Risk factors for metachronous colorectal cancer in Lynch syndrome investigated

Your feet are microbial hotspots. The area between your toes is packed with sweat glands, and when we wrap our feet in socks and shoes, we trap that moisture in a warm, humid cocoon that's ideal for microbial growth. In fact, your feet may be home to a miniature rainforest of bacteria and fungi, with anywhere from 100 to 10 million microbial cells per square centimeter of skin surface.

Employees of the technology transfer center ANAXAM and researchers from the Paul Scherrer Institute PSI used the unique analytical methods available at PSI to look inside pre-filled syringes. They found that, in rare cases, zinc from the needle shield can leach into the drug solution to be injected and possibly contribute to syringe clogging.

Spinal cord damage—whether from traumatic injury or conditions such as spina bifida—can have a profound impact on bladder function. This can result in neurogenic bladder, a problem in which damage to the nerves involved in urination leads to a loss of bladder control. Neurogenic bladder is currently managed with medication, Botox injections, and catheterization.

No one knows exactly how many doses of coronavirus vaccines were discarded during the pandemic. But the numbers are high. The media reported that 125,000 doses went unused in Norway during 2021 alone.

Nitrous oxide deaths in the United States spiked by more than 500% between 2010 and 2023, a new study indicates.

Brazilian researchers have taken an important step toward precision medicine by identifying four genes that can predict which melanoma patients will not respond to immunotherapy. Although this treatment has revolutionized the fight against melanoma, the most aggressive and lethal form of skin cancer, it is still costly and variable in efficacy, which limits its use, especially in the SUS (Sistema Único de Saúde), the country's national public health system. The goal is to use this finding to create ways to identify patients who are eligible for treatment, thus reducing costs in the public health system.

When school starts in West Virginia next month, 240,000 students in districts large and small will notice something missing from their cafeteria trays.

Depression is a mental health disorder characterized by a recurrent or persistent sadness and a loss of interest in activities that were previously deemed pleasurable, sometimes accompanied by changes in sleep, appetite and perceived energy levels. One of the most debilitating types of depression is major depressive disorder (MDD), which entails a pervasive low mood for a prolonged time, which in turn adversely impacts people's ability to engage in daily activities.

In a new study led by Children's Hospital of Philadelphia (CHOP), researchers found that novel eye-tracking metrics can help properly identify concussion-related vision disorders, a common phenomenon among patients with persisting post-concussive symptoms that last more than 28 days after their initial injury. The findings, recently published in the Journal of Sport and Health Science, suggest that objective infrared eye tracking could help identify which patients would benefit the most from referrals to and treatment from concussion specialists.

A new technology that harnesses artificial intelligence (AI) to analyze mammograms and improve the accuracy of predicting a woman's personalized five-year risk of developing breast cancer has received Breakthrough Device designation from the Food and Drug Administration (FDA). Developed by researchers at Washington University School of Medicine in St. Louis, the software has been licensed to Prognosia Inc., a WashU startup company.

The phrase "summer long balls" might sound like locker-room slang, but it's increasingly being mentioned on social media and online forums as a seasonal curiosity. In hot weather, men's scrotums which contain their testicles can appear looser or more pendulous—hence the name.

In a study, patients with irritable bowel syndrome with diarrhea, or IBS-D, who went on a low FODMAP diet saw an improvement of colonic barrier dysfunction, commonly known as "leaky gut."

The microbial community in the human gut plays a central role in various diseases. An important form of chemical communication between the gut microbiome and the human body comes from small molecules produced when bacteria in the digestive system break down food. These include acids such as acetate, propionate, and butyrate. These fermentation products in the gut can regulate the immune system, promote the regeneration of the intestinal mucosa and influence human behavior. Although these effects are known, the daily dose of these molecules to which the human body is exposed was previously unknown.

HAEZI group researchers analyzed the impact on memory exerted by the declaration of a state of alarm due to COVID. From the accuracy and certainty that the respondents revealed in their memories, they concluded that the impact was significant and that to leave a lasting impression an event does not have to be unexpected. They also studied how age influences memories and found that memories become less detailed with the advancing years.

Researchers led by the University of Geneva and École Polytechnique Fédérale de Lausanne report that neural anticipation of virtual infection triggers an immune response through activation of innate lymphoid cells.

Firefighters work hard saving lives, and in the process put their own lives at heightened risk from skin, kidney and other types of cancers, a new American Cancer Society (ACS) study finds.

Health officials have confirmed Wisconsin's first human case of West Nile virus in 2025.

From fetal stages through adolescence, the brain undergoes rapid, layered development—from basic motor skills to complex emotional regulation. Yet this very dynamism, coupled with children's physical and behavioral traits, makes brain imaging extraordinarily difficult. Common conditions like autism spectrum disorder (ASD), Attention-Deficit/Hyperactivity Disorder (ADHD), and perinatal brain injury often leave subtle but critical imprints on early neural architecture.