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Review compares efficacy, safety of treatments for hidradenitis suppurativa

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  • 2025-07-08 06:10 event
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Review compares efficacy, safety of treatments for hidradenitis suppurativa
The efficacy and safety of currently approved and pipeline medications for moderate-to-severe hidradenitis suppurativa (HS) are compared in a systematic literature review and network meta-analysis published online July 2 in JAMA Dermatology.

745. A single disorder upended Pennsylvania's medical marijuana program

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A single mood disorder might have driven a rapid increase in Pennsylvania's medical marijuana program, a new study says.

746. Why are women twice as likely to develop Alzheimer's as men?

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A neglected piece of the Alzheimer's puzzle has been getting increased scientific attention: why women are twice as likely as men to develop the disease.

747. A bigger waist may increase the risk of dying for older women

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Older women with larger waist circumference may be at a much greater risk of dying for any given BMI, according to international research, which monitored women over more than two decades. The study found that for post-menopausal women aged 50–79, taking waist circumference into account along with BMI, better reflected the role obesity plays in the risk of dying than using BMI alone.

748. Roundworm study identifies proteins that could mediate neuron-glia communication as brain ages

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The human brain is comprised of two main types of cells, known as neurons and glia. The first are responsible for transmitting electrical and chemical signals, while the latter support and protect neurons.

749. Scientists create biological 'artificial intelligence' system

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Australian scientists have successfully developed a research system that uses 'biological artificial intelligence' to design and evolve molecules with new or improved functions directly in mammal cells. The researchers said this system provides a powerful new tool that will help scientists develop more specific and effective research tools or gene therapies.

750. Liquid biopsy test uses RNA modifications to detect early-stage colorectal cancer with 95% accuracy

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Liquid biopsies are tests that detect signs of cancer through a simple blood draw. Unlike traditional biopsies, which require removing a piece of tissue, a liquid biopsy typically looks for mutations or modification changes in fragments of DNA from cancer cells circulating in the blood.

751. Hospital-based obstetric care declines across US, hitting rural states hardest

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Access to obstetric care is a critical determinant of maternal and infant health. However, a new study led by the University of Minnesota School of Public Health found that hospital-based obstetric care has declined in recent years, with variability across states.

752. What's behind the enormous increase in early-onset gastrointestinal cancers?

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A paper in the British Journal of Surgery indicates that early-onset gastrointestinal cancer rates are rising dramatically across the globe.

753. Matching your workouts to your personality could make exercising more enjoyable and give you better results

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Finding motivation to exercise can be the greatest challenge in working out. This might be part of the reason why less than a quarter of people achieve the activity goals recommended by the World Health Organization.

754. Review compares efficacy, safety of treatments for hidradenitis suppurativa

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The efficacy and safety of currently approved and pipeline medications for moderate-to-severe hidradenitis suppurativa (HS) are compared in a systematic literature review and network meta-analysis published online July 2 in JAMA Dermatology.

755. Breast cancer: Treatment decisions on basis of biomarker-based test can be harmful

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The German Institute for Quality and Efficiency in Health Care (IQWiG) has examined the pros and cons of biomarker-based tests to inform decisions about adjuvant chemotherapy for patients with a certain type of breast cancer, i.e., first-time, hormone receptor-positive and HER2/neu-negative breast cancer.

756. The myth of 200 daily food decisions: Study challenges widely-cited claim

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Researchers at the Max Planck Institute for Human Development have critically examined the basis for a frequently cited figure: that people make more than 200 unconscious decisions about food every day. This figure has circulated in scientific publications, the media, and health promotion campaigns for nearly 20 years without ever being empirically validated. An article published in the journal Appetite shows why a more nuanced view of eating behavior is needed.

757. New blood biomarker predicts progression of Alzheimer's disease even in its earliest stages

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A team of researchers at the Sant Pau Research Institute (IR Sant Pau) has demonstrated that the plasma biomarker p-tau217, obtained through a simple blood test, can predict the clinical progression of Alzheimer's disease even in its earliest stages, when symptoms are not yet evident. The study, published in the journal Neurology, reinforces the role of blood tests in the future of diagnosing and monitoring dementias.

758. Biobank data helps explain why some individuals experience more side effects from antidepressants

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Researchers at the University of Tartu Institute of Genomics have gained a deeper understanding of why some people are more prone to experiencing side effects when taking antidepressants.

759. Medical cannabis program changes drastically when adding anxiety as a qualifying condition, study finds

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Within months of Pennsylvania's medical cannabis program adding anxiety as a qualifying condition, that diagnosis quickly rose to become the most common for cannabis certifications, according to a study by researchers at the University of Pittsburgh and Johns Hopkins University. The study was published in Annals of Internal Medicine.

760. 1 in 5 overweight adults could be reclassified as obese according to new framework

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A cross-sectional and longitudinal analysis examined the distribution of people by obesity level using the European Association for the Study of Obesity's (EASO) new framework and determined the risk of death of those newly diagnosed with obesity by this framework.

761. The years 2002 to 2022 saw an increase in teen handgun-carrying in Florida

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In Florida, adolescent handgun-carrying is increasing, while handgun-carrying in school, favorable attitudes toward handgun0carrying in school, and ease of handgun access are decreasing, according to a study published online July 7 in Pediatrics.

762. Study reveals accurate association between weak handgrip and a host of diseases among over-50s

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Researchers have provided robust scientific evidence that ailments like depression, high blood pressure, diabetes mellitus, Alzheimer's disease, osteoarthritis, and difficulties performing daily activities are associated with a frail handgrip, particularly among older adults.

763. The risk of postoperative proliferative vitreoretinopathy is lower with cannabis use

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Patients undergoing retinal detachment (RD) repair with concomitant cannabis use have a lower risk of subsequent proliferative vitreoretinopathy (PVR) and requiring subsequent complex RD repair, according to a study published online July 3 in JAMA Ophthalmology.

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