Rodent study reveals different signaling codes for learned skills and clues about human movement disorders
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- 2025-08-11 21:35 event
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Treatment with interferon or with glatiramer acetate? This question arises for many patients who receive a diagnosis of multiple sclerosis (MS) for the first time. Until now, the choice between the two could practically be made at random: both preparations are considered established basic therapies, both have relatively low side effects and both are relatively well tolerated. And, as with all immunomodulatory therapies, both do not help all people equally well. However, thanks to a study led by the University of Münster, there is now a clear criterion for choosing the medication.
Cornell researchers have developed an implant system that can treat type 1 diabetes by supplying extra oxygen to densely packed insulin-secreting cells, without the need for immunosuppression. The system could also potentially provide long-term treatment for a range of chronic diseases.
If the brain no longer responds properly to insulin (insulin resistance), this can lead to weight gain, diabetes, and Alzheimer's disease. Researchers at the German Center for Diabetes Research (DZD) in Potsdam and Tübingen have discovered small chemical modifications to genetic material (epigenetic changes) in the blood that indicate how well the brain responds to insulin. These markers could help to detect insulin resistance in the brain by means of a simple blood test. The findings are published in Science Translational Medicine.
Building upon the success of the first in utero brain surgery for vein of Galen malformation (VOGM) reported in 2023, new data published in JAMA provides further evidence for the potential use of fetal embolization for this condition.
New research from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King's College London in partnership with the Mayo Clinic and UNEEG medical, has found that an electronic device placed under the scalp is an effective and feasible means of accurately tracking epilepsy.
The human brain ages less than thought and in layers—at least in the area of the cerebral cortex responsible for the sense of touch. Researchers at DZNE, the University of Magdeburg, and the Hertie Institute for Clinical Brain Research at the University of Tübingen came to this conclusion based on brain scans of young and older adults in addition to studies in mice.
Research by sports scientists reveals that high-performance athletes face unique mental health challenges despite the well-established benefits of physical activity for depression prevention and treatment.
Artificial intelligence (AI) can help emergency department (ED) teams better anticipate which patients will need hospital admission, hours earlier than is currently possible, according to a multi-hospital study by the Mount Sinai Health System.
Approximately 70% of incarcerated youth in the United States have a mental disorder. The challenges in this population are profound—about 30% report suicidal thoughts, 12% have attempted suicide and 25% experience solitary confinement, a condition strongly associated with increased suicide risk. Depression is also widespread, affecting 10% to 25% of youth with moderate to severe symptoms.
Among the many wonders of the brain is its ability to master learned movements—a dance step, piano sonata, or tying our shoes—acquired through trial-and-error practice. For decades, neuroscientists have known that these tasks require a cluster of brain areas known as the basal ganglia.
Researchers from Tokyo Metropolitan University have discovered a new pathway by which cells counteract the action of alovudine, an important antiviral and anticancer drug. The paper is published in the journal Nucleic Acids Research.
Large language models (LLMs), used by more than half of England's local authorities to support social workers, may be introducing gender bias into care decisions, according to new research from the London School of Economics and Political Science (LSE).
What infectious disease is deadliest worldwide? HIV? COVID-19? Malaria?
A research team led by Virginia Commonwealth University has gained new insights into the molecular mechanisms that cause cocaine use disorder, identifying a potential therapeutic strategy to inhibit the drug's addictive effect.
Many people are familiar with the saying that a woman is "eating for two" during pregnancy. Although this is an exaggeration, nutritional needs do certainly increase during pregnancy to support the growing baby.
The world's largest conditional cash transfer program, the Bolsa Família Program (BFP), is associated with a substantial reduction in AIDS cases and deaths, especially among brown and black women with lower income and limited education.
Prediabetes, when blood sugar is higher than normal but not high enough to be considered diabetes, is more life-threatening in people aged 20–54 than it is in older populations, according to a paper published Aug. 7 in JAMA Network Open.
11 August 2025, Manama, Bahrain – World Health Organization (WHO) Regional Director for the Eastern Mediterranean Dr Hanan Balkhy has completed her first official visit – from 4 to 6 August 2025 – to the Kingdom of Bahrain. The visit reaffirmed the longstanding strategic partnership between WHO and the Government of Bahrain, highlighted Bahrain’s progress in advancing national and regional health priorities and set out a clear roadmap for enhanced cooperation in the years ahead. Dr Balkhy met with national health leaders, including Chairman of the Supreme Council for Health Lieutenant General Dr Sheikh Mohamed bin Abdullah Al-Khalifa and Minister of Health Dr Jaleela bint Al-Sayed Jawad Hassan. They reviewed Bahrain’s health sector achievements and identified specific areas for future collaboration, with a focus on the 3 regional flagship initiatives. Dr Balkhy held discussions with Commander of the Royal Medical Services Brigadier General Dr Shaikh Fahad bin Khalifa bin Salman Al Khalifa on national initiatives to strengthen the health workforce, and with members of the national health working groups on multisectoral strategies to address communicable and noncommunicable diseases. Continuous strengthening of primary health care, investment in a skilled and future-ready health workforce and the integration of innovation and technology into all levels of service delivery are central to Bahrain’s National Health Plan (2016–2025). Dr Balkhy’s site visits illustrated these priorities in action. At the Shaikh Abdulla bin Khalid Al Khalifa Health Centre Dr Balkhy observed Bahrain’s integrated, people-centred health service, recognizing it as a regional model for strengthening primary Read more...
Fentanyl and other high-potency synthetic opioids (HPSOs) are the leading cause of opioid overdose deaths in the United States. These substances have changed the way that hospitals start medication to treat opioid use disorder (OUD), but no standards exist.