the genetic changes that cause diseases like Alzheimer's and schizophrenia. While scientists have long identified genes associated with these conditions, confirming which changes actually cause disease has remained a challenge. The tool, causarray, offers hope.

1.541. Listening well can move you, literally, study finds

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Within every human culture rests the potential for a distinctly positive emotional experience that's variously characterized, in English, as feeling moved, emotionally touched, or heartwarming. Other languages rely on similar contact metaphors to describe this feeling, which has been labeled only recently by researchers as Kama Muta, a Sanskrit word for being "moved by love."

1.542. Why it can be harder to sleep during the summer

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As the days stretch long and the sun lingers late into the evening, most of us welcome summer with open arms. Yet for a surprising number of people, this season brings an unwelcome guest: insomnia.

1.543. FDA elevates Dubai chocolate spread recall to Class 1 over salmonella risk

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The U.S. Food and Drug Administration (FDA) has escalated the recall of a popular Dubai chocolate spread sold nationwide to its highest alert level due to salmonella risks.

1.544. New survey data reveals nearly one-third of Americans engage in a 'sleep divorce'

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It's no secret that good sleep makes for better days and stronger relationships, but how couples get that rest, in the same bed or separately, has Americans talking. According to new survey data from the American Academy of Sleep Medicine, nearly one-third (31%) of U.S. adults have opted for what has been coined a "sleep divorce," or sleeping in another bed in the same bedroom or in another space in the home to accommodate a bed partner. Adults aged 35 to 44 are most likely to engage in sleep divorce (39%) and 65 or older the least likely (18%) to do so.

1.545. About a third of pregnant women in the US lack sufficient vitamin D to support healthy pregnancies

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Children whose mothers had higher vitamin D levels during pregnancy scored better on tests of memory, attention and problem-solving skills at ages 7 to 12 compared with those whose mothers had lower levels. That is a key finding of a new peer-reviewed study that my colleagues and I published in the American Journal of Clinical Nutrition.

1.546. Why visual training, including juggling, can be a secret weapon in elite sports

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Much of the pre-series attention on the 2025 British and Irish Lions tour of Australia has been on injuries, player omissions and personal rivalries.

1.547. Study reveals how immune cells transform to aid tissue healing after injury

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Regulatory T cells (Treg cells) are a specialized subgroup of immune cells that play a central role in the human immune system. These cells can suppress erroneous and therefore harmful immune reactions that can lead to autoimmune diseases, for example. Furthermore, they actively promote the regeneration of tissue after injuries and thus orchestrate the wound healing process.

1.548. Researchers engineer rare immune cells to create powerful new cancer vaccine

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In a new study published in Cancer Immunology Research, scientists at the Icahn School of Medicine at Mount Sinai have developed a novel method to generate billions of rare immune cells known as conventional type I dendritic cells (cDC1s), potentially paving the way for a new class of off-the-shelf cellular cancer vaccines.

1.549. What's the difference between sperm and semen? And can pre-ejaculate get you pregnant?

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Semen, sperm, spunk, cum, ejaculate, pre-cum, seminal fluid. These are just some of the many words we use to describe what comes out of an erect penis.

1.550. Autistic teens who mask in social settings display distinct brain activity patterns

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Some autistic teens often adopt behaviors to mask their diagnosis in social settings helping them be perceived—or "pass"—as non-autistic. For the first time, researchers are able to observe brain functions that differ in those who "pass as non-autistic," which could lead to a better understanding of the cognitive toll of this kind of masking, and of how these individuals could be more effectively supported.

1.551. Genome editing has corrected rare brain mutations in mice; could also help fight neurological diseases

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Scientists have corrected gene mutations in mice causing an ultra-rare disease by editing DNA directly in the brain with a single injection, a feat with profound implications for patients with neurological diseases.

1.552. Scientists identify cancer drugs that may reverse the changes that occur in the brain during Alzheimer's

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Scientists at UC San Francisco and Gladstone Institutes have identified cancer drugs that promise to reverse the changes that occur in the brain during Alzheimer's, potentially slowing or even reversing its symptoms.

1.553. Exploring the adverse effects of antipsychotic medications on oral health

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A research group in the Department of Pharmacology of the University of the Basque Country has investigated the adverse reactions that antipsychotics can cause in the mouth. The study was based on data from the European pharmacovigilance database EudraVigilance and revealed that the most common problems are related to salivary flow disorders (such as excessive salivation and dry mouth), oral inflammation and tooth loss. The research is published in the journal Oral Diseases.

1.554. Relationship-building key to addressing oncologist shortages in rural care

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Rural oncologists reported the loss of expertise and professional support as key impacts of the departure of "linchpin colleagues," according to a new Dartmouth-led study published in the journal JCO Oncology Practice. The study, which shares insights about the effects of specialist scarcity in rural settings, is helping researchers understand what strategies may work best in addressing gaps in care.

1.555. Low vitamin D may increase your risk of being hospitalized with COVID-19

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As the latest wave of COVID-19 shows no signs of abating, University of South Australia experts say it's not just booster shots that could offer protection—healthy levels of vitamin D may also play a role.

1.556. Largest database of brain tumor gene expression created to speed discovery of new treatments

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A new online tool developed by researchers at the University of Louisville promises to speed up the discovery of treatments for brain and nerve tumors, especially rare ones that have had limited research attention.

1.557. Why some people persist in harmful behaviors—even when they know where they're going wrong

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Why do some people keep making choices that hurt them, even when the outcomes are obvious?

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