Researchers redesign vaginal speculum to ease fear and pain

An international team of researchers led by Professor Morris Brown FRS at Queen Mary University of London found that Baxdrostat, a drug belonging to a new class of aldosterone synthase inhibitors, led to an average fall in blood pressure of 25 mmHg. This is two to three times the reduction typically achieved by a single antihypertensive drug.

Food taxes and subsidies that make healthy foods cheaper and ultra-processed foods more expensive could significantly improve Australian diets and help reduce chronic disease, according to a new study by The George Institute for Global Health, published in Nature Food.

Short-form video isn't new. Before TikTok, there was Vine—a platform that popularized 6-second video clips and helped redefine what it meant to go viral. The "Only a spoonful" of ice cream skit lives rent-free in many netizens' heads. But Vine arrived before mobile internet and algorithmic feeds fully matured. Though the site did not stand the test of time, newer platforms built on its legacy and further refined this engaging media format.

Researchers at Karolinska Institutet have identified over 250 proteins that are strongly affected by malaria, which could help predict the severity of the disease and thus enable faster treatment for the most critical patients.

A groundbreaking international study of 161,981 participants across 40 countries published in Nature Medicine reveals that air pollution, social inequality, and weak democratic institutions substantially accelerate aging. The collaborative study involves leading researchers from the Global Brain Health Institute in Trinity College Dublin.

A bottleneck in ensuring access to widespread molecular diagnostics, especially in low- and middle-income countries, has been the high cost and logistical complexities associated with rapid, point-of-care tests.

Researchers from Helmholtz Munich and the Technical University of Munich have developed a novel method to track cancer treatment responses in individual cells—without the need for dyes or labels.

A research team led by Professor Takuya Yamamoto (Department of Life Science Frontiers) and Professor Yasuhiro Yamada at the University of Tokyo has developed a novel in vivo system that reveals how senescent cells behave in living tissues and influence aging through complex, heterogeneous mechanisms. The research is published in the journal Nature Aging.

New research has revealed a substantial increase in GHB-related ambulance attendances across Australia, with Victoria recording the highest rate and Greater Geelong emerging as a regional hotspot.

A research team at the Medical University of Vienna has developed a blood test that allows the identification of individuals at risk for developing multiple sclerosis (MS) with a high degree of certainty years before the onset of symptoms. As a result, in the future, diagnostic and therapeutic measures could be taken early enough to delay or even prevent the onset of the disease. The research has just been published in Nature Communications.

Artificial intelligence (AI) is revolutionizing health care, enhancing diagnostics, streamlining treatment, and improving patient outcomes. However, a recent study published in Digital Health reveals that these advancements remain largely concentrated in the Global North, leaving the Global South at a significant disadvantage.

A Finnish population study shows that signs related to Alzheimer's disease may already be found in the brain in middle age. In the future, blood-based biomarkers associated with Alzheimer's disease could allow earlier detection of the disease. This would allow preventive treatment to be targeted at the right individuals while the disease is still at the mild stage.

Nicole Silva's 4-year-old daughter was headed to a relative's house near the southern Colorado town of La Jara when a vehicle T-boned the car she was riding in. A cascade of ambulance rides ensued—a ground ambulance to a local hospital, an air ambulance to Denver, and another ground ambulance to Children's Hospital Colorado.

A study conducted by researchers at Saint Louis University found that patients with depression were more likely to have uncontrolled diabetes over time and that depression contributes to a heightened economic burden to diabetes management.

Kaiser Permanente Washington scientists report that higher cumulative anticholinergic exposure predicted a faster decline in gait speed and grip strength among older adults.

In order to produce effective targeted therapies for cancer, scientists need to isolate the genetic and phenotypic characteristics of cancer cells, both within and across different tumors, because those differences impact how tumors respond to treatment.

Socially isolated older adults are at increased risk of developing diabetes and high blood sugar, according to a study being presented at ENDO 2025, the Endocrine Society's annual meeting in San Francisco, Calif.

Mothers experiencing depression have considerable challenges across multiple parenting domains, according to a global systematic review published in the Harvard Review of Psychiatry.